Results 111 to 120 of about 2,157,684 (307)
Gene Therapy With Regulatory T Cells: A Beneficial Alliance
Frontiers in Immunology, 2018 Gene therapy aims to replace a defective or a deficient protein at therapeutic or curative levels. Improved vector designs have enhanced safety, efficacy, and delivery, with potential for lasting treatment.
Moanaro Biswas +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
The adoption of ecological fiscal transfers: An empirical analysis
Land Use Policy, 2019 The ecological fiscal transfers (EFT) from states to municipalities were adopted by 16 of the 26 Brazilian states since 1990s to stimulate and compensate districts for achieving some environmental goals. This study aims to understand the adoption of this economic-policy instrument by Brazilian states and argues that the vertical relations between the ...
Felipe Luiz Lima de Paulo +1 more
openaire +1 more source
Investigation of heat transfer augmentation through use of internally finned and roughened tubes : final summary report [PDF]
, 1970 This report summarizes a three-year program concerned with obtaining basic design information for tubes having a random roughness on the inside wall (RID) and tubing having continuous internal fins (Forge Fin).
Brown, G. S. +4 more
core
Ex vivo expansion of human T cells for adoptive immunotherapy using the novel Xeno-free CTS Immune Cell Serum Replacement [PDF]
, 2015 The manufacture of clinical grade cellular products for adoptive immunotherapy requires ex vivo culture and expansion of human T cells. One of the key components in manufacturing of T cell therapies is human serum (HS) or fetal bovine serum (FBS), which ...
Schjetne, Karoline W. +7 more
core +1 more source
FEBS Open Bio, EarlyView.Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
, 1991 In vitro incubation ofListeria-immune spleen cells (LISC) with recombinant interleukin-2 (rIL-2) for at least 3 days increased their ability to transfer antilisteria resistance to recipient mice.
C. J. Czuprynski, M. Haak-frendschot
core
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Functional genomics for improving adoptive T-cell transfer therapies
Journal for ImmunoTherapy of CancerAdoptive cell therapy (ACT) has shown remarkable success in the treatment of some malignancies, particularly leukemia. However, there are multiple factors that limit the durability of ACT in solid tumors, including dose-limiting toxicities, the ...
Saad S Kenderian +10 more
doaj +1 more source
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source