Results 91 to 100 of about 2,157,684 (307)
Citation: 'adoptive transfer' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.12850 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests
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Adoptively transferred macrophages for cancer immunotherapy
Journal for ImmunoTherapy of CancerBackground Macrophages have been classically associated with their innate immune functions of responding to acute injury or pathogenic insult, but they have been largely overlooked as primary initiators of adaptive immune responses.
Kyung Soo Park +8 more
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Hemin Decreases Pro-Inflammatory Th17 Cells and Cytokines in an Adoptive Transfer Model of Colitis [PDF]
, 2017 The goal of this research was to reduce disease in an adoptive transfer model of colitis using an immunomodulatory therapy, hemin, while correlating this response to changes in cytokines and effector T-cell differentiation.
Graham, Sean M.
core
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Downregulation of L-arginine metabolism in dendritic cells induces tolerance to exogenous antigen
International Journal of Immunopathology and Pharmacology, 2017 Dendritic cells (DC) are potential tools for therapeutic applications and several strategies to generate tolerogenic DCs are under investigation. When activated by cytokines and microbial products, DCs express mediators that modulate immune responses. In
Patricia U Simioni +2 more
doaj +1 more source
Медицинская иммунология, 2014 Contact sensitivity is a classical T cell-mediated, clinically important phenomenon elicited by small molecular weight molecules (haptens) that bind to host proteins to form a complete antigen.
S. I. Pavlova +3 more
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Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Adoption handbook and directory of adoption related services. [PDF]
, 1995 The Adoptive Parents Association of Ireland would like to thank all the people who, with the.help reassurance and which make this handbook possible. There was much encouragement from the many social workers contacted for information and great help ...
Adoptive Parents Association of Ireland
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Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Oncolytic Adenoviruses Armed with Tumor Necrosis Factor Alpha and Interleukin-2 Enable Successful Adoptive Cell Therapy [PDF]
, 2017 Adoptive cell therapy holds much promise in the treatment of cancer but results in solid tumors have been modest. The notable exception is tumor-infiltrating lymphocyte (TIL) therapy of melanoma, but this approach only works with high-dose ...
João Manuel Santos +25 more
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