Results 31 to 40 of about 2,157,684 (307)

Activation of T lymphocytes for the adoptive immunotherapy of cancer [PDF]

open access: yes, 1994
Background: Adoptive immunotherapy of malignancy involves the passive transfer of antitumor-reactive cells into a host in order to mediate tumor regression.
Shu, Suyu   +7 more
core   +1 more source

M2-like macrophages transplantation protects against the doxorubicin-induced heart failure via mitochondrial transfer

open access: yesBiomaterials Research, 2022
Aims The alternatively activated macrophages have shown a cardioprotective effect in heart failure. However, the effect of M2 adoptive transfer in non-ischemic heart failure is unknown.
Yihai Liu   +4 more
doaj   +1 more source

Genetic modification and effector functions of natural killer cells in acute myeloid leukemia [PDF]

open access: yes, 2006
Acute myeloid leukemia (AML) is characterized by a poor long-term outcome in the majority of patients following conventional treatment with chemotherapy.
Siegler, Uwe
core   +1 more source

Hit Parade for Adoptive Cell Transfer Therapy: The Best T Cells for Superior Clinical Responses [PDF]

open access: yes, 2013
Adoptive cell transfer (ACT) of T cells has great clinical potential, but the numerous variables of this therapy make choices difficult. A new study takes advantage of a novel technology for characterizing the T-cell responses of patients.
Speiser, D.E.   +2 more
core   +1 more source

Stem Cell-Derived Viral Antigen-Specific T Cells Suppress HIV Replication and PD-1 Expression on CD4+ T Cells

open access: yesViruses, 2021
The viral antigen (Ag)-specific CD8+ cytotoxic T lymphocytes (CTLs) derived from pluripotent stem cells (PSCs), i.e., PSC-CTLs, have the ability to suppress the human immunodeficiency virus (HIV) infection.
Mohammad Haque   +8 more
doaj   +1 more source

Improving Tumor Retention of Effector Cells in Adoptive Cell Transfer Therapies by Magnetic Targeting

open access: yesPharmaceutics, 2020
Adoptive cell transfer therapy is a promising anti-tumor immunotherapy in which effector immune cells are transferred to patients to treat tumors. However, one of its main limitations is the inefficient trafficking of inoculated effector cells to the ...
Laura Sanz-Ortega   +2 more
doaj   +1 more source

Neuroprotective effects of ex vivo-expanded regulatory T cells on trimethyltin-induced neurodegeneration in mice

open access: yesJournal of Neuroinflammation, 2022
Background Trimethyltin (TMT) is a potent neurotoxicant that leads to hippocampal neurodegeneration. Regulatory T cells (Tregs) play an important role in maintaining the immune balance in the central nervous system (CNS), but their activities are ...
Seon-Young Park   +6 more
doaj   +1 more source

Adoptive Transfer of Lung Antigen Presenting Cells

open access: yesBio-Protocol, 2017
Our protocol describes adoptive transfer of antigen presenting cells (APCs) isolated from the lungs by enzymatic digestion and magnetic enrichment. This protocol can be used to study APC functions and trafficking.
Xiaofeng Zhou, Bethany Moore
doaj   +1 more source

CD4-helper-independent antiviral function of CD8-positive memory T lymphocytes derived from latently infected donors [PDF]

open access: yes, 1988
The ability of memory T lymphocytes derived from latently infected mice to control murine cytomegalovirus disease in the immunocompromised host was studied by adoptive transfer experiments.
Reddehase, Matthias J.   +4 more
core   +1 more source

Strategies of adoptive T -cell transfer to treat refractory viral infections post allogeneic stem cell transplantation

open access: yesJournal of Hematology & Oncology, 2019
Background Allogeneic hematopoietic stem cell transplantation (HSCT) can expose patients to a transient but marked immunosuppression, during which viral infections are an important cause of morbidity and mortality.
Theresa Kaeuferle   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy