Adoptive transfer of acute lung injury [PDF]
American Journal of Physiology-Lung Cellular and Molecular Physiology, 2000 In this study, we describe a novel adoptive transfer protocol to study acute lung injury in the rat. We show that bronchoalveolar lavage (BAL) cells isolated from rats 5 h after intratracheal administration of lipopolysaccharide (LPS) induce a lung injury when transferred to normal control recipient rats.
M A, Moxley, T L, Baird, J A, Corbett
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Efficacious control of cytomegalovirus infection after long-term depletion of CD8+ T lymphocytes [PDF]
, 1990 Although the relative contribution of different immune effector functions to clearing tissues of cytomegalovirus is controversial, the contribution of CD8+ T lymphocytes has generally been accepted as essential. In this report, we show that under certain
Pavic, Ivica +6 more
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Impact of interleukin-7 on the differentiation and anti-tumor capabilities of CD8+ T cells [PDF]
Egyptian Journal of Cancer and Biomedical Research, 2020 Background: Developing optimal strategies for generating T cells capable of effectively controlling tumors is one of the most important prerequisites for the clinical application of adoptive cell therapies in cancer patients.
Abdelaziz Zidan, Muobarak Tuorkey
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Adoptive transfer of Tregs: A novel strategy for cell-based immunotherapy in spontaneous abortion: Lessons from experimental models [PDF]
, 2021 Since half of the genes are inherited from the paternal side, the maternal immune system has to tolerate the presence of foreign paternal antigens. Regulatory T cells facilitate the development and maintenance of peripheral tissue tolerance of the fetus ...
Abdollahi, Elham +6 more
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Immune cell labelling and tracking: implications for adoptive cell transfer therapies
EJNMMI Radiopharmacy and Chemistry, 2021 Background The understanding of the role of different immune cell subsets that infiltrate tumors can help researchers in developing new targeted immunotherapies to reactivate or reprogram them against cancer.
Filippo Galli +5 more
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Immunodominance of lytic cycle antigens in Epstein-Barr virus-specific CD4+ T cell preparations for therapy. [PDF]
, 2007 Epstein-Barr virus (EBV) is associated with a number of human malignancies. EBV-positive post-transplant lymphoproliferative disease in solid organ and hematopoietic stem cell transplant recipients has been successfully treated by the adoptive transfer ...
Burdach, S. +38 more
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Adoptive Transfer of HIV-Specific Cytotoxic T Lymphocytes [PDF]
, 2000 Several independent observations suggest that cytotoxic T lymphocytes (CTL) are critical for the control of HIV infection. We have studied the adoptive transfer of CTL in three patients with aquired immunodeficiency syndrome (AIDS). In the first patient,
Tan, Rusung
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Frontiers in Immunology, 2023 Efficient intratumoral infiltration of adoptively transferred cells is a significant barrier to effectively treating solid tumors with adoptive cellular transfer (ACT) therapies. Our recent forward genetic, whole-genome screen identified T cell-intrinsic
Vianca V. Vianzon +4 more
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Adoptive transfer of antithyrotropin receptor (TSHR) autoimmunity from TSHR knockout mice to athymic nude mice [PDF]
, 2012 We have recently shown that wild type mice are highly tolerant, whereas thyrotropin receptor (TSHR) knockout (KO) mice are susceptible to immunization with the mouse TSHR, the autoantigen in Graves' disease.
Taguchi, Ryo +13 more
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Combining antiangiogenic therapy with adoptive cell immunotherapy exerts better antitumor effects in non-small cell lung cancer models. [PDF]
PLoS ONE, 2013 INTRODUCTION: Cytokine-induced killer cells (CIK cells) are a heterogeneous subset of ex-vivo expanded T lymphocytes which are characterized with a MHC-unrestricted tumor-killing activity and a mixed T-NK phenotype.
Shujing Shi +5 more
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