Results 1 to 10 of about 2,157,684 (307)

Thy1 retroviral reporters: a versatile platform for congenic background-independent adoptive transfer and CD8+ T cell differentiation studies [PDF]

Frontiers in Immunology
Adoptive T cell transfer remains a fundamental technique for dissecting the molecular mechanisms governing T cell differentiation. A successful adoptive-transfer experiment typically relies on labor-intensive construction of specific congenic mouse ...
Chunlong Liu, Chunling Liu, Jing Zhong, Xiaodi Yang, Xiaodi Yang, Dapeng Wang, Dapeng Wang   +6 more
doaj   +2 more sources

Anti-tumor efficacy of a combination therapy with PD-L1 targeted alpha therapy and adoptive cell transfer of PD-1 deficient melanoma-specific human T-lymphocytes

OncoImmunology, 2021
The optimization of adoptive transfer approaches of anti-tumor T cells requires both the functional improvement of the injected T cells and the modulation of the tumor microenvironment, favoring the recruitment of these T cells and their activation.
L Marotte, M Capitao, C Deleine, T Beauvais, G Cadiou, J. Perrin, M Chérel, E Scotet, Y Guilloux, F Bruchertseifer, A Morgenstern, A Jarry, J. Gaschet, N Labarriere   +13 more
doaj   +2 more sources

Adoptive Transfer of Memory B Cells [PDF]

Bio-Protocol, 2015
The adoptive transfer of antigen-specific B cells into mice that cannot recognize that specific antigen has two main advantages. The first is determining exactly when the B cells were transferred and exposed to antigen.
Griselda Zuccarino-Catania, Mark Shlomchik   +1 more
doaj   +3 more sources

Adoptive Cellular Transfer Immunotherapies for Cancer

Cancer Treatment and Research Communications, 2022
Patients with cancer require efficient treatment approaches as the mortality rate due to their disease is high. Conventional therapies, like chemotherapy and radiation, have severe side effects.
Panagiotis Parsonidis, Ioannis Papasotiriou   +1 more
doaj   +3 more sources

Adoptive Transfer of Isolated Bone Marrow Neutrophils [PDF]

Bio-Protocol, 2012
Adoptive transfer experiments of specific cell populations are widely used methods to assess the role of the injected population on an ongoing process.
Jimena Boari, Eva Rodríguez
doaj   +4 more sources

Efficient T cell adoptive transfer in lymphoreplete hosts mediated by transient activation of Stat5 signaling [PDF]

Molecular Therapy, 2023
Leonardo Ferreira
exaly   +2 more sources

Allogeneic lymphocytes persist and traffic in feral MHC-matched mauritian cynomolgus macaques. [PDF]

PLoS ONE, 2008
Thus far, live attenuated SIV has been the most successful method for vaccinating macaques against pathogenic SIV challenge; however, it is not clear what mechanisms are responsible for this protection.
Justin M Greene, Benjamin J Burwitz, Alex J Blasky, Teresa L Mattila, Jung Joo Hong, Eva G Rakasz, Roger W Wiseman, Kim J Hasenkrug, Pamela J Skinner, Shelby L O'Connor, David H O'Connor   +10 more
doaj   +1 more source

A novel and effective cancer immunotherapy mouse model using antigen-specific B cells selected in vitro. [PDF]

PLoS ONE, 2014
Immunotherapies such as adoptive transfer of T cells or natural killer cells, or monoclonal antibody (MoAb) treatment have recently been recognized as effective means to treat cancer patients.
Tatsuya Moutai, Hideyuki Yamana, Takuya Nojima, Daisuke Kitamura   +3 more
doaj   +1 more source

Adoptive immune transfer from donors offers Anti-HBV protection to HBsAb-negative patients after Allo-HSCT

iScience, 2023
Summary: Adoptive transfer of hepatitis B virus (HBV) immunity may occur following allogeneic hematopoietic stem cell transplantation (allo-HSCT). Here, we investigated the adoptive transfer of HBV immunity in 112 patients without HBV surface antibody ...
Jinhua Ren, QiaoXian Lin, Qi Chen, Jingjing Xu, Dabin Chen, Renli Chen, Kangni Lin, Haojie Zhu, Chenjing Ye, Xiaofeng Luo, Shaozhen Chen, Hui Kong, Qiong Lin, Nan Li, Xu Lin, Zhizhe Chen, Jianda Hu, Ting Yang   +17 more
doaj   +1 more source

Fibrinogen-like protein 2/fibroleukin induces long-term allograft survival in a rat model through regulatory B cells. [PDF]

PLoS ONE, 2015
We previously described that in a rat model of heart transplantation tolerance was dependent on CD8+CD45RClow Tregs that over-expressed fibrinogen-like protein 2 (FGL2)/fibroleukin. Little is known on the immunoregulatory properties of FGL2.
Séverine Bézie, Elodie Picarda, Laurent Tesson, Karine Renaudin, Justine Durand, Séverine Ménoret, Emmanuel Mérieau, Elise Chiffoleau, Carole Guillonneau, Lise Caron, Ignacio Anegon   +10 more
doaj   +1 more source