Results 131 to 140 of about 213,935 (349)

Expression and distribution of adenosine diphosphate-ribosylation factors in the rat kidney111Present address is: Renal Unit & Program in Membrane Biology, Massachusetts General Hospital, Harvard Medical School, 149, 13th Street, 8th Floor, Boston, MA, 02129, USA [PDF]

, 1999
Expression and distribution of adenosine diphosphate-ribosylation factors in the rat kidney.BackgroundAdenosine diphosphate (ADP)-ribosylation factors (ARFs) are small guanosine triphosphatases involved in membrane traffic regulation.
Bendayan, Moïse, Bourgoin, Sylvain, Londoño, Irene, Marshansky, Vladimir, Vinay, Patrick   +4 more
core   +1 more source

Diatom triacylglycerol metabolism: from carbon fixation to lipid droplet degradation

Biological Reviews, EarlyView.
ABSTRACT Diatoms are a prominent microalgae family that has attracted interest for its production of molecules of biotechnological interest. Their fatty acid profile is rich in health‐beneficial omega‐3 eicosapentaenoic acid (EPA). Furthermore, under nutrient‐deprived conditions, many diatom species, notably Phaeodactylum tricornutum, Thalassiosira ...
Victor Murison, Josiane Hérault, Justine Marchand, Lionel Ulmann   +3 more
wiley   +1 more source

The Infinite Hierarchical Factor Regression Model [PDF]

NIPS 2008, 2009
We propose a nonparametric Bayesian factor regression model that accounts for uncertainty in the number of factors, and the relationship between factors. To accomplish this, we propose a sparse variant of the Indian Buffet Process and couple this with a hierarchical model over factors, based on Kingman's coalescent. We apply this model to two problems (
arxiv  

What have we learned from two-pore potassium channels? Their molecular configuration and function in the human heart [PDF]

, 2012
Two-pore domain potassium channels (K2P) control excitability, stabilize the resting membrane potential below firing threshold, and accelerate repolarisation in different cells.
Benyhe, Sándor, Boyett, Marc, Dobrzynski, Halina, Dézsi, László, Erdélyi, Lajos, Papp, Gyula, Szalontai, Balázs, Szüts, Viktória, Varró, András, Vágvölgyi, Csaba, Zhang, Henggui, Ötvös, Ferenc   +11 more
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ADP-ribosylation of arginine [PDF]

, 2010
Arginine adenosine-5′-diphosphoribosylation (ADP-ribosylation) is an enzyme-catalyzed, potentially reversible posttranslational modification, in which the ADP-ribose moiety is transferred from NAD+ to the guanidino moiety of arginine.
A Grahnert, A Ruf, A Sekine, A Zolkiewska, A Zolkiewska, A Zolkiewska, AE Lang, AK Ganesan, AK Ganesan, AK Ganesan, BA Saxty, BD Spangler, C Dolle, C Krebs, C Locht, C Loesberg, CG Goff, CJ Schwab, D Cervantes-Laurean, D Corda, D Tezcan‐Merdol, E Nemoto, F Haag, F Haag, F Koch-Nolte, F Koch-Nolte, F Koch-Nolte, F Koch-Nolte, F Koch-Nolte, F Scheuplein, Friedrich Haag, Friedrich Koch-Nolte, G Glowacki, G Glowacki, G Paone, G Paone, G Timinszky, H Hochmann, H Osago, H Osago, H Otto, H Schluter, H Tsuge, H Zhou, HY Huang, I Carpusca, I Just, J Baysarowich, J Kato, J Menetrey, J Moss, J Moss, J Moss, J Schirmer, J Sun, J Sun, J Vandekerckhove, J Vandekerckhove, J Wesolowski, JR Woodgett, JT Barbieri, K Aktories, K Aktories, K Rikova, LA Stevens, LF Westblade, M Altmeyer, M Kim, M Seman, M Terashima, M Terashima, M Terashima, M Vogelsgesang, Mandy Unger, MK Jacobson, MR Pope, N Dani, N Hara, N Schwarz, P Bannas, P Gonnord, PJ Berti, PR Jungblut, PW Ludden, R Depping, R Jorgensen, R Lupi, R Matsuura, RJ Fieldhouse, S Adriouch, S Han, S Han, S Stubbs, S Till, Sabrina Laing, SM Hengel, SM Margarit, SV Kharadia, T Maehama, T Meyer, W Ohlrogge, Z Zhao   +101 more
core   +2 more sources

Characterization of a Fast Cycling ADP-ribosylation Factor 6 Mutant [PDF]

Journal of Biological Chemistry, 2002
Studies of GTPase function often employ expression of dominant negative or constitutively active mutants. Dominant negative mutants cannot bind GTP and thus cannot be activated. Constitutively active mutants cannot hydrolyze GTP and therefore accumulate a large pool of GTP-bound GTPase. These mutations block the normal cycle of GTP binding, hydrolysis,
openaire   +3 more sources

The Combination of PARP and Topoisomerase 1 Inhibitors Improves Radiation Therapy for Ewing Sarcoma

Cancer Science, EarlyView.
The addition of RT to the combination of TAL plus irinotecan (IRN), a recently evaluated clinical regimen for relapsed pediatric solid tumors, significantly prolonged survival and reduced tumor burden in EWS mouse models. This triplet therapy (TAL + IRN + RT) was feasible and yielded responses in several patients with EWS and may represent a useful ...
Jia Xie, Marcia M. Mellado‐Lagarde, Kaley Blankenship, Debolina Ganguly, Nathaniel R. Twarog, Brandon Bianski, Matthew Kieffer, Stefan Atkinson, Heather Sheppard, Jessica Gartrell, Samuel Cler, Sara M. Federico, Elizabeth A. Stewart, Christopher L. Tinkle, Anang A. Shelat   +14 more
wiley   +1 more source

Analyzing the safety of the parasiticide fungus Mucor circinelloides: first insights on its virulence profile and interactions with the avian gut microbial community

Microbiology Spectrum
Parasiticide fungi are considered an accurate, sustainable, and safe solution for the biocontrol of animal gastrointestinal (GI) parasites. This research provides an initial characterization of the virulence of the native parasiticide fungus Mucor ...
João Lozano, Eva Cunha, Cristina Almeida, Mónica Nunes, Ricardo Dias, Eduardo Vicente, Daniela Sebastião, Sérgio Henriques, Luís Madeira de Carvalho, Adolfo Paz-Silva, Manuela Oliveira   +10 more
doaj   +1 more source

New Pivot Selection for Sparse Symmetric Indefinite Factorization [PDF]

arXiv, 2016
We propose a new pivot selection technique for symmetric indefinite factorization of sparse matrices. Such factorization should maintain both sparsity and numerical stability of the factors, both of which depend solely on the choices of the pivots. Our method is based on the minimum degree algorithm and also considers the stability of the factors at ...
arxiv  

Regulation of mitochondrial DNA replication by macroD1 and ADP-ribosylation [PDF]

, 2021
Mammalian mitochondria, the double-membrane-bound organelles found in most eukaryotic cells contain between 100 and several 100000 copies of mitochondrial DNA (mtDNA).
Söllner, Flavia
core