Results 151 to 160 of about 215,162 (341)
Nine mutations in the switch I and switch II regions of human ADP-ribosylation factor 3 (ARF3) were isolated from loss-of-interaction screens, using two-hybrid assays with three different effectors.
J. Kuai+4 more
semanticscholar +1 more source
Biogenesis and reformation of synaptic vesicles
Abstract figure legend Synaptic vesicle proteins are axonally transported in precursor vesicles (PVs) before conversion into mature synaptic vesicles (SVs) that are reformed by local recycling at synapses. Abstract Communication within the nervous system relies on the calcium‐triggered release of neurotransmitter molecules by exocytosis of synaptic ...
Svenja Bolz, Volker Haucke
wiley +1 more source
On Pinsker factors for Rokhlin entropy [PDF]
In this paper we will prove that any dynamical system posess the unique maximal factor of zero Rokhlin entropy, so-called Pinsker factor. It is proven also, that if the system is ergodic and this factor has no atoms then system is relatively weakly mixing extension of its Pinsker factor.
arxiv
Sphingosine‐1‐phosphate activates LRRC8 volume‐regulated anion channels through Gβγ signalling
Abstract figure legend Sphingosine‐1‐phosphate (S1P) binds to Gi protein‐coupled receptor S1PR1. Upon S1PR1 activation, Gβγ is released from the Gαi‐Gβγ heterotrimer, allowing it to recruit phospholipase Cβ (PLCβ) to the plasma membrane. PLCβ cleaves phosphatidylinositol‐4,5‐bisphosphate (PIP2) into inositol trisphosphate (IP3) and diacylglycerol (DAG).
Yulia Kostritskaia+4 more
wiley +1 more source
New plans orthogonal through the block factor [PDF]
In the present paper we construct plans orthogonal through the block factor (POTBs). We describe procedures for adding blocks as well as factors to an initial plan and thus generate a bigger plan. Using these procedures we construct POTBs for symmetrical experiments with factors having three or more levels.
arxiv
NAD+-dependent post-translational modification of Escherichia coli glyceraldehyde-3-phosphate dehydrogenase [PDF]
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a multifunctional housekeeping protein reported to be a target of several covalent modifications in many organisms.
Josefa Badia+4 more
core +3 more sources
Abstract CEP162, a 162‐kDa centrosome protein, is a crucial centrosomal adapter, mediating cell differentiation and polarization. CEP162 maintains mitosis by dynamically stabilizing microtubules. CEP162 promotes the transition zone (TZ) assembly in the basal body through interaction with CEP131, CEP290, and axoneme microtubules as well as the distal ...
Jun Yin+7 more
wiley +1 more source
Deep Factorization for Speech Signal [PDF]
Speech signals are complex intermingling of various informative factors, and this information blending makes decoding any of the individual factors extremely difficult. A natural idea is to factorize each speech frame into independent factors, though it turns out to be even more difficult than decoding each individual factor.
arxiv
Lactylation: From Homeostasis to Pathological Implications and Therapeutic Strategies
Lactylation, a novel post‐translational modification derived from lactate metabolism, plays a critical role in cellular homeostasis and disease pathogenesis. Under physiological conditions, lactylation regulates gene expression, immune responses, and metabolic adaptation. However, dysregulated lactylation is implicated in various pathological processes,
Xi Chen+6 more
wiley +1 more source
Invariance properties of thematic factorizations of matrix functions [PDF]
We study the problem of invariance of indices of thematic factorizations. Such factorizations were introduced in [PY1] for studying superoptimal approximation by bounded analytic matrix functions. As shown in [PY1], the indices may depend on the choice of a thematic factorization. We introduce the notion of a monotone thematic factorization.
arxiv