Results 151 to 160 of about 45,518 (211)

ADP-ribosylation of NuMA promotes DNA single-strand break repair and transcription.

Cell Rep
Abugable AA, Liao C, Antar S, Dowson M, El-Khamisy SF.   +4 more
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A FRET-based high-throughput screening assay for the discovery of Mycobacterium tuberculosis DNA ADP-ribosylglycohydrolase DarG inhibitors

Duong MTH, Lu Y, Ahel I, Lehtiö L.
europepmc   +1 more source

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TcArf1: a Trypanosoma cruzi ADP-ribosylation factor

Parasitology Research, 2003
Arfs (ADP-ribosylation factors) are conserved GTP-binding proteins involved in the control of coatomers assembling in budding vesicles in the eukaryotic secretory pathway and during some endocytic events. Here, we describe the gene for an Arf-homologue from the unicellular kinetoplastid parasite Trypanosoma cruzi, named TcArf1.
Alexandre, de Sá-Freire, José Luciano, Nepomuceno-Silva, Júlio César, da Paixão, Sérgio Maurício, de Mendonça, Luiz Dione Barbosa, de Melo, Ulisses Gazos, Lopes   +5 more
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Assays of ADP-Ribosylation factor Function

2002
ADP-ribosylation factors (ARFs) comprise a family of 20-kDa GTPases first identified as the protein cofactor required for the ADP ribosylation of the G s α protein, catalyzed by the A 1 subunits of the bacterial toxins cholera toxin (CT) and Escherichia colt heat-labile toxin (UF).
Jun, Kuai, Richard A, Kahn
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Cellular ADP-ribosylation of Elongation Factor 2

Molecular and Cellular Biochemistry, 1994
A cellular ADP-ribosyltransferase activity has been found in a variety of animals and tissues. The enzyme transfers ADP-ribose from NAD to elongation factor 2, inactivating the factor and thus inhibiting in vitro protein synthesis. Although, the mechanism of action of the cellular enzyme appears similar to diphtheria toxin and Pseudomonas exotoxin A ...
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Molecular Characterization of ADP-Ribosylation Factors

1993
Cholera toxin (CT) is largely responsible for the pathogenesis of cholera, a devastating diarrheal disease characterized by marked abnormalities in fluid and electrolyte flux (Carpenter 1980; Finkelstein 1973; Kelly 1986). The toxin, a product of Vibrio cholerae, is an oligomeric protein composed of one A subunit (CTA) of about 29kDa and five B ...
J. Moss, M. Vaughan
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ADP-ribosylation factor (ARF)

1994
Abstract Cloned ARF cDNA predicts a protein with a glycine at this position. Each of the three human ARF cDNAs hARF11314 (accession number P10947), hARF315 (accession number P16587), and hARF4,3,15 (accession numbers P18085, P21371) encode proteins of 180 or 181 amino acids with predicted molecular masses of 21-22 kDa.
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ADP-ribosylation Factors Protein Activators of Cholera Toxin

1993
Publisher Summary The toxins alter the activity of the guanine nucleotide-binding proteins (G proteins) by catalyzing the transfer of the ADP-ribose moiety of NAD to a critical amino acid in the a subunit. This ADP-ribosylation reaction results in either activation (e.g., cholera toxin, E.
J, Moss, M, Vaughan
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ADP-Ribosylation Factor-1 Is Sensitive to N-Ethylmaleimide

Journal of Biochemistry, 1998
The treatment of normal rat kidney cells with N-ethylmaleimide caused the release of beta-COP, a component of coatomer, from the Golgi apparatus without causing disassembly of the organelle. The release of beta-COP, which was not due to depolymerization of microtubules, was markedly blocked by the activation of GTP-binding proteins by aluminum fluoride
T, Yamaguchi, K, Nakayama, K, Hatsuzawa, K, Tani, M, Himeno, M, Tagaya   +5 more
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