The contribution of epigenetics in Sjögren's Syndrome. [PDF]
International audience: Sjögren's syndrome (SS) is a chronic autoimmune epithelitis that combines exocrine gland dysfunctions and lymphocytic infiltrations.
Athanasios G Tzioufas +8 more
core +4 more sources
Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics [PDF]
Liquid-liquid phase separation (LLPS) of RNA-binding proteins plays an important role in the formation of multiple membrane-less organelles involved in RNA metabolism, including stress granules.
Abigail M. Janke +90 more
core +4 more sources
Glyphosate’s Suppression of Cytochrome P450 Enzymes and Amino Acid Biosynthesis by the Gut Microbiome: Pathways to Modern Diseases [PDF]
Glyphosate, the active ingredient in Roundup[superscript ®], is the most popular herbicide used worldwide. The industry asserts it is minimally toxic to humans, but here we argue otherwise.
Samsel, Anthony, Seneff, Stephanie
core +2 more sources
Bacterial toxin ADP-ribosyltransferases, e.g. diphtheria toxin (DT) and pertussis toxin, have in common consensus sequences involved in catalytic activity, which are localized to three regions. Region I is notable for a histidine or arginine; region II, approximately 50-75 amino acids downstream, is rich in aromatic/hydrophobic amino acids; and region ...
T, Takada, K, Iida, J, Moss
openaire +1 more source
Functions of Alphavirus Macrodomain-containing protein nsP3 [PDF]
Alphaviruses are positive strand RNA viruses that replicate in association with cellular membranes. The viral RNA replication complex consists of four non-structural proteins nsP1-nsP4 which are essential for viral replication.
Neuvonen, Maarit
core
Inputs and outputs of poly(ADP-ribosyl)ation: relevance to oxidative stress [PDF]
Hegedűs, Csaba, Virág, László
core +1 more source
The evaluation of the activity of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase under different patho-physiological conditions : a combined enzyme histochemical and biochemical approach [PDF]
This thesis is based on a series of metabolic studies conducted on material obtained from human and experimental animal tissues and cells. The studies are essentially enzyme histochemical complemented when thought necessary with biochemical ...
Elias, E.A. (Ezzat), Heul, R.O. van der
core
Expression of HDAC1 in leukemia cells [PDF]
Histone deacetylases (HDACs) is an enzyme which removes the acetyl group and thus completes the reversible modification of histone by acetylation.
Sethi, Himani
core
Poly(ADP-ribose) polymerases as modulators of mitochondrial activity [PDF]
Bai, Péter +4 more
core +1 more source

