Results 101 to 110 of about 15,419 (219)

AIRP onlus partecipa al 1° Summit Europeo dedicato ai pazienti affetti da ADPKD

Giornale di Clinica Nefrologia e Dialisi, 2019
On Saturday the16th March 2019, AIRP participated at the 1st European ADPKD Patient Summit – a unique event designed to promote patient-centred care by providing an interactive forum for patients and experts to discuss ADPKD care, research and advocacy ...
Flavia Galletti, Franco Martini
doaj   +1 more source

Revisiting racial differences in ESRD due to ADPKD in the United States

BMC Nephrology, 2019
IntroductionAutosomal dominant polycystic kidney disease (ADPKD) affects all races. Whether the progression of ADPKD varies by race remains unclear.MethodsIn this retrospective cohort study from 2004 to 2013 non-Hispanic blacks and non-Hispanic whites of
E. Murphy, F. Dai, K. L. Blount, Madeline L Droher, Lauren Liberti, D. Crews, N. Dahl   +6 more
semanticscholar   +1 more source

Canonical Wnt inhibitors ameliorate cystogenesis in a mouse ortholog of human ADPKD.

JCI Insight, 2018
Autosomal dominant polycystic kidney disease (ADPKD) can be caused by mutations in the PKD1 or PKD2 genes. The PKD1 gene product is a Wnt cell-surface receptor. We previously showed that a lack of the PKD2 gene product, PC2, increases β-catenin signaling
Ao Li, Yuchen Xu, Song Fan, Jialin Meng, Xufeng Shen, Qian Xiao, Yuan Li, Li Zhang, Xiansheng Zhang, Guan-qing Wu, C. Liang, Dianqing Wu   +11 more
semanticscholar   +1 more source

Heterogeneous Cardiovascular Profiles in CKD: ADPKD Versus non-ADPKD

Kidney International Reports, 2022
Au, Eric H.K., Gupta, Aditi
openaire   +2 more sources

Profiling of miRNAs and target genes related to cystogenesis in ADPKD mouse models

Scientific Reports, 2017
Autosomal polycystic kidney disease (ADPKD) is a common inherited renal disease characterized by the development of numerous fluid-filled cysts in both kidneys.
Yu mi Woo, Do Yeon Kim, Namjin Koo, Yong-Min Kim, Sunyoung Lee, Je Yeong Ko, Yubin Shin, Bo Hye Kim, Hyowon Mun, Seonju Choi, Eun Ji Lee, Jeong-Oh Shin, E. Park, J. Bok, Jong Hoon Park   +14 more
semanticscholar   +1 more source

Overview of ADPKD in Pregnancy

Kidney International Reports
Autosomal dominant polycystic kidney disease (ADPKD) is a systemic disorder that often affects patients in their third to fifth decades of life and is characterized by kidney cysts, chronic kidney disease (CKD), hypertension, and hepatic cysts. The development of clinical symptoms often coincides with childbearing years. Consequently, there are several
Ruth E. Campbell, Charles L. Edelstein, Michel Chonchol   +2 more
openaire   +3 more sources

Rapamycin treatment dose‐dependently improves the cystic kidney in a new ADPKD mouse model via the mTORC1 and cell‐cycle‐associated CDK1/cyclin axis

Journal of Cellular and Molecular Medicine, 2017
Although translational research into autosomal dominant polycystic kidney disease (ADPKD) and its pathogenesis has made considerable progress, there is presently lack of standardized animal model for preclinical trials.
Ao Li, Song Fan, Yuchen Xu, Jialin Meng, Xufeng Shen, Jun Mao, Li Zhang, Xiansheng Zhang, G. Moeckel, Dianqing Wu, Guan-qing Wu, C. Liang   +11 more
semanticscholar   +1 more source

Phosphorylation, protein kinases and ADPKD

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2011
Autosomal dominant polycystic kidney disease (ADPKD) is a genetic disease characterized by renal cyst formation and caused by mutations in the PKD1 and PKD2 genes, which encode polycystin-1(PC-1) and -2 (PC-2) proteins, respectively. PC-1 is a large plasma membrane receptor involved in the regulation of several biological functions and signaling ...
openaire   +2 more sources

Fluoroquinolone-Associated Tendinopathy: An Important Complication of Cyst Infection Management in Polycystic Kidney Disease

International Medical Case Reports Journal
Miwa Kaneko, Tetsu Akimoto, Daisuke Nagata Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Tochigi, JapanCorrespondence: Tetsu Akimoto, Division of Nephrology, Department of Internal Medicine, Jichi Medical University ...
Kaneko M, Akimoto T, Nagata D
doaj  

Unusual familial cystic kidney disease: combining fine radiologic and genetic evaluation to solve the case

BMC Nephrology
Background Autosomal dominant polycystic kidney disease (ADPKD) is the most prevalent hereditary kidney disease, characterized by enlarged kidneys with numerous cysts, high blood pressure, and a variety of extrarenal complications.
Sylvain Bodard, Rim Nabbout, Olivier Hélénon, Bertrand Knebelmann   +3 more
doaj   +1 more source