Results 101 to 110 of about 12,370 (174)

Cyst initiation, cyst expansion and progression in ADPKD [PDF]

, 2012
Autosomal dominant polycystic kidney disease (ADPKD) is characterized by large fluid-filled cysts and progressive deterioration of renal function necessitating renal replacement therapy. In this thesis different phases of ADPKD were studied.
Happé, H.
core  

Repurposing calcium-sensing receptor activator drug cinacalcet for ADPKD treatment.

ADPKD is characterized by progressive cyst formation and enlargement leading to kidney failure. Tolvaptan is currently the only FDA-approved treatment for ADPKD; however, it can cause serious adverse effects including hepatotoxicity.
Chhetri, Parth, Cil, Onur, Yottasan, Pattareeya, Chu, Tifany   +3 more
core   +1 more source

Arterial Function Worsens Faster than Renal Function in Autosomal Dominant Polycystic Kidney Disease

Turkish Journal of Nephrology, 2019
OBJECTIVE: Early arterial stiffness has been shown in autosomal dominant polycystic kidney disease (ADPKD) patients with preserved renal function. However, to our knowledge, no prospective study evaluated changes in arterial functions in patients with ...
Abdülmecit YILDIZ, Alparslan ERSOY, Saim SAĞ, Ayşegül ORUÇ, Ercan ÇİĞİLLİ, Yavuz AYAR, Sümeyye GÜLLÜLÜ, Cuma Bülent GÜL   +7 more
doaj  

[ADPKD: predictors of Renal Disease progression]

, 2016
Factors predicting rapid progression of kidney disease in ADPKD can be divided into genetic (non-modifiable) and clinical (modifiable) risk factors.
SCOLARI, Francesco, TERLIZZI, VINCENZO, DALLERA, Nadia, SALETTI, ARIANNA, Izzi, Claudia   +4 more
core  

Incremental health care resource utilization and expenditures associated with autosomal dominant polycystic kidney disease

ClinicoEconomics and Outcomes Research, 2018
Neeraj N Iyer,1 Nicholas J Vendetti,2 Daniel I Levy,3 Jack Mardekian,4 Marko A Mychaskiw,2 Joseph Thomas III1 1Regenstrief Center for Healthcare Engineering and Center for Health Outcomes Research and Policy, College of Pharmacy, Purdue University, West ...
Iyer NN, Vendetti NJ, Levy DI, Mardekian J, Mychaskiw MA, Thomas III J   +5 more
doaj  

Renal denervation in ADPKD: an exceptional case

, 2014
Sympathetic overactivity plays a crucial role in the genesis and aggravation of arterial hypertension in patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD).
Marchetiello Cristina, Pisani Antonio, Petrillo Fortunato, Riccio Eleonora, Migliaccio Silvia, Di Nuzzi Antonella, Mancini Antonio   +6 more
core  

Evidence for a tubular basement membrane-cilia connection in autosomal dominant polycystic kidney disease pathogenesis. [PDF]

J Clin Invest
Sussman CR, Harris PC.
europepmc   +1 more source

Association Between Tolvaptan Exposure and Venous Thromboembolism Risk in ADPKD: A Real-World Propensity-Matched EHR Study. [PDF]

Nephrology (Carlton)
Chen TP, Tsai SF.
europepmc   +1 more source

Autosomal Dominant Polycystic Kidney Disease Presenting as a Painless Epigastric Mass: A Case Report. [PDF]

Am J Case Rep
Zaulkafali TA, Zainal-Abidin ANI, Peter AB, Mohamed-Yassin MS.   +3 more
europepmc   +1 more source

Modeling Complex Developmental Disease: The Case of Polycystic Kidney Disease. [PDF]

J Dev Biol
DeLoriea J, Casey C, Shearer L, Chen V, Bryant A, Gamberi C.   +5 more
europepmc   +1 more source