Results 11 to 20 of about 12,330 (202)

A cross-consortium, stakeholder-driven model for implementing a modern electronic data capture and submission system across the Alzheimer's Disease Research Centers Program. [PDF]

Alzheimers Dement
Abstract INTRODUCTION The National Alzheimer's Coordinating Center (NACC) and Alzheimer's Disease Research Center (ADRC) Program advances dementia research by collecting and sharing standardized, longitudinal data, including the Uniform Data Set with the global research community. To modernize workflow and accelerate the availability of analyzable data,
Biber S, Gothard S, Murchison CF, McLeod L, Gauthreaux K, HewaNadungodage C, Cheng E, Welsch J, Culhane JE, Yasuda S, Stockwell H, Allimatti S, Bauer M, Reader JM, Kukull W, Zozus M, Das S.   +16 more
europepmc   +2 more sources

Integrating real-world data with gold-standard longitudinal clinical and genomic data to advance precision medicine for the Alzheimer's Disease Research Center Program and beyond: a proof-of-concept data platform. [PDF]

Alzheimers Dement
Abstract INTRODUCTION Integrating real‐world data (RWD) with clinical research datasets creates more complete, context‐rich resources to drive discovery and enable precision medicine in Alzheimer's disease and related dementias. The National Alzheimer's Coordinating Center conducted a proof‐of‐concept (POC) project to link its longitudinal Uniform Data
Biber S, Culhane JE, Prado MG, Mathew S, Burrola-Mendez Y, West II, Van Heiden S, Phuong J, Allimatti S, Lane LG, Moulder KL, Hale BK, Kuzma A, Wang LS, Gao S, Lai A, Natarajan K, Wang S, Morris JC, Noble JM, Mooney SD, Kukull W, Saykin AJ, Stephens KA.   +23 more
europepmc   +2 more sources

A parameter formula connecting PID and ADRC [PDF]

Science China Information Sciences, 2020
This paper presents a parameter formula connecting the well-known proportional-integralderivative (PID) control and the active disturbance rejection control (ADRC). On the one hand, this formula gives a quantitative lower bound to the bandwidth of the extended state observer (ESO) used in ADRC, implying that the ESO is not necessarily of high gain.
Zhong, Sheng, Huang, Yi, Guo, Lei
openaire   +2 more sources

Geographic proximity, neuropathology and ADRC brain donation [PDF]

Alzheimer's & Dementia, 2021
AbstractBackgroundDiverse representation is a known challenge in Alzheimer’s disease research recruitment. Geographic proximity to an Alzheimer’s Disease Research Center (ADRC) may be a factor in brain donation. Whether those donating living closer to a center differ in terms of their social and biological characteristics to those living farther away ...
W Ryan Powell, Megan Zuelsdorff, Nathaniel A Chin, William R Buckingham, Robert A Rissman, Barbara B Bendlin, Amy J Kind   +6 more
openaire   +1 more source

Influences of cycle facilities on cycling to work

International Journal of Population Data Science, 2018
Background In recent years, promoting cycling as a means of transport has been put on multiple policy agendas, including health, transport and climate change. Provision of cycling facilities is important in promotion of bicycle use. However, there are no
Zhiqiang Feng, Chris Dibben
doaj   +1 more source

Effect of age, ethnicity, sex, cognitive status and APOE genotype on amyloid load and the threshold for amyloid positivity

NeuroImage: Clinical, 2019
The threshold for amyloid positivity by visual assessment on PET has been validated by comparison to amyloid load measured histopathologically and biochemically at post mortem.
R. Duara, D.A. Loewenstein, G. Lizarraga, M. Adjouadi, W.W. Barker, M.T. Greig-Custo, M. Rosselli, A. Penate, Y.F. Shea, R. Behar, A. Ollarves, C. Robayo, K. Hanson, M. Marsiske, S. Burke, N. Ertekin-Taner, D. Vaillancourt, S. De Santi, T. Golde, DeKosky ST   +19 more
doaj   +1 more source

Analysis of neurodegenerative Mendelian genes in clinically diagnosed Alzheimer disease [PDF]

, 2017
Alzheimer disease (AD), Frontotemporal lobar degeneration (FTD), Amyotrophic lateral sclerosis (ALS) and Parkinson disease (PD) have a certain degree of clinical, pathological and molecular overlap.
Alexandra Medvedeva, Alison Goate, Ben Saef, Carlos Cruchaga, Joanne Norton, John C. Morris, John P. Budde, Jong Hun Kim, Jorge Del-Aguila, Kathleen Black, Laura Ibañez, Maria Victoria Fernández, null null, null null, Oscar Harari, Rachel Chasse, Umber Dube, Yuetiva Deming   +17 more
core   +4 more sources

Impact of the COVID-19 pandemic on commencement of psychotropic medications in Northern Ireland: a population-wide, administrative data linkage study.

International Journal of Population Data Science, 2022
Objectives This study aimed to explore changes in commencement of psychotropic medications in first 20 months of the pandemic and associated restrictions in Northern Ireland (NI).
Lisa Kent, Dermot O'Reilly, Aideen Maguire   +2 more
doaj   +1 more source

The application of a new PID autotuning method for the steam/water loop in large scale ships [PDF]

, 2020
In large scale ships, the most used controllers for the steam/water loop are still the proportional-integral-derivative (PID) controllers. However, the tuning rules for the PID parameters are based on empirical knowledge and the performance for the loops
De Keyser, Robain, Ionescu, Clara-Mihaela, Liu, Sheng, Zhao, Shiquan   +3 more
core   +1 more source

Tuning and implementation variants of discrete-time ADRC

Control Theory and Technology, 2023
Practical implementations of active disturbance rejection control (ADRC) will almost always take place in discretized form. Since applications may have quite different needs regarding their discrete-time controllers, this article summarizes and extends the available set of ADRC implementations to provide a suitable variant for as many as possible use ...
Herbst, Gernot, Madonski, Rafal
openaire   +3 more sources