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An adrenal incidentaloma is now established as a common endocrine diagnosis that requires a multidisciplinary approach for effective management. The majority of patients can be reassured and discharged, but a personalized approach based upon image ...
M. Sherlock+6 more
semanticscholar +4 more sources
Glucocorticoid replacement therapy, available since the 1950s, has prolonged the survival of patients with adrenal insufficiency. However, adrenal crises, which are life-threatening medical emergencies, still develop in many affected patients.
Falhammar, Henrik+2 more
core +7 more sources
Adrenal crisis and mortality rate in adrenal insufficiency and congenital adrenal hyperplasia [PDF]
Primary adrenal insufficiency (PAI) is characterized by the inability of the adrenal cortex to produce sufficient amounts of glucocorticoids and/or mineralocorticoids. Addison's disease (AD) and congenital adrenal hyperplasia (CAH) are the most frequent disorders in adults and children, respectively. Despite the diagnostic advances and the availability
Lia Mesquita Lousada+2 more
openaire +7 more sources
Overview of the 2022 WHO Classification of Adrenal Cortical Tumors
The new WHO classification of adrenal cortical proliferations reflects translational advances in the fields of endocrine pathology, oncology and molecular biology.
O. Mete+6 more
semanticscholar +1 more source
Adrenal insufficiency with enlarged adrenals [PDF]
Five patients with adrenal insufficiency and large adrenal glands at presentation are reported. Addison's disease was due to adrenal tuberculosis in three patients, with important changes in adrenal configuration on CT reflecting the natural history of the disease.
Efremidis, S. C.+5 more
openaire +3 more sources
Hyperplasia or neoplasia of the adrenal cortex produces aldosterone excess (aldosteronism), hypercortisolism (Cushing’s syndrome), virilism (adreno-genital syndrome), or a mixture of these, according to whether the cells that produce mineralocorticoids, glucocorticoids, or sex hormones, respectively, are in relative excess.
Luis A. Ayala+2 more
openaire +4 more sources
ObjectiveThe result interpretation of the captopril challenge test (CCT) for the diagnosis of primary aldosteronism (PA) is not standardized. Superiorities of different indexes in the CCT have not been fully investigated.
Qiao Xiang+7 more
doaj +1 more source
The hypothalamic-pituitary-adrenal axis is a complex system of neuroendocrine pathways and feedback loops that function to maintain physiological homeostasis.
J. A. Sheng+6 more
semanticscholar +1 more source
Background There is an increasing number of cases of aldosterone- and cortisol-producing adenomas (A/CPAs) reported in the context of primary aldosteronism (PA).
Hongjiao Gao+5 more
doaj +1 more source
The assessment of the impact of chemotherapies on in vitro spermatogenesis in experimental models is required before considering the application of this fertility restoration strategy to prepubertal boys who received these treatments before testicular ...
Marion Delessard+7 more
doaj +1 more source