Results 41 to 50 of about 345,446 (318)

Steroid stewardship

Indian Journal of Endocrinology and Metabolism, 2022
Steroid stewardship is the systematic effort to prescribe and monitor glucocorticoids in a rational manner, while balancing benefit and potential risk, in patients who require this therapy.
Sanjay Kalra, Ashok Kumar, Rakesh Sahay
doaj   +1 more source

Severe loss-of-function mutations in the adrenocorticotropin receptor (ACTHR, MC2R) can be found in patients diagnosed with salt-losing adrenal hypoplasia [PDF]

, 2007
Objective Familial glucocorticoid deficiency type I (FGD1) is a rare form of primary adrenal insufficiency resulting from recessive mutations in the ACTH receptor (MC2R, MC2R).
Hindmarsh, PC, Dattani, MT, Achermann, JC, Metherell, LA, Al-Ali, M, Brain, CE, Alzyoud, M, Clark, AJ, Lin, L, Clark, AJL   +9 more
core   +1 more source

Medical Treatment of Cushing’s Syndrome [PDF]

Endocrinology and Metabolism
Endogenous Cushing’s syndrome (CS) refers to the manifestations of chronic cortisol excess. This rare disease is associated with multiple comorbidities, impaired quality of life, and increased mortality.
Laurence Guignat, Jerome Bertherat
doaj   +1 more source

Hypothalamic-Pituitary-Adrenal (HPA) Axis Functioning in Overtraining Syndrome: Findings from Endocrine and Metabolic Responses on Overtraining Syndrome (EROS)—EROS-HPA Axis

Sports Medicine - Open, 2017
Background Overtraining syndrome (OTS) results from excessive training load without adequate recovery and leads to decreased performance and fatigue. The pathophysiology of OTS in athletes is not fully understood, which makes accurate diagnosis difficult.
Flavio A. Cadegiani, Claudio E. Kater
doaj   +1 more source

Distinguishing between metastatic and benign adrenal masses in patients with extra-adrenal malignancies

Frontiers in Endocrinology, 2022
Background and ObjectivesThe adrenal gland is a common organ involved in metastasis. This study aimed to compare adrenal metastases (AMs) and adrenal benign masses (ABMs) of patients with extra-adrenal malignancies during the staging or follow-up ...
Jinchao Chen, Yedie He, Xiaowei Zeng, Shaoxing Zhu, Fangyin Li   +4 more
doaj   +1 more source

An alternate translation initiation site circumvents an amino-terminal DAX1 nonsense mutation leading to a mild form of X-linked adrenal hypoplasia congenita [PDF]

, 2003
Mutations in DAX1 [dosage-sensitive sex reversal-adrenal hypoplasia congenita (AHC) critical region on the X chromosome gene 1; NROB1] cause X-linked AHC, a disease characterized by primary adrenal failure in infancy or childhood and reproductive ...
Beck-Peccoz, P, J. L. Jameson, A. Spada, Spada, A, G. Mantovani, Weiss, J, P. Beck-Peccoz, Ozisik, G, L. Persani, Achermann, JC, Mantovani, G, J. C. Achermann, J. Weiss, Persani, L, Jameson, JL, G. Ozisik   +15 more
core   +1 more source

Pheochromocytoma/Paraganglioma (PPGL): A Misdiagnosed Cause of Hypertension during Pregnancy

Case Reports in Obstetrics and Gynecology
Hypertension (HT) during pregnancy is not an infrequent obstetric problem, reaching a prevalence of 5-10%. This condition is highly associated with both maternal and fetal complications if not precisely diagnosed and managed.
Rafael Buck Giorgi, Priscila Teixeira Aroucha, Thalissa M. Favreto, Micaela F. Montero, Julia M. F. Velloni, Ilana Korkes, Elisa Napolitano Ferreira, Caroline Olivati, Jose Viana Lima, Claudio E. Kater, Flavia A. Costa-Barbosa   +10 more
doaj   +1 more source

Preclinical Cushing's syndrome in adrenal incidentalomas [PDF]

, 1992
Adrenal tumors are usually diagnosed by clinical symptoms of hormone excess. The increasing use of ultrasound and computed tomography results in the detection of a substantial number of incidentally discovered adrenal tumors.
Winkelmann, W., Saeger, W., Krestin, G. P., Nieke, J., Allolio, B., Reincke, Martin   +5 more
core  

Effects of suckling on hypothalamic-pituitary-adrenal axis responses to psychosocial stress in postpartum lactating women [PDF]

, 2001
In several studies lactation has been shown to be associated with a hypothalamic-pituitary-adrenal axis hyporesponsiveness to physical and psychological stressors. As it is not known whether the marked blunting of endocrine stress reactivity in women can
Heinrichs, M., Neumann, Inga, Hellhammer, Dirk H, Wagner, Sabine, Ehlert, Ulrike; https://orcid.org/, Ehlert, U., Neumann, I., Ehlert, Ulrike, Hellhammer, D. H., Kirschbaum, Clemens, M. Heinrichs, Heinrichs, Markus, Meinlschmidt, G., Wagner, S., Kirschbaum, C., Meinlschmidt, Gunther, Hellhammer, Dirk H.   +16 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source