Results 61 to 70 of about 378,748 (310)

Severe combined adrenal and gonadal deficiency caused by novel mutations in the cholesterol side chain cleavage enzyme, P450scc [PDF]

, 2008
Context: Mitochondrial cytochrome P450scc converts cholesterol to pregnenolone in all steroidogenic tissues. Although progesterone production from the fetally-derived placenta is necessary to maintain pregnancy to term, four patients with mutations in ...
Huang, NW, Achermann, JC, Lin, L, Kim, CJ, Miller, WL, Quigley, CA, AvRuskin, TW   +6 more
core  

Effects of suckling on hypothalamic-pituitary-adrenal axis responses to psychosocial stress in postpartum lactating women [PDF]

, 2001
In several studies lactation has been shown to be associated with a hypothalamic-pituitary-adrenal axis hyporesponsiveness to physical and psychological stressors. As it is not known whether the marked blunting of endocrine stress reactivity in women can
Heinrichs, M., Neumann, Inga, Hellhammer, Dirk H, Wagner, Sabine, Ehlert, Ulrike; https://orcid.org/, Ehlert, U., Neumann, I., Ehlert, Ulrike, Hellhammer, D. H., Kirschbaum, Clemens, M. Heinrichs, Heinrichs, Markus, Meinlschmidt, G., Wagner, S., Kirschbaum, C., Meinlschmidt, Gunther, Hellhammer, Dirk H.   +16 more
core   +1 more source

Multi‐Component Functionalized Bifidobacterium Longum Hydrogel for Multi‐Target Integrated Therapy of Colitis‐Associated Anxiety and Depression

Advanced Science, EarlyView.
A pH/MMP dual‐responsive Bifidobacterium longum (BL) hydrogel (INPs@BL@Gel) functionalized with baicalin, tyrosine, and inulin is constructed. It enables gastric protection, inflammation‐targeted release, and prolonged intestinal colonization. By remodeling gut microbiota, elevating beneficial neuroactive metabolites (homovanillic acid, short‐chain ...
Shuo Zhang, Yujie Zhang, Jiansheng He, Shunlian Li, Qingyan Ma, Qiao Li, Yudan Zhang, Yiyang Wang, Shaobo Ma, Songyan Jin, Chune Li, Xueyong Xie, Hang Zhang, Junze Deng, Xueqin Song, Daocheng Wu, Xiancang Ma, Feng Zhu   +17 more
wiley   +1 more source

Adrenal incidentaloma in neurofibromatosis type 1 [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2008
INTRODUCTION Neurofibromatosis type 1 is one of the most common genetically transmitted diseases with a high index of spontaneous mutations and extremely varied and unpredictable clinical manifestations.
Tančić-Gajić Milina, Vujović Svetlana, Tatić Svetislav, Stojanović Miloš, Ivović Miomira, Drezgić Milka   +5 more
doaj   +1 more source

Integrative Omics Analysis Reveals the Regulation of Hypoxia Tolerance in Large Yellow Croaker (Larimichthys crocea) via the Lipoic Acid Synthase (lias) Gene

Advanced Science, EarlyView.
Lipoic acid synthase (lias) can regulate α‐KG levels through lipoylation, thereby negatively regulating HIF‐1α protein levels via PHD under hypoixa. The Hap2 allele of lias exhibits lower expression levels than Hap1, leading to the accumulation of more HIF‐1α protein and thereby enhancing hypoxia tolerance. ABSTRACT Hypoxia stress seriously affects the
Jie Ding, Songpeng Jia, Ran Meng, Xuelei Wang, Xiongfei Wu, Weiliang Shen, Yibo Zhang, Junquan Zhu   +7 more
wiley   +1 more source

Case Report: Adrenal Epithelial Cyst in an 11-Year-Old Leptailurus Serval

Frontiers in Veterinary Science, 2022
Case DescriptionA serval (Leptailurus serval) presented for progressive enlargement of the right adrenal gland, which had been found incidentally on abdominal ultrasound 2 years previously and upon subsequent ultrasound examinations enlarged ...
Sacha L. Devereux, Wendy I. Baltzer, Susan A. Piripi, Mark C. Owen   +3 more
doaj   +1 more source

Persistent expression of BMP-4 in embryonic chick adrenal cortical cells and its role in chromaffin cell development [PDF]

, 2008
Background: Adrenal chromaffin cells and sympathetic neurons both originate from the neural crest, yet signals that trigger chromaffin development remain elusive.
Huber, Katrin, Halbach Oliver, Kalcheim Chaya, Krispin, S., Krispin Shlomi, Huber, K., Oliver von Bohlen und Halbach, Hermann Rohrer, Unsicker, K., Rohrer, H., Aylin Franke, Shlomi Krispin, Franke Aylin, Ernsberger, U., Unsicker, Klaus, Brühl, Barbara, Huber Katrin, Schober Andreas, Ernsberger Uwe, Chaya Kalcheim, Barbara Brühl, Klaus Unsicker, von Bohlen und Halbach, O., Franke, Aylin, Brühl Barbara, Bohlen und Halbach, Oliver von, Schober, A., Ernsberger, Uwe, Kalcheim, Chaya, Rohrer, Hermann, Rohrer Hermann, Andreas Schober, Schober, Andreas, Krispin, Shlomi, Unsicker Klaus, Brühl, B., Kalcheim, C., Franke, A., Katrin Huber, Uwe Ernsberger   +39 more
core   +1 more source

Paternal Sperm Gnas‐ICR Epigenetic Programming Contributes to PPP‐Like Phenotypes in Female Offspring

Advanced Science, EarlyView.
A paternal glucocorticoid–sperm Gnas‐ICR axis is linked to ovarian endocrine programming in female offspring. Paternal preconception caffeine exposure elevates corticosterone, promotes sperm Gnas‐ICR hypermethylation, and is associated with ovarian Gnas upregulation, cAMP/PKA/CREB–StAR activation, enhanced estradiol synthesis, and PPP‐like phenotypes ...
Jing Huang, Lu Chen, Tiancheng Wu, Yating Li, Hui Wang   +4 more
wiley   +1 more source

Adrenal-preserving surgery of adrenal tumours.

Endokrynologia Polska, 2015
Currently, laparoscopic adrenalectomy is seen as more than just the preferred method, in fact as a routine procedure, always bearing in mind, however, the developed restraints on its usage. The size of the tumour, recurrent disease, and the existing invasive process all remain factors which determine the indications for operation.
Otto, Maciej, Dzwonkowski, Jacek
openaire   +2 more sources

The effect of therapeutic glucocorticoids on the adrenal response in a randomized controlled trial in patients with rheumatoid arthritis [PDF]

, 2005
Objective To measure the effect of low-dose systemic glucocorticoid treatment on the adrenal response to adrenocorticotropic hormone (ACTH) in patients with rheumatoid arthritis (RA).
Wollheim, Frank, Roger Hällgren, Wollheim, Frank A, WOLLHEIM, F, Björck, Ewa, Björck, E, Hickey, Sarah H, Herman Mielants, Mielants, Herman, Mielants, H, John R. Kirwan, Persson, T, Persson, Tore, Hickey, SH, Wollheim, Frank,, Kirwan, JR, Ewa Björck, Hällgren, Roger,, Hällgren, R, Kirwan, John R, Frank A. Wollheim, Wollheim, FA, Tore Persson, Lund University., Sarah H. Hickey   +24 more
core   +1 more source