Results 91 to 100 of about 80,621 (311)

Interventional oncology in children: Where are we now?

open access: yesJournal of Medical Imaging and Radiation Oncology, EarlyView.
Abstract Paediatric Interventional Oncology (IO) lags behind adult IO due to a scarcity of specific outcome data. The suboptimal way to evolve this field is relying heavily on adult experiences. The distinct tumour types prevalent in children, such as extracranial germ cell tumours, sarcomas, and neuroblastoma, differ strongly from those found in ...
Premal Amrishkumar Patel   +1 more
wiley   +1 more source

Pharmacophore Modeling and in Silico/in Vitro Screening for Human Cytochrome P450 11B1 and Cytochrome P450 11B2 Inhibitors

open access: yesFrontiers in Chemistry, 2017
Cortisol synthase (CYP11B1) is the main enzyme for the endogenous synthesis of cortisol and its inhibition is a potential way for the treatment of diseases associated with increased cortisol levels, such as Cushing's syndrome, metabolic diseases, and ...
Muhammad Akram   +5 more
doaj   +1 more source

Indices of adrenal cortical activity in men exposed to cold [PDF]

open access: yes, 1951
Thesis (M.A.)--Boston UniversityEvidence of physiological acclimatization of man to cold is scanty and not clear-cut. Certainly no adaptations have been described comparable to the dramatic changes which occur when men are acclimatized to heat.
Bass, David E.
core   +1 more source

Grey matter volume correlates with virtual water maze task performance in boys with androgen excess [PDF]

open access: yes, 2011
Major questions remain about the specific role of testosterone in human spatial navigation. We tested 10 boys (mean age 11.65 years) with an extremely rare disorder of androgen excess (Familial Male Precocious Puberty, FMPP) and 40 healthy boys (mean age
Cornwell, BR   +7 more
core   +2 more sources

Childhood Maltreatment and Cognitive Functioning in Bipolar Disorder: A Systematic Review and Meta‐Analysis

open access: yesActa Psychiatrica Scandinavica, EarlyView.
ABSTRACT Aims Characterising the association between childhood maltreatment (CM) and cognitive functioning in bipolar disorder (BD) is crucial for improving the understanding of how early environmental risk factors impact the presentation of the disorder.
Natalia E. Fares‐Otero   +7 more
wiley   +1 more source

Anti-perilipin-1 autoantibodies in autoimmune Addison’s disease and related endocrine disorders

open access: yesAutoimmunity
Immune-mediated lipodystrophy syndromes are rare autoimmune disorders characterized by complete or partial destruction of adipocytes in the body. Recently, autoantibodies against perilipin-1 (PLIN1-autoAbs) have been linked to lipodystrophy.
Muhammad O. Rahman   +7 more
doaj   +1 more source

International Evidence‐Based Guidelines for Traditional Chinese Medicine Management of Allergic Rhinitis

open access: yesAllergy, EarlyView.
ABSTRACT Allergic rhinitis (AR) is a prevalent chronic condition that significantly impacts patients' quality of life and poses challenges to effective management. Traditional Chinese medicine (TCM) offers a holistic approach, emphasizing syndrome differentiation, individualized care, and natural treatment strategies.
Qin‐Wei Fu   +74 more
wiley   +1 more source

Systemic corticosteroids for acute otitis media in children [PDF]

open access: yes, 2018
Background: Acute otitis media (AOM) is a common acute infection in children. Pain is its most prominent and distressing symptom. Antibiotics are commonly prescribed for AOM, although they have only a modest effect in reducing pain at two to three days.
Beller, Elaine M   +6 more
core   +1 more source

Non‐canonical PKG1 regulation in cardiovascular health and disease

open access: yesBritish Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

Interrelations of the endocrine organs [PDF]

open access: yes, 1924
Thesis (M.A.)--Boston ...
Birrell, Ethel Jane
core   +1 more source

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