Results 71 to 80 of about 44,918 (249)

Salivary Cortisol Levels Representing Serum Cortisol Levels in Atopic Dermatitis Patients

Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology), 2017
Background: Atopic dermatitis (AD) is a chronic inflammatory skin disorder, recurrent lesion with a distinctive and specific distribution of lesions according phases.
Novia Indriyani Adisty, Marsudi Hutomo, Diah Mira Indramaya   +2 more
doaj   +1 more source

Synergistic Toxicity of Low‐Concentration Metal Mixture on Male Rats: Reproductive, Renal, and Hepatic Effects

Environmental Toxicology, EarlyView.
ABSTRACT Mining plays a crucial role in economic development, but improper management can lead to severe environmental degradation. Particularly for iron ore, mining generates vast amounts of tailings often stored in unstable dams. This study aims to investigate the toxicological impacts of environmentally relevant concentrations of metals mixture ...
Kalinka Helóra Gomes de Almeida, Thalita Tofanin Sargiani D'Assumpção, Ana Priscila Gomes Silva, Carolina Rocha Moreira de Oliveira, Tailisi Hoppe Trevizani, Rubens Cesar Lopes Figueira, Lucas Buruaem Moreira, Juliana Elaine Perobelli   +7 more
wiley   +1 more source

Anti-perilipin-1 autoantibodies in autoimmune Addison’s disease and related endocrine disorders

Autoimmunity
Immune-mediated lipodystrophy syndromes are rare autoimmune disorders characterized by complete or partial destruction of adipocytes in the body. Recently, autoantibodies against perilipin-1 (PLIN1-autoAbs) have been linked to lipodystrophy.
Muhammad O. Rahman, Andre Sulen, Lars Breivik, Silke Appel, Mark S. Anderson, Bergithe E. Oftedal, Anette S. B. Wolff, Eystein S. Husebye   +7 more
doaj   +1 more source

Sphingosine-1-phosphate lyase expression in embryonic and adult murine tissues

Journal of Lipid Research, 2012
Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid involved in immunity, inflammation, angiogenesis, and cancer. S1P lyase (SPL) is the essential enzyme responsible for S1P degradation. SPL augments apoptosis and is down-regulated in cancer.
Alexander D. Borowsky, Padmavathi Bandhuvula, Ashok Kumar, Yuko Yoshinaga, Mikhail Nefedov, Loren G. Fong, Meng Zhang, Brian Baridon, Lisa Dillard, Pieter de Jong, Stephen G. Young, David B. West, Julie D. Saba   +12 more
doaj   +1 more source

Functional urinary bladder paraganglioma in a child presenting with obstructive uropathy: A rare case report

UroPrecision, EarlyView.
Abstract Background Pediatric urinary bladder paraganglioma is an exceptionally rare neuroendocrine tumor arising from chromaffin cells within the detrusor muscle. Due to its rarity and variable presentation, early diagnosis can be challenging, often requiring a high index of clinical suspicion and multimodal evaluation.
Shameer Tahir, Eisha Sattar, Javeria Khan   +2 more
wiley   +1 more source

Pharmacophore Modeling and in Silico/in Vitro Screening for Human Cytochrome P450 11B1 and Cytochrome P450 11B2 Inhibitors

Frontiers in Chemistry, 2017
Cortisol synthase (CYP11B1) is the main enzyme for the endogenous synthesis of cortisol and its inhibition is a potential way for the treatment of diseases associated with increased cortisol levels, such as Cushing's syndrome, metabolic diseases, and ...
Muhammad Akram, Watcharee Waratchareeyakul, Joerg Haupenthal, Rolf W. Hartmann, Rolf W. Hartmann, Daniela Schuster   +5 more
doaj   +1 more source

Evaluation of thyroglobulin autoantibodies in dogs at the time of diagnosis of hypoadrenocorticism and during treatment

Veterinary Record, EarlyView.
Abstract Background Autoimmune thyroiditis (AIT) may occur more frequently in dogs with hypoadrenocorticism (HA) than previously recognised. The objective of this study was to determine the presence of thyroglobulin autoantibodies (TgAAs) in dogs with HA.
Christin Emming, Sina Strey, Ina Leiter, Reinhard Mischke, Holger Volk, Marion Schmicke, Johanna Rieder   +6 more
wiley   +1 more source

Coexistence of primary aldosteronism and micro-pheochromocytoma: a case report with pathological analysis and literature review

Frontiers in Medicine
BackgroundPrimary aldosteronism (PA) and pheochromocytoma (PHEO) are both causes of secondary hypertension. Since these two diseases have different pathogeneses, the coexistence of PA and PHEO is very rare and poses challenges in diagnosis and treatment ...
Bo Sun, Hanxiao Yu, Minzhi He, Zhe Wang, Yan Zhang, Ziyu Liu, Jiaming Wen, Xiaoxiao Song   +7 more
doaj   +1 more source

Effects of Obstructive Sleep Apnea on Personality and Temperament: A Cohort and Mendelian Randomization Study

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Obstructive sleep apnea (OSA) is associated with neurocognitive impairment, but its causal relationship with personality traits remains poorly understood. This study investigates the association and causality between OSA and personality using both cohort and genetic data.
Jian‐Hong Liao, Yun‐Han Shi, Xin‐Peng Xu, Yan‐Ru Li, De‐Min Han   +4 more
wiley   +1 more source

Interventional oncology in children: Where are we now?

Journal of Medical Imaging and Radiation Oncology, EarlyView.
Abstract Paediatric Interventional Oncology (IO) lags behind adult IO due to a scarcity of specific outcome data. The suboptimal way to evolve this field is relying heavily on adult experiences. The distinct tumour types prevalent in children, such as extracranial germ cell tumours, sarcomas, and neuroblastoma, differ strongly from those found in ...
Premal Amrishkumar Patel, Fernando Gómez Muñoz   +1 more
wiley   +1 more source