Results 141 to 150 of about 80,621 (311)
ACTH bioassay with isolated rat adrenal cells: ACTH activity of the porcins lipotropic peptide B [PDF]
, 1974 Baur, X. +5 more
core +1 more source
USSR space life sciences digest, issue 27 [PDF]
This is the twenty-fifth issue of NASA's Space Life Sciences Digest. It contains abstracts of 30 journal papers or book chapters published in Russian and of 2 Soviet monographs. Selected abstracts are illustrated with figures and tables from the original.
Frey, Mary Ann +4 more
core +2 more sources
Evaluation of preclinical antipsychotic models used to support first‐in‐human clinical trials
British Journal of Pharmacology, Volume 183, Issue 7, Page 1364-1389, April 2026.Abstract Schizophrenia is regarded as a complex and heterogeneous psychiatric disorder, characterised by diverse symptoms and comorbidities, which complicate both clinical management and drug development. Current pharmacological treatment, primarily based on dopamine D2 receptor antagonism or partial agonism, which has not markedly progressed since the
Thi Viet Ha Nguyen +2 more
wiley +1 more source
British Journal of Pharmacology, Volume 183, Issue 7, Page 1313-1340, April 2026.Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang +18 more
wiley +1 more source
Automated competitive protein binding analysis and radioimmunoassay of serum cortisol without prior organic solvent extraction [PDF]
, 1974 Braun, J. +2 more
core +1 more source
Homo sapiens, industrialisation and the environmental mismatch hypothesis
Biological Reviews, Volume 101, Issue 2, Page 580-601, April 2026.ABSTRACT For the vast majority of the evolutionary history of Homo sapiens, a range of natural environments defined the parameters within which selection shaped human biology. Although human‐induced alterations to the terrestrial biosphere have been evident for over 10,000 years, the pace and scale of change has accelerated dramatically since the onset
Daniel P. Longman, Colin N. Shaw
wiley +1 more source
Clinical Practice Patterns in Bone Health Assessment and Management in Endogenous Cushing's Syndrome
Clinical Endocrinology, Volume 104, Issue 4, Page 302-311, April 2026.ABSTRACT Objective Skeletal fragility is a common complication of endogenous Cushing's Syndrome (CS), although specific guidelines for managing bone health are lacking. This study aimed to assess clinicians' current engagement with bone health assessment and management in patients with endogenous CS. Design Retrospective‐cohort design. Patients Seventy‐
Preeshila Behary +10 more
wiley +1 more source
Addison's Disease Presenting with Hypercalcaemia, Acute Kidney Injury, and Anxiety. [PDF]
CureusTshering S, Qayyum W, Kapoor A.
europepmc +1 more source
Mitochondrial DNA Depletion Syndrome 1 (MTDPS1)—A Novel Cause of Premature Ovarian Insufficiency
Clinical Genetics, Volume 109, Issue 4, Page 784-787, April 2026.We describe a woman with MNGIE due to a novel homozygous TYMP nonsense variant and propose MNGIE as the cause of her premature ovarian insufficiency—a rarely reported association—highlighting the need to consider mitochondrial disease in unexplained POI, especially in atypical, consanguineous presentations. ABSTRACT Mitochondrial DNA depletion syndrome
Michael Matheou +3 more
wiley +1 more source