Results 21 to 30 of about 80,621 (311)

Eplerenone–A novel Mineralocorticoid receptor antagonist for the clinical application

Environmental Disease, 2022
Aldosterone is produced from the zona glomerulosa of the adrenal cortex in the adrenal gland, which is main mineralocorticoid hormone. Upon binding the mineralocorticoid receptor, it regulates sodium and potassium absorption, secretion, and retention ...
Nan-Nan Wu, Yuan-Yuan Zhang, Dong Zhao
doaj   +1 more source

Polyglandular Syndrome with Complications and a Rare Co-existence of Hypercortisolism in a Young Girl: An Internist Approach [PDF]

Journal of Clinical and Diagnostic Research, 2023
Patients diagnosed with Type 1 Diabetes Mellitus (T1DM) can sometimes manifest as part of broader clinical presentations known as Autoimmune Polyglandular Syndromes (APS).
K Vidhya, P Ananthkrishnan, Prasan Kumar Panda   +2 more
doaj   +1 more source

Label-free enrichment of adrenal cortical progenitor cells using inertial microfluidics. [PDF]

, 2012
Passive and label-free isolation of viable target cells based on intrinsic biophysical cellular properties would allow for cost savings in applications where molecular biomarkers are known as well as potentially enable the separation of cells with little-
Brinckerhoff, Tatiana Z, Di Carlo, Dino, Dunn, James CY, Hur, Soojung Claire, Walthers, Christopher M   +4 more
core   +2 more sources

Genome editing in the adrenal gland: a novel strategy for treating congenital adrenal hyperplasia [PDF]

Exploration of Endocrine and Metabolic Diseases
Congenital adrenal hyperplasia due to 21-hydroxylase deficiency leads to high morbidity and mortality, despite the availability of life-saving corticosteroid replacement therapy.
Eva B. van Dijk, Samantha L. Ginn, Ian E. Alexander, Lara E. Graves   +3 more
doaj   +1 more source

Adrenal Cytomegaly: Two Cases Detected by Prenatal Diagnosis

Asian Journal of Surgery, 2003
We report our experience with two cases of adrenal cytomegaly, both of which were detected as cystic adrenal masses during prenatal ultrasonographic examinations. In Case 1, a left suprarenal cystic mass was detected in the fetus at 25 weeks of gestation.
Shin-ichi Noguchi, Kouji Masumoto, Tomoaki Taguchi, Sachiyo Suita   +3 more
doaj   +1 more source

Management of congenital adrenal hyperplasia due to 21-hydroxylase deficiency in children and adolescents: review

Revista Médica de Minas Gerais, 2022
OBJECTIVE: To describe the diagnosis and clinical management of 21-hydroxylase deficiency (21OH-D), in the current context of including the disease in neonatal screening programs, as well as genetic, pathophysiological characteristics, and manifestations
Barra, Cristina Botelho, Silva, Ivani Novato   +1 more
doaj   +1 more source

An Autopsy Case With Fragile X-Associated Tremor/Ataxia Syndrome Presenting Intranuclear Inclusion Bodies Mainly in the Limbic System. [PDF]

Neuropathology
ABSTRACT Fragile X‐associated tremor/ataxia syndrome (FXTAS) is a neurodegenerative disorder characterized by a late onset and slow progression caused by a premutation (55–200 CGG repeat) in the fragile X mental retardation (FMR1) gene. Here, we report the case of a Japanese patient with FXTAS which is the first case autopsied in Japan. The patient was
Shioya A, Ishii K, Sato T, Noguchi M, Tamaoka A, Saito Y.   +5 more
europepmc   +2 more sources

Alternation of Resting-State Functional Connectivity Between Visual Cortex and Hypothalamus in Guinea Pigs With Experimental Glucocorticoid Enhanced Myopia After the Treatment of Electroacupuncture

Frontiers in Neuroinformatics, 2021
Excessive glucocorticoids (GC) may lead to the aggravation of several basic diseases including myopia, due to plasma hormone imbalances associated with the hypothalamic–pituitary–adrenal axis (HPAA).
Tao Zhang, Qian Jiang, Furu Xu, Ruixue Zhang, Dezheng Liu, Dadong Guo, Jianfeng Wu, Ying Wen, Xingrong Wang, Wenjun Jiang, Hongsheng Bi   +10 more
doaj   +1 more source

Effects of intrauterine exposure to synthetic glucocorticoids on fetal, newborn, and infant hypothalamic-pituitary-adrenal axis function in humans : a systematic review [PDF]

, 2009
BACKGROUND: Synthetic glucocorticoids are commonly used in reproductive medicine. Fetal organ systems are highly sensitive to changes in the intrauterine environment, including overexposure to glucocorticoids.
1994 Effect of corticosteroids for fetal maturation on perinatal outcomes, Alkalay, Anderson, Andrews, Arlt, Arnold, Asa, Ashwood, Audus, Baker, Ballabh, Ballard, Ballard, Bamberger, Banks, Banks, Barbazanges, Battin, Baulieu, Benassayag, Benediktsson, Bertram, Bettendorf, Blanford, Blettner, Blumenfeld, Bolt, Bolt, Bradley, Bresson, Brosnan, Brown, Burlet, Buske-Kirschbaum, Buske-Kirschbaum, Buske-Kirschbaum, Buske-Kirschbaum, Buttgereit, Carroll, Cattarelli, Charmandari, Christopher Pryce, Chrousos, Cintra, Clifton, Cole, Condon, Crowley, Crowley, Cummings, Czock, Dalziel, Davis, Davis, Dawes, De Kloet, De Kloet, de Kloet, De Kloet, de Kloet, de Weerth, Dean, Dean, Diederich, Diego, Dobbing, Doyle, Dörr, Dörr, Dwan, Easterbrook, Ebrecht, Felszeghy, Fiad, Ford, French, French, Fries, Gatelais, Gayrard, Gennser, Giannakoulopoulos, Giannakoulopoulos, Gibbs, Gitau, Gitau, Glover, Goland, Grier, Grossmann, Gunther Meinlschmidt, Gutteling, Haley, Hanna, Hauser, Haussmann, Heckmann, Heim, Herman, Hingre, Holsboer, Högger, Ioannidis, Jahnukainen, Jaquier, Jeffray, Jobe, Jüni, Kairalla, Kajantie, Kajantie, Kalabis, Kalabis, Kamphuis, Kanitz, Kapoor, Kapoor, Karemaker, Kari, Karlsson, Karssen, Kauppila, Kavelaars, Keene, Kirschbaum, Klemcke, Kononen, Korte, Krauer, Lee, Lee, Lee, Levine, Levitt, Liggins, Liggins, Lindh, Lindsay, Little, Loebstein, MacArthur, Macnaughton, Manabe, Marinoni, Marion Tegethoff, Mark, Mark, Matthews, McAlister, Meadow, Mears, Meijer, Melby, Mesiano, Miller, Modi, Moss, Muneoka, Murphy, Murphy, Murphy, Murphy, National Institutes of Health Consensus Development Panel, Nelson, Nelson, Ng, Ng, Ng, Ng, Ng, Ng, Ng, Noguchi, Nomura, Noorlander, Nordenström, Nykänen, O'Regan, O'Shea, Oelkers, Ohrlander, Ohrlander, Oken, Olufemi, Osathanondh, Owen, Ozawa, Pacheco, Paddock, Parker Jr, Parker Jr, Patel, Peets, Pepe, Pepe, Petersen, Petersen, Petraglia, Petropoulos, Phillips, Pryce, Pryce, Reichardt, Reis, Rizvi, Roberts, Rocci Jr, Rosati, Samtani, Sandesh Kiran, Sapolsky, Sánchez, Schatz, Schwab, Schwab, Seckl, Seckl, Seckl, Serón-Ferré, Shulman, Sippell, Sloboda, Speirs, Speiser, Stein, Streeten, Stroup, Sucheston, Sun, Sybulski, Szabó, Taylor, Tenhola, Teramo, Terrone, Terrone, Thliveris, Trestman, Tsigos, Uhr, Uno, van der Heide-Jalving, Van Hoof, van Runnard Heimel, van Runnard Heimel, Veldhuis, Veldhuis, Vogl, Walters, Watterberg, Welberg, White, Whittaker, Wilson, Wittekind, Yates, Yeh, Yeh   +257 more
core   +2 more sources

In vivo vesicular acetylcholine transporter density in human peripheral organs: an [18F]FEOBV PET/CT study

EJNMMI Research, 2022
Background The autonomic nervous system is frequently affected in some neurodegenerative diseases, including Parkinson’s disease and Dementia with Lewy bodies.
Jacob Horsager, Niels Okkels, Nathalie Van Den Berge, Jan Jacobsen, Anna Schact, Ole Lajord Munk, Kim Vang, Dirk Bender, David J. Brooks, Per Borghammer   +9 more
doaj   +1 more source