Results 31 to 40 of about 80,621 (311)

Genetic variation of TLR4 influences immunoendocrine stress response: an observational study in cardiac surgical patients [PDF]

open access: yes, 2011
Introduction: Systemic inflammation (e.g. following surgery) involves Toll-like receptor (TLR) signaling and leads to an endocrine stress response. This study aims to investigate a possible influence of TLR2 and TLR4 single nucleotide polymorphisms (SNPs)
Koch, Alexander   +9 more
core   +1 more source

Critical roles of endogenous glucocorticoids for disease tolerance in malaria

open access: yes, 2019
During malaria, the hypothalamic-pituitary-adrenal (HPA) axis is activated and glucocorticoid (GC) levels are increased, but their essential roles have been largely overlooked.
De Bosscher, Karolien   +4 more
core   +1 more source

Erosive pustular dermatosis of the scalp - is it really a rare condition? [PDF]

open access: yesVojnosanitetski Pregled, 2014
Introduction. Erosive pustular dermatosis of the scalp (EPDS) is a rare disorder of unknown etiology that usually occurs in the elderly and is characterized by multiple pustules, erosions and crusts that appear on the scalp leading to scarring ...
Levakov Olivera, Gajić Branislava
doaj   +1 more source

Measurement of the adrenal cortex reserve using depot beta 1-24-corticotrophin. II---in thyroid diseases.

open access: yesActa Médica Portuguesa, 1979
Mean plasma cortisol 4 to 6 hours after 1 mg Synacthen Depot in normal subjects, simple goiter and hypothyroidism were not significantly different. On the contrary after stimulation cortisol levels in untreated hyperthyroidism were significantly below ...
A. Galvão-Teles
doaj   +1 more source

Immunosuppressors and immunomodulators in Neurology - Part I: a guide for management of patients underimmunotherapy

open access: yesArquivos de Neuro-Psiquiatria, 2021
For patients with autoimmune diseases, the risks and benefits of immunosuppressive or immunomodulatory treatment are a matter of continual concern. Knowledge of the follow-up routine for each drug is crucial, in order to attain better outcomes and avoid ...
Fabiano Ferreira Abrantes   +10 more
doaj   +1 more source

Clonal Composition of Human Adrenocortical Neoplasms [PDF]

open access: yes, 1994
The mechanisms of tumorigenesis of adrenocortical neoplasms are still not understood. Tumor formation may be the result of spontaneous transformation of adrenocortical cells by somatic mutations.
Abdelhamid, S.   +7 more
core  

Altered Expression of the CB1 Cannabinoid Receptor in the Triple Transgenic Mouse Model of Alzheimer's Disease [PDF]

open access: yes, 2014
The endocannabinoid system has gained much attention as a new potential pharmacotherapeutic target in various neurodegenerative diseases, including Alzheimer's disease (AD).
*EQUAL CONTRIBUTION   +12 more
core   +1 more source

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

open access: yesAdvanced Science, EarlyView.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun   +7 more
wiley   +1 more source

Primary hyperaldosteronism in a patient with autonomous cortisol secretion and bilateral adrenal adenomas

open access: yesЛечащий Врач
Background. Formations of the adrenal cortex may have mixed secretion and produce aldosterone and cortisol. The number of clinical cases of combined secretion of aldosterone and cortisol (the so-called Conching syndrome) is increasing.
Z. R. Shafigullina   +6 more
doaj   +1 more source

Transrectal ultrasonography of the adrenal glands in donkeys (Equus asinus) [PDF]

open access: yes, 2016
Little information is available for medical imaging in donkeys and no report about adrenal glands ultrasonography can be found in scientific literature. The feasibility of transrectal ultrasonography of the adrenal glands was tested on 30 healthy donkeys
Cerquetella, Matteo   +6 more
core   +1 more source

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