Results 101 to 110 of about 650,508 (231)

Annual Research Review: What processes are dysregulated among emotionally dysregulated youth? – a systematic review

Journal of Child Psychology and Psychiatry, Volume 66, Issue 4, Page 516-546, April 2025.
Proliferation of the term “emotion dysregulation” in child psychopathology parallels the growing interest in processes that influence negative emotional reactivity. While it commonly refers to a clinical phenotype where intense anger leads to behavioral dyscontrol, the term implies etiology because anything that is dysregulated requires an impaired ...
Joseph C. Blader, Amy S. Garrett, Steven R. Pliszka   +2 more
wiley   +1 more source

Annual Research Review: Sex differences in conduct disorder – revisiting existing evidence and exploring future directions

Journal of Child Psychology and Psychiatry, EarlyView.
Conduct disorder (CD) is a common psychiatric disorder in youth, characterized by severe and recurrent aggressive and antisocial behaviors and associated with substantial healthcare and societal costs. Rates of CD increase during adolescence in both sexes, with the male‐to‐female ratio narrowing to approximately 1:1.
Anka Bernhard, Christine M. Freitag, Kerstin Konrad, Lucres Jansen, Andreas G. Chiocchetti, Christina Stadler, Stephane A. De Brito, Graeme Fairchild, Gregor Kohls   +8 more
wiley   +1 more source

Annual Research Review: A probe into sensitive periods – how the developmental timing of adverse childhood experiences influences brain structure and function – a systematic review

Journal of Child Psychology and Psychiatry, EarlyView.
It is proposed that adverse childhood experiences (ACEs) – potent predictors of mental illness – exert time‐dependent effects on neurodevelopment, reflecting periods of heightened neuroplasticity and developmental sensitivity. We systematically reviewed neuroimaging studies examining the role of timing in the association of ACE exposure with brain ...
Stephanie Hartanto, Divyangana Rakesh, Catherine Orr, Ebony Forlano, Muskan Khetan, Sarah Whittle   +5 more
wiley   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger, Yuxi Zhou, Jiawen Yong, Lei Wang, Sabine Ruf, Joerg Meyle   +5 more
wiley   +1 more source

THE 17-HYDROXYPROGESTERONE LEVEL, ANDROSTENEDIONE LEVEL, AND SIDE EFFECTPOST HYDROCORTISONE THERAPY OF CONGENITAL ADRENAL HYPERPLASIA PATIENTS [PDF]

, 2010
Background: Congenital Adrenal Hyperplasia (CAH) is the most common 46,XX DSDs, which occurred when one of the enzymes required for cortisol and aldosterone synthesis in adrenal gland is deficit, therefore performed adrenal hormone imbalance.
Pratami, R. Rizcky Erika
core   +1 more source

Steroidal antiinflammatory drugs: glucocorticoids [PDF]

Einstein (São Paulo), 2008
Glucocorticoids are largely used drugs because of theirimmunosuppressive and anti-infl ammatory effects in the treatment ofmany rheumatic and other infl ammatory diseases. However, their useis sometimes limited by numerous adverse reactions.
Sônia Maria Alvarenga Anti, Rina Dalva Neubarth Giorgi, Wiliam Habib Chahade   +2 more
doaj  

Motor Sequence Learning Under Sleep Deprivation

Journal of Sleep Research, EarlyView.
ABSTRACT Sleep deprivation (SD) compromises declarative memory encoding and subsequent consolidation, yet its consequences for the acquisition of new motor skill learning remain unknown. Forty‐eight healthy adults underwent either one night of total SD or normal sleep and were tested the next morning using a multimodal approach combining psychomotor ...
Guillaume Digonet, Thomas Lapole, Juliette Gélébart, Jérémie Bouvier, Mélanie Prudent, Vincent Pialoux, Maxime Pingon, Emeric Stauffer, Ursula Debarnot   +8 more
wiley   +1 more source

Microbiome and Metabolomics in Obesity: Advances in Understanding and Interventions Across the Lifespan

Obesity Reviews, EarlyView.
ABSTRACT Obesity arises from intertwined and reciprocal diet‐microbiome‐host pathways that reshape energy balance, insulin sensitivity, and inflammation. This review synthesizes mechanistic links between microbial functions and metabolic control, charts lifestyle‐related lifecourse dynamics from birth to older age, examines how GLP‐1‐based therapies ...
Ioanna Panagiota Kalafati, David Krongauz, Alice Bosco, Antonio Noto, Cristina Piras, Maria Kafyra, Angelica Dessì, Matteo Mauri, Luigi Atzori, Adina Weinberger, Vassilios Fanos, George V. Dedoussis, on behalf of the BETTER4U consortium   +12 more
wiley   +1 more source

Changes in morphology and function of adrenal cortex in mice fed a high-fat diet

, 2014
Background/objectives: Obesity is a major risk factor for the development of type 2 diabetes and other debilitating diseases. Obesity and diabetes are intimately linked with altered levels of adrenal steroids.
Bornstein, S. R., Chavakis, T., Eisenhofer, G., Eaton, S., Swierczynska, M. M., Mateska, I., Lamounier-Zepter, V., Peitzsch, M.   +7 more
core   +1 more source

Understanding Exosomes in Hair Regeneration

Periodontology 2000, EarlyView.
Abstract Background Alopecia is a prevalent condition correlated with significant psychosocial challenges, while contemporary treatments exhibit variable efficacy, require extended use, and may cause adverse effects. This review aimed to comprehensively assess exosome‐mediated interventions as a novel cell‐free regenerative approach for hair ...
Paras Ahmad, Catherine Davies, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source