Results 91 to 100 of about 36,155 (274)

Corticoids: 60 Years Later a Pending Subject [PDF]

open access: yesRevista Ciencias de la Salud, 2007
The objective of this article is to make a brief compilation of the physiology of the hypothalamic-pituitary-adrenal axis in order to understandthe role of the exogenous corticoids as therapeutic tools in innumerable pathologies, but when used ...
Silvia Gómez Ordóñez   +2 more
doaj  

Renal‐vascular axis: unmasking its role in vascular endothelial growth factor‐inhibitor vascular toxicity in cancer patients

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley   +1 more source

Pharmacological effects of triamcinolone associated with surgical glue on cutaneous wound healing in rats [PDF]

open access: yesActa Cirúrgica Brasileira
Purpose: The surgical glue is widely used in closing cutaneous surgical wounds. Corticosteroids are indicated for their anti-inflammatory and immunomodulatory properties.
Rosana Soares Araújo Doci   +9 more
doaj   +1 more source

Cancer pain: current practice and emerging targets

open access: yesBritish Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye   +5 more
wiley   +1 more source

Pharmacological treatment with a GABA(A) receptor modulator and a selective serotonin reuptake inhibitor as a mitigation strategy against aircraft noise‐induced cardiovascular and neuronal damage

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Noise pollution, particularly by aircraft, is a significant risk factor for cardiovascular disease. Aircraft noise activates stress response pathways in the brain, via the amygdala, the sympathetic nervous system and the hypothalamic–pituitary–adrenal axis.
Ivana Kuntić   +25 more
wiley   +1 more source

The effect of adrenal cortical hormones on electrolyte excretion.

open access: yes, 1962
The importance of tile adrenal cortex in influencing sodium and potassium metabolism is well established. The adrenal cortex secretes a number of steroid hormones which affect sodium and potassium excretion to varying degrees.
Uete, Tetsuo.
core  

The effects of acute heat stress on proliferative and apoptotic processes in the rat adrenal cortex

open access: yes, 2013
Hyperthermia can cause significant structural and functional reorganization of tissues and organs. The proliferative and apoptotic processes of rat adrenal cortex were analyzed by light and electron microscopy after an acute exposure to high ambient ...
Ajdžanović, V.   +9 more
core   +1 more source

Atrial natriuretic peptide counteracts aldosterone secretion by preventing acute angiotensin II‐induced cAMP signalling

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Aldosterone plays a key role in blood pressure and volume regulation. Enhanced aldosterone secretion contributes to cardiovascular and renal diseases. Therefore, inhibitors of aldosterone receptors and synthase are essential drugs for the treatment of hypertension and heart failure.
Sanika Mohagaonkar   +6 more
wiley   +1 more source

Differential Expression of a Stress-modulating Gene, BRE, in the Adrenal Gland, in Adrenal Neoplasia, and in Abnormal Adrenal Tissues

open access: yes, 2001
Genes that modulate the action of hormones and cytokines play a critical role in stress response, survival, and in growth and differentiation of cells.
Ying-bin Wang   +7 more
core   +2 more sources

Formation of Hormones In Vitro by Adrenal Preparations.

open access: yes, 1955
Saffran, Grad and Bayliss (1952) were the first to demonstrate the stimulation by ACTH of the production of adrenocortical hormones by the rat adrenal cortex in vitro.
Schonbaum, Eduard.
core  

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