Results 71 to 80 of about 68,013 (282)

Bile acid metabolism and sleep: Mechanistic interplay and clinical implications of the gut–liver–brain axis

open access: yesSleep Research, EarlyView.
Abstract The bidirectional interplay between sleep and metabolic homeostasis is fundamental to physiological health. While the roles of glucose and lipid metabolism in sleep regulation have been extensively characterized, bile acids (BAs), which are traditionally viewed as digestive surfactants, are emerging as critical metabolic messengers with ...
Yu Jiang   +4 more
wiley   +1 more source

Medical Treatment of Alcoholic Liver Disease

open access: yesThe Korean Journal of Gastroenterology, 2020
Alcoholic liver disease is a major cause of liver disease that results in significant morbidity and mortality in Korea. Abstinence is the most important strategy to prevent disease progression.
Do Seon Song
doaj   +1 more source

Neurophysiological responses to stressful motion and anti-motion sickness drugs as mediated by the limbic system [PDF]

open access: yes
Performance is characterized in terms of attention and memory, categorizing extrinsic mechanism mediated by ACTH, norepinephrine and dopamine, and intrinsic mechanisms as cholinergic.
Kohl, R. L., Odell, S.
core   +1 more source

Circadian rhythms and hormonal homeostasis: Pathophysiological implications [PDF]

open access: yes, 2017
Over recent years, a deeper comprehension of the molecular mechanisms that control biological clocks and circadian rhythms has been achieved. In fact, many studies have contributed to unravelling the importance of the molecular clock for the regulation ...
Bruscalupi, Giovannella, Gnocchi, Davide
core   +2 more sources

Research on sleep quality and influencing factors among medical staff in a tertiary hospital in Anhui Province, China

open access: yesSleep Research, EarlyView.
To assess sleep quality and identify key influencing factors among medical staff in a tertiary hospital to support health policy development. Conducted in July 2024 using validated scales: Pittsburgh Sleep Quality Index (PSQI); Depression, Anxiety, and Stress Scale‐21; and Assessed: sleep quality, latency, disturbances, and daytime dysfunction.
Xiao‐Ying Jin   +6 more
wiley   +1 more source

Indices of adrenal cortical activity in men exposed to cold [PDF]

open access: yes, 1951
Thesis (M.A.)--Boston UniversityEvidence of physiological acclimatization of man to cold is scanty and not clear-cut. Certainly no adaptations have been described comparable to the dramatic changes which occur when men are acclimatized to heat.
Bass, David E.
core   +1 more source

Grey matter volume correlates with virtual water maze task performance in boys with androgen excess [PDF]

open access: yes, 2011
Major questions remain about the specific role of testosterone in human spatial navigation. We tested 10 boys (mean age 11.65 years) with an extremely rare disorder of androgen excess (Familial Male Precocious Puberty, FMPP) and 40 healthy boys (mean age
Cornwell, BR   +7 more
core   +2 more sources

Synergistic Toxicity of Low‐Concentration Metal Mixture on Male Rats: Reproductive, Renal, and Hepatic Effects

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Mining plays a crucial role in economic development, but improper management can lead to severe environmental degradation. Particularly for iron ore, mining generates vast amounts of tailings often stored in unstable dams. This study aims to investigate the toxicological impacts of environmentally relevant concentrations of metals mixture ...
Kalinka Helóra Gomes de Almeida   +7 more
wiley   +1 more source

Evaluation of thyroglobulin autoantibodies in dogs at the time of diagnosis of hypoadrenocorticism and during treatment

open access: yesVeterinary Record, EarlyView.
Abstract Background Autoimmune thyroiditis (AIT) may occur more frequently in dogs with hypoadrenocorticism (HA) than previously recognised. The objective of this study was to determine the presence of thyroglobulin autoantibodies (TgAAs) in dogs with HA.
Christin Emming   +6 more
wiley   +1 more source

Identification of genetically predicted protein biomarkers and drug targets for prostate cancer via Mendelian randomization

open access: yesVIEW, EarlyView.
Prostate cancer, a leading cause of cancer in men globally, urgently requires improved diagnostic and treatment strategies. This study analyzed large genetic datasets and identified five key proteins (THBD, DST, IFI27L2, OSBPL10, PPP1R14A) that either increase or decrease cancer risk, while also exploring their roles in immune response and potential ...
Maoping Cai   +11 more
wiley   +1 more source

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