Results 71 to 80 of about 35,402 (224)

Conflict Social Networks of Critically Endangered Alpine Musk Deer in Captivity and Relationships With Fecal Steroid Hormones 圈养极危物种马麝的冲突社交网络及其与粪便类固醇激素的关联

Wildlife Letters, EarlyView.
We conducted a grouping study on 52 adult musk deer to investigate whether group sex composition modulates aggressive behavior and stress response in captive musk deer. We found that the conflict interactions of all‐male groups were significantly more than those of mixed groups, and compared with the mixed groups, the conflict interactions of all‐male ...
Xiaolong Wang, Jingqi Yang, Xiaoping Lu, Hong Ye, Wei Huang, Xiuxiang Meng   +5 more
wiley   +1 more source

Effect of Social Rank on Gut Microbes and Their Metabolites of Greater Long‐Tailed Hamsters (Tscherskia triton)

Integrative Zoology, EarlyView.
Social rank in greater long‐tailed hamsters (Tscherskia triton) shapes gut microbiota composition and metabolite profiles. Dominant males exhibit a “high‐vigilance, metabolically activated” phenotype, with elevated aggression and specific gut microbiota enriched in energy‐harvesting taxa and fecal queuine.
Da Zhang, Xiaoming Xu, Zhibin Zhang
wiley   +1 more source

Renal‐vascular axis: unmasking its role in vascular endothelial growth factor‐inhibitor vascular toxicity in cancer patients

British Journal of Pharmacology, EarlyView.
Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley   +1 more source

Effect of Naloxone Pretreatment on Rat suprarenal gland after Hepatic Ischemia–Reperfusion injury

Minia Journal of Medical Research
Introduction: The adrenal gland is a vital endocrine organ responsible for secreting adrenal hormones. One clinically significant condition is hepatic ischemia–reperfusion (IR) injury, which can lead to dysfunction in multiple distant organs. Naloxone is
Abdel Hamid AboBakr, samah mahmoud, Nashwa El-Tahawy, Rania Nour ElDeen, Medhat Ata   +4 more
doaj   +1 more source

Corticoids: 60 Years Later a Pending Subject [PDF]

Revista Ciencias de la Salud, 2007
The objective of this article is to make a brief compilation of the physiology of the hypothalamic-pituitary-adrenal axis in order to understandthe role of the exogenous corticoids as therapeutic tools in innumerable pathologies, but when used ...
Silvia Gómez Ordóñez, Ángela María Gutiérrez Álvarez, Etna L. Valenzuela Plata en Salud, Team Physician CNS-Pain Unit Business Pfizer Colombia.   +2 more
doaj  

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Pharmacological effects of triamcinolone associated with surgical glue on cutaneous wound healing in rats [PDF]

Acta Cirúrgica Brasileira
Purpose: The surgical glue is widely used in closing cutaneous surgical wounds. Corticosteroids are indicated for their anti-inflammatory and immunomodulatory properties.
Rosana Soares Araújo Doci, Filipe Feitosa de Carvalho, Rodrigo César Gomes, Reinaldo José Gianini, Camilla Fanelli, Irene de Lourdes Noronha, Nelson Brancaccio dos Santos, Moema de Alencar Hausen, Daniel Komatsu, Priscila Randazzo-Moura   +9 more
doaj   +1 more source

Atrial natriuretic peptide counteracts aldosterone secretion by preventing acute angiotensin II‐induced cAMP signalling

British Journal of Pharmacology, EarlyView.
Background and Purpose Aldosterone plays a key role in blood pressure and volume regulation. Enhanced aldosterone secretion contributes to cardiovascular and renal diseases. Therefore, inhibitors of aldosterone receptors and synthase are essential drugs for the treatment of hypertension and heart failure.
Sanika Mohagaonkar, Egor B. Skryabin, Bettina M. Buchholz, Michaela Kuhn, Celso E. Gomez‐Sanchez, Stepan Gambaryan, Viacheslav O. Nikolaev   +6 more
wiley   +1 more source

Gut microbiota as a novel therapeutic target for eating disorders and obesity

British Journal of Pharmacology, EarlyView.
The graphical abstract highlights the bidirectional interaction between the gut microbiota and central homeostatic and hedonic mechanisms regulating food intake, which contributes to overweight and obesity. It also illustrates emerging microbiota‐based biomarkers and therapeutic strategies (including prebiotics, probiotics, postbiotics, synbiotics and ...
Solveiga Samulėnaitė, Victor Mathis, Emmanuel Darcq, Aurelijus Burokas, Elena Martín‐García, Rafael Maldonado   +5 more
wiley   +1 more source

Glucocorticoids and HPA axis regulation in the stress–obesity connection: A comprehensive overview of biological, physiological and behavioural dimensions

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton, Myrte Schoenmakers, Brenda W. J. H. Penninx, Mariëtte R. Boon, Elisabeth F. C. van Rossum   +4 more
wiley   +1 more source