Results 141 to 150 of about 36,155 (274)

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

Advanced Science, Volume 13, Issue 32, 9 June 2026.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun, Changying Jing, Martina Tetti, Siyuan Gong, Jia Wei, Yingxian Pang, Martin Reincke, Tracy Ann Williams   +7 more
wiley   +1 more source

Comprehensive Quantitative Urinary Steroid Profiling of 29 Steroids Using Liquid Chromatography‐Tandem Mass Spectrometry

Analytical Science Advances, Volume 7, Issue 1, June 2026.
ABSTRACT Steroids are critical for numerous physiological processes; disruption in their metabolism is associated with numerous endocrine disorders. Steroid quantification is essential to improve the understanding and diagnosis of these pathologies. Historically, urinary steroid profiling has been performed using low‐throughput gas chromatography mass ...
Joshua T. Bain, Fozia Shaheen, Alessandro Prete, Lorna C. Gilligan, Angela E. Taylor   +4 more
wiley   +1 more source

Sleep Traits and Cognitive Function: A Prospective Cohort Study With Exploration of Inflammatory Biomarkers

Brain and Behavior, Volume 16, Issue 6, June 2026.
ABSTRACT Introduction Although sleep disturbance is closely linked to cognitive impairment, the specific sleep‐related characteristics driving this deficit remain undetermined, with the mechanistic contribution of biomarkers also poorly characterized.
Chi Peng, Fan Yang, Fanfan Li, Ronghui Zhu, Lei Li, Zhentao Zhang, Jianyao You, Rui Wang, Yingyi Qin, Shuogui Xu   +9 more
wiley   +1 more source

Neurocognitive Aging Following Acute Illness: Pathobiology and a Framework for Developing Neurotherapeutic Agents

Brain and Behavior, Volume 16, Issue 6, June 2026.
In this review, we discuss the scientific basis for how neurocognitive aging occurs after critical illness, including sepsis, trauma, and burns, and the clinical need to develop therapies to reduce inflammation, protect the blood–brain barrier, remove senescent cells, and enhance neuroplasticity.
Errin Lawrence, Daniel Fulton, Poppy Brown, Subashini Suresh, Mark Morris, Paraskevi Goggolidou, Sree Chaithanya, Marcus Abbawy, Amelia Wild, Prashant Nasa, Niharika A. Duggal, Fang Gao‐Smith, Zubair Ahmed, Suresh Renukappa, Tonny Veenith   +14 more
wiley   +1 more source

Problems in the use of chemical and functional nomenclatures for steroids in human physiology, biology and pharmacology. [PDF]

RSC Adv
Honour JW.
europepmc   +1 more source

Bibliometric Analysis of Cubebenes and Related Sesquiterpenes: Natural Occurrence, Biosynthesis, Pharmacological Activities, and In‐Silico‐Based Future Therapeutic Potential

eFood, Volume 7, Issue 3, June 2026.
Cubebene‐related sesquiterpenes, found across diverse biological sources, exhibit promising pharmacological activities, including anti‐inflammatory, neuroprotective, and anticancer effects. This review highlights their molecular diversity, ADME profiles, and predicted multitarget interactions, underscoring their therapeutic relevance and potential in ...
Khadija Boualam, Ahmet B. Ortaakarsu, Sohaib Khatib, Mohamed A. Farag, Mansour Sobeh   +4 more
wiley   +1 more source

Central Adrenal Insufficiency Developing After Right Partial Nephrectomy Involving Ectopic Adrenocortical Adenoma Mimicking Right Renal Carcinoma and a Retrospective Diagnosis of Adrenal Cushing's Syndrome: A Case Report. [PDF]

IJU Case Rep
Arinami K, Kikuchi S, Ohara N, Takizawa Y, Ikeda Y, Ito K, Hasegawa G, Hara N, Nishiyama T.   +8 more
europepmc   +1 more source

KREO Prevents CUMS‐Induced Depressive‐Like Behavior via Modulation of the BDNF Signaling Pathway

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
This study showed that Chinese Kushui Rose Essential Oil (KREO) can alleviate depressive symptoms, increase voluntary activity, and enhance exploratory behavior in mice induced with chronic unpredictable mild stress (CUMS) by elevating serotonin (5‐HT) levels and reducing hyperactivity of the hypothalamic–pituitary–adrenal (HPA) axis.
Yanni Wang, Zhaorong Yue, Manjie Xu, Wenjun Xu, Weizhong Zhang, Xiaolong Li, Qinghong Liu, Kailong Guan, Zewen Zhang, Yang Li, Xin Wang, Hongyu Li   +11 more
wiley   +1 more source

Excess female adrenal androgen secretion is a consequence of in utero androgenic excess in sheep. [PDF]

Reprod Fertil
Ramaswamy S, Siemienowicz K, McNeilly AS, Duncan WC, Rae MT.   +4 more
europepmc   +1 more source

Associations between anxiety, somatic pain and sleep disturbances in major depressive disorder and chronic pain: A cross‐sectional study with gender‐specific insights

General Psychiatry, Volume 39, Issue 3, June 2026.
ABSTRACT Background Major depressive disorder (MDD) and chronic pain (CP) demonstrate marked sex disparities, with higher prevalence and severity in females. However, the underlying mechanisms remain poorly understood. Aims We aimed to examine the intricate interplay among anxiety, physical pain and sleep disruptions in inpatients with depression and ...
Cuizhen Zhu, Jian Cheng, He Chen, Junwei Yan, Chao Li, Xiaoming Kong, Jiayi Hu, Jianliang Gao, Loufeng Zhang, Peijun Ju, Qingrong Xia   +10 more
wiley   +1 more source