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HORMONES OF THE ADRENAL CORTEX
Endocrinology, 1942THE ESSENTIAL CONTRIBUTION which subsequently led to the elucidation of the I chemical nature of the hormones of the adrenal cortex was the use of organic solvents for the extraction of the active material from epinephrine and toxic substances which are associated with the hormones in the gland (i, a).
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The Hormones of the Adrenal Cortex
1943Publisher Summary This chapter deals with work on the chemistry of the steroids of the adrenal cortex and of closely related compounds, which appeared during 1937–1942. On account of the war, work from some countries can be included only up to late 1941.
C. W. Shoppee, T. Reichstein
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Aldosterone: The minority hormone of the adrenal cortex
Steroids, 1995In comparison with the glucocorticoids cortisol and corticosterone, the mineralocorticoid aldosterone is a minority hormone of the mammalian adrenal cortex, and its proper function is dependent upon protective physiological mechanisms. These include a particular site of aldosterone synthesis in zona glomerulosa cells as well as a complex multifactorial
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HORMONE-SECRETING TUMORS OF THE ADRENAL CORTEX IN CHILDREN
Pediatrics, 1966In 12 children with hyperadrenocorticism caused by tumor of the adrenal cortex the most common clinical picture was that of a mixture of adrenogenital and Cushing's syndromes. All tumors were surgically removed; adrenal steroids were used in the preparation of 11 patients for operation.
A B, Hayles+4 more
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Sex hormone secretion by the adrenal cortex
1962The production of sex hormones by congenital hyperplasias or malignancies of the adrenal cortex has long been recognized as suggestive of a biochemical relationship between the adrenal cortex and the gonads. The embryological origin of these tissues from adjacent portions of the dorsal mesentery provided a plausible background for similarities (Poll ...
Evelyn Howard, Claude J. Migeon
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Adrenal cortex response to adrenocorticotropic hormone in dairy cattle
Domestic Animal Endocrinology, 1994Adult dairy cows were treated with a range of doses (0.0125mg to 0.4mg) of synthetic ACTH1-24 and the plasma cortisol response was measured. Peak response was independent of dose. Higher doses of ACTH had a more prolonged effect such that the integrated response was dose dependent. Dose response curves were examined by regression analyses.
K.L. Macmillan+2 more
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The effect of microwaves on the hormonal activity of the adrenal cortex
Bulletin of Experimental Biology and Medicine, 1962The histochemical method (silver impregnation according to Giroud and Leblond for ascorbic acid. sudan staining of lipoids) and polarization microscopy were used for studying the effect of a single exposure to microwave radiation on the hormonal activity of the adrenal cortex.
F. L. Leites, L. A. Skurikhina
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[68] Isolation of adrenal cortex cells—Hormone responses
1974Publisher Summary Suspensions of cells, freshly isolated from the organism, offer a number of advantages for the study of hormone action. They can be prepared within a few hours by methods that demand attention to detail but present no great technical difficulties.
Kevin Cummins+3 more
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Regulation by ACTH of steroid hormone biosynthesis in the adrenal cortex
Canadian Journal of Biochemistry and Cell Biology, 1983In this article, current knowledge about the mechanism of action of ACTH will be reviewed. Emphasis will be placed on events which occur subsequent to binding of ACTH to its receptor, stimulation of adenylate cyclase, and activation of protein kinase. In the first part of the review, the acute action of ACTH will be discussed with emphasis on present ...
Evan R. Simpson, Michael R. Waterman
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Effect of Chlorphentermine on Hormone Content and Function of the Adrenal Cortex in Rats [PDF]
Amphiphilic drugs like chlorphentermine induce a generalized lipid storage disease upon chronic application. The adrenal cortex is among the organs most heavily affected. We therefore determined the urinary corticosterone excretion during the treatment of rats with chlorphentermine and the corticosterone content of the adrenals and its blood level at ...
F Hartmann, F Jentzen
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