Results 221 to 230 of about 69,640 (339)

GWAS Identifies SNPs Associated With Severe Adverse Events and Efficacy in Advanced Renal Cell Carcinoma Treated With Nivolumab

open access: yesCancer Science, Volume 116, Issue 12, Page 3300-3308, December 2025.
This study highlights the importance of germline genetic markers in predicting severe trAEs caused by nivolumab. Our findings support their potential to guide personalized immunotherapy and improve treatment safety and efficacy in advanced ccRCC and other cancers.
Tokiyoshi Tanegashima   +26 more
wiley   +1 more source

Endocrine dysfunctions as complications and comorbidities of juvenile idiopathic arthritis. [PDF]

open access: yesReumatologia
Kamińska M   +5 more
europepmc   +1 more source

Alterations in Neuroinflammation, Microglia and Neuroplasticity in the Rat Hippocampus in a Combined Model of Periodontitis and Depression

open access: yesCNS Neuroscience &Therapeutics, Volume 31, Issue 12, December 2025.
Cascade of effects within the HP of rats exposed to a combined model of periodontitis and depression. Akt, Protein kinase B; BDNF, Brain‐derived neurotrophic factor; CA1, cornu ammonis 1; CA3, cornu ammonis 3; DG, dentate gyrus; iNOS, Inducible nitric oxide synthase; LPS, lipopolysaccharide; mTOR, Mammalian target of rapamycin; NFκB, Nuclear factor ...
Javier Robledo‐Montaña   +12 more
wiley   +1 more source

New Concepts of Regeneration and Renewal of Adrenal Chromaffin Cells. [PDF]

open access: yesInt J Mol Sci
Yaglova NV   +9 more
europepmc   +1 more source

Cellular mechanisms of long‐term osmoregulation in magnocellular neurons

open access: yesJournal of Neuroendocrinology, Volume 37, Issue 12, December 2025.
Abstract Osmoregulation is an essential homeostatic process that maintains the osmolality of the extracellular fluid (ECF) close to a physiological setpoint. Vasopressin (VP) plays a key role in osmoregulation and is secreted by the magnocellular neurosecretory cells (MNCs) of the hypothalamus.
Kirk D. Haan, Thomas E. Fisher
wiley   +1 more source

Multiple Organ Phenotype of Fatigue. [PDF]

open access: yesBiomolecules
Liu X, Zhao Z, Zhang Y, Zou J, Zhang L.
europepmc   +1 more source

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