Results 71 to 80 of about 131,760 (358)

Maternal gut microbiota‐derived daidzein prevents osteoporosis in female offspring following prenatal prednisone exposure

open access: yesiMeta, EarlyView.
Prenatal prednisone therapy (PPT)/prenatal prednisone exposure (PPE) induces long bone dysplasia, reduced peak bone mass (PBM), and increased osteoporosis susceptibility in female offspring. Maternal gut microbiota metabolite daidzein (DAI) mediates PPE‐induced osteoporosis susceptibility in female adult offspring.
Chi Ma   +13 more
wiley   +1 more source

Perinatal Exposure to the Neonicotinoid Thiacloprid Impacts Transcription of Neuroplasticity and Neuroendocrine Markers in Mice but Not in the Zebrafish Model

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Neonicotinoids are widely used insecticides in agriculture, aquaculture, pet care, and urban pest control. Initially developed to selectively target the insect cholinergic system, their extensive use has raised concerns about adverse effects on nontarget vertebrates.
Kirthana Kunikullaya U   +6 more
wiley   +1 more source

The role of hormones of the adrenal cortex in regulation of the muscular activity of a growing organism

open access: yesУчёные записки Казанского университета: Серия Естественные науки, 2018
We studied the endocrine mechanisms of urgent and long-term adaptation of children to increased physical stresses and, in particular, the role of hormones of the adrenal cortex in the regulation of the muscular activity of male athletes aged 11–15 years ...
M.V. Shaykhelislamova   +4 more
doaj  

Chronic adrenal insufficiency in children and adolescents

open access: yesЛечащий Врач, 2021
The review articles analyses modern data on etiology, pathogenesis, clinical picture in chronic adrenal insufficiency (CAI) in children and adolescents.It is indicated that, depending on the level of affection of hypothalamo-pituitary-adrenal axis ...
V. V. Smirnov, L. I. Bikbaeva
doaj  

A connection between extracellular matrix and hormonal signals during the development of the human fetal adrenal gland

open access: yesBrazilian Journal of Medical and Biological Research, 2005
The human adrenal cortex, involved in adaptive responses to stress, body homeostasis and secondary sexual characters, emerges from a tightly regulated development of a zone-specific secretion pattern during fetal life.
E. Chamoux, M. Otis, N. Gallo-Payet
doaj   +1 more source

Cell Apoptosis and Glucocorticoid‐Induced Osteonecrosis

open access: yesMed Research, EarlyView.
The review identifies glucocorticoid‐induced osteocyte/osteoblast apoptosis as central to femoral head osteonecrosis (GION), mediated through STAT1‐caspase‐3, PI3K/Akt, Wnt/β‐catenin, and oxidative stress pathways. Emerging therapies targeting these pathways (e.g., HIF‐1α stabilization, AMPK activation, and exosome‐mediated miRNA delivery) show ...
Xiumei Tang   +7 more
wiley   +1 more source

Role of astrocyte in neuroinflammation‐induced loss in neuroplasticity and subsequent onset of depression: A systematic review

open access: yesNeuroprotection, EarlyView.
Mechanistic crosstalk between microglia and astrocytes in major depressive disorder. Abstract Major depressive disorder (MDD) is a complex psychiatric condition increasingly linked to chronic neuroinflammation, particularly in the context of aging, stress, and systemic comorbidities.
Gaurav Singhal   +2 more
wiley   +1 more source

Are physiological oscillations physiological?

open access: yesThe Journal of Physiology, EarlyView., 2023
Abstract figure legend Mechanisms and functions of physiological oscillations. Abstract Despite widespread and striking examples of physiological oscillations, their functional role is often unclear. Even glycolysis, the paradigm example of oscillatory biochemistry, has seen questions about its oscillatory function.
Lingyun (Ivy) Xiong, Alan Garfinkel
wiley   +1 more source

Adrenal oncocytoma

open access: yesRevista Cubana de Medicina Militar, 2021
Introduction: Adrenal oncocytoma is a rare and incidental tumor without its own clinical manifestations. Objective: To present a case of adrenal oncocytoma and its diagnostic and therapeutic characteristics. Clinical case: 34-year-old male patient with a
Roxana Soranyer Horroutinel Scull   +3 more
doaj  

Medical Treatment of Alcoholic Liver Disease

open access: yesThe Korean Journal of Gastroenterology, 2020
Alcoholic liver disease is a major cause of liver disease that results in significant morbidity and mortality in Korea. Abstinence is the most important strategy to prevent disease progression.
Do Seon Song
doaj   +1 more source

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