Results 71 to 80 of about 131,760 (358)
Prenatal prednisone therapy (PPT)/prenatal prednisone exposure (PPE) induces long bone dysplasia, reduced peak bone mass (PBM), and increased osteoporosis susceptibility in female offspring. Maternal gut microbiota metabolite daidzein (DAI) mediates PPE‐induced osteoporosis susceptibility in female adult offspring.
Chi Ma+13 more
wiley +1 more source
ABSTRACT Neonicotinoids are widely used insecticides in agriculture, aquaculture, pet care, and urban pest control. Initially developed to selectively target the insect cholinergic system, their extensive use has raised concerns about adverse effects on nontarget vertebrates.
Kirthana Kunikullaya U+6 more
wiley +1 more source
We studied the endocrine mechanisms of urgent and long-term adaptation of children to increased physical stresses and, in particular, the role of hormones of the adrenal cortex in the regulation of the muscular activity of male athletes aged 11–15 years ...
M.V. Shaykhelislamova+4 more
doaj
Chronic adrenal insufficiency in children and adolescents
The review articles analyses modern data on etiology, pathogenesis, clinical picture in chronic adrenal insufficiency (CAI) in children and adolescents.It is indicated that, depending on the level of affection of hypothalamo-pituitary-adrenal axis ...
V. V. Smirnov, L. I. Bikbaeva
doaj
The human adrenal cortex, involved in adaptive responses to stress, body homeostasis and secondary sexual characters, emerges from a tightly regulated development of a zone-specific secretion pattern during fetal life.
E. Chamoux, M. Otis, N. Gallo-Payet
doaj +1 more source
Cell Apoptosis and Glucocorticoid‐Induced Osteonecrosis
The review identifies glucocorticoid‐induced osteocyte/osteoblast apoptosis as central to femoral head osteonecrosis (GION), mediated through STAT1‐caspase‐3, PI3K/Akt, Wnt/β‐catenin, and oxidative stress pathways. Emerging therapies targeting these pathways (e.g., HIF‐1α stabilization, AMPK activation, and exosome‐mediated miRNA delivery) show ...
Xiumei Tang+7 more
wiley +1 more source
Mechanistic crosstalk between microglia and astrocytes in major depressive disorder. Abstract Major depressive disorder (MDD) is a complex psychiatric condition increasingly linked to chronic neuroinflammation, particularly in the context of aging, stress, and systemic comorbidities.
Gaurav Singhal+2 more
wiley +1 more source
Are physiological oscillations physiological?
Abstract figure legend Mechanisms and functions of physiological oscillations. Abstract Despite widespread and striking examples of physiological oscillations, their functional role is often unclear. Even glycolysis, the paradigm example of oscillatory biochemistry, has seen questions about its oscillatory function.
Lingyun (Ivy) Xiong, Alan Garfinkel
wiley +1 more source
Introduction: Adrenal oncocytoma is a rare and incidental tumor without its own clinical manifestations. Objective: To present a case of adrenal oncocytoma and its diagnostic and therapeutic characteristics. Clinical case: 34-year-old male patient with a
Roxana Soranyer Horroutinel Scull+3 more
doaj
Medical Treatment of Alcoholic Liver Disease
Alcoholic liver disease is a major cause of liver disease that results in significant morbidity and mortality in Korea. Abstinence is the most important strategy to prevent disease progression.
Do Seon Song
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