Results 91 to 100 of about 18,480 (223)
Adrenal and Liver Transformations of Mitotane.
Mitotane, 1-(2-chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane (o,p'-DDD), a structural analog of the insecticide DDT has found use in the treatment of neoplasms derived from the adrenal cortex as well as in the treatment of Cushing's syndrome due to
Freeman, Corinne Johnson
core
SILVER BINDING NUCLEOLAR ORGANIZER REGIONS IN ADRENOCORTICAL NEOPLASIA
The possible contribution of the silver colloid technique for staining nucleolar organizer regions in the distinction between benign and malignant adrenocortical neoplasms was investigated.
OZ, B +3 more
core +1 more source
Prostate cancer, a leading cause of cancer in men globally, urgently requires improved diagnostic and treatment strategies. This study analyzed large genetic datasets and identified five key proteins (THBD, DST, IFI27L2, OSBPL10, PPP1R14A) that either increase or decrease cancer risk, while also exploring their roles in immune response and potential ...
Maoping Cai +11 more
wiley +1 more source
Somatostatin receptor expression in adrenocortical carcinomas
Background. Adrenocortical carcinoma (ACC) is a rare malignant tumor characterized by an annual incidence of 0.5—2 cases per million population. Surgery is the-first line treatment for ACC.
Galina A. Mel’nichenko +4 more
core +1 more source
ABSTRACT We undertook a computational investigation and evaluation of the impact of maternal supplementation with baru almonds (Dipteryx alata Vog.) on anxiety‐like behavior and oxidative stress in the brains of adolescent and adult rat offspring. Molecular docking studies were conducted and revealed that the phenolic compounds (PCs) from the baru ...
Diego Elias Pereira +12 more
wiley +1 more source
From chromaffin cells to Phaeochromocytoma: insight into the sympathoadrenal cell lineage
Chromaffin cells are a modified post-ganglionic sympathetic neuron, which synthesise and secrete catecholamines. The neoplastic transformation of chromaffin cells is demonstrated by the tumour phaeochromocytoma, a functional tumour that recapitulates the
Cleary, Susannah
core
Schematic representation of a large dense‐core vesicle in PC12 cells highlighting its main molecular organization. The diagram illustrates the presence of membrane transporters, proton pumps and intravesicular matrix proteins that establish the electrochemical gradients required for neurotransmitter uptake, vesicle acidification and efficient storage ...
Noemi Socas‐Pérez +2 more
wiley +1 more source
The aging paradox of Cushing's syndrome: Stress without clear senescence?
Abstract Cushing's syndrome (CS), characterized by chronic endogenous hypercortisolism and disruption of the normal circadian cortisol rhythm, represents a unique human model for investigating the interplay between stress endocrinology and biological aging.
Israel Nunes Silveira +1 more
wiley +1 more source
ABSTRACT Radiation therapy (RT) has emerged as a promising non‐surgical approach for treating canine adrenal tumours. This multi‐institutional, retrospective study describes clinical outcomes for 21 dogs having been prescribed a course of hypofractionated image‐guided intensity‐modulated RT (IMRT) entailing delivery of 25–35 Gy total in 5 fractions ...
Yen‐Hao Erik Lai +4 more
wiley +1 more source

