Results 81 to 90 of about 55,880 (237)

Hyperaldosteronism in the Pathophysiology and Management of Cardiovascular‐Kidney‐Metabolic Syndrome

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Cardiovascular‐kidney‐metabolic (CKM) syndrome is defined by the pathologic interconnections between obesity, diabetes, chronic kidney disease and cardiovascular disease. An important and underrecognized pathophysiologic factor underlying CKM syndrome is obesity‐induced aldosterone excess.
Evan Zeitler, Klara R. Klein, Ildiko Lingvay, Anthony Pick, Liana K. Billings   +4 more
wiley   +1 more source

Focal Spot, Fall/Winter 2002/2003 [PDF]

, 2003
https://digitalcommons.wustl.edu/focal_spot_archives/1092/thumbnail ...

core   +1 more source

The PI3K/Akt Pathway in Tumors of Endocrine Tissues [PDF]

, 2016
The phosphatidylinositol 3-kinase (PI3K)/Akt pathway is a key driver in carcinogenesis. Defects in this pathway in human cancer syndromes such as Cowden’s disease and Multiple Endocrine Neoplasia result in tumors of endocrine tissues, highlighting its ...
Hague, Angela, Robbins, Helen Louise
core   +2 more sources

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth, Zhou Yuxi, Yong Jiawen, Wang Lei, Ruf Sabine, Meyle Joerg   +5 more
wiley   +1 more source

A Case Report of Adrenocortical Carcinoma with Hypercortisolism and Heart Failure

پزشکی بالینی ابن سینا, 2013
Introduction: Adrenocortical carcinoma is a rare and severe malignant tumor that in 60% of cases are functional and the most common clinical manifestation is Cushing's syndrome with a progressive course.
Shiva Borzouei, Seyyed Ahmadreza Salim Bahrami, Niloofar Hemati, Hamidreza Ghadimipour   +3 more
doaj  

Association of the germline R337H mutation with breast cancer in southern Brazil [PDF]

, 2008
Background The germline TP53-R337H mutation is strongly associated with pediatric adrenocortical tumors (ACT) in southern Brazil; it has low penetrance and limited tissue specificity in most families and therefore is not associated with Li-Fraumeni ...
Srivastava Kumar, Ganti Ramapriya, Zambetti Gerard P, Ribeiro Raul C, Mastellaro Maria, Seidinger Ana, Assumpção Juliana G, Shurtleff Sheila, Pei Deqing, Zeferino Luiz, Dufloth Rozany M, Brandalise Silvia, Yunes José   +12 more
core   +2 more sources

Prolonged exposure to artificial light and carcinogenesis: A systematic review of oncostatic mechanisms associated with melatonin pathways

Photochemistry and Photobiology, EarlyView.
Exposure to artificial light at night (ALAN), particularly at blue wavelengths, disrupts circadian rhythms by suppressing melatonin, thereby increasing cancer susceptibility. This systematic review consolidates evidence linking prolonged ALAN exposure to an elevated risk of breast and prostate tumors.
Gabriel Barboza, Jêmina Oliveira, Antônio Ferreira, Renan Lopes, Marli Cupertino   +4 more
wiley   +1 more source

Pancreatic Adenocarcinoma in a Patient with IgG4-Related Autoimmune Pancreatitis: Diagnostic Challenge

Revista Brasileira de Cancerologia
Introduction: IgG4-related autoimmune pancreatitis (AIP) type 1 is a fibroinflammatory condition. An atypical case of pancreatic adenocarcinoma arising in a patient with IgG4-related AIP, which progressed despite corticosteroid therapy, raising the ...
Letícia Vieira dos Santos Ribeiro, Vítor Paulino dos Santos, Gilberto Kremer, Flávia Cristina de Novaes Gerber, Leandro Marins, Fabiana Barroso Thomaz, Leonardo de Lucca Schiavon, Janaína Luz Narciso-Schiavon   +7 more
doaj   +1 more source

Endogenous avidin biotin activity (EABA) in thyroid pathology: immunohistochemical study [PDF]

, 2009
Background Immunohistochemical methods based on the high affinity of avidin and biotin (e.g. ABC, LSAB) are characterized by high sensitivity and are widely used for detection of immunologic reaction.
Barbara Nikiel, Mykola Chekan, Michal Jarząb, Dariusz Lange   +3 more
core   +2 more sources

A Multi‐Institutional Retrospective Study of 21 Dogs Having Undergone Hypofractionated Radiotherapy for Adrenal Tumours (2017–2024)

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Radiation therapy (RT) has emerged as a promising non‐surgical approach for treating canine adrenal tumours. This multi‐institutional, retrospective study describes clinical outcomes for 21 dogs having been prescribed a course of hypofractionated image‐guided intensity‐modulated RT (IMRT) entailing delivery of 25–35 Gy total in 5 fractions ...
Yen‐Hao Erik Lai, Michael S. Kent, Michael W. Nolan, Dah‐Renn Fu, Jayme S. Looper   +4 more
wiley   +1 more source