Results 21 to 30 of about 18,480 (223)
Abstract Objectives Acute cerebral ischemia is characterized by several pathological processes evolving during time, which contribute to the final tissue damage. Secondary processes, such as prolonged inflammatory response, impaired mitochondrial function and oxidative stress, are responsible for the progression of brain injury to the peri‐infarct area,
Fioravante Capone +8 more
wiley +1 more source
Late recurrence of adrenocortical carcinoma and metastatic disease. Case report
Introduction: Adrenocortical carcinoma (ACC) is a malignancy with an annual incidence of 0.72 cases per million people. It is a rare tumor that is associated with high mortality in late stages, as well as with a 5-year survival of 13% in stage IV ...
Maria Alejandra Pérez-Ardila +4 more
doaj +1 more source
Inhibin Alpha Expression in Human Tumors: A Tissue Microarray Study on 12,212 Tumors
As a result of its expression in corresponding normal cell types, inhibin alpha (INHA) is used as an immunohistochemical marker for adrenocortical neoplasms and testicular or ovarian sex cord stromal tumors.
Sören Weidemann +24 more
doaj +1 more source
Virilizing adrenocortical oncocytoma in a toddler
Functioning adrenocortical oncocytomas are extremely rare and most reported patients are 40–60 yr of age. To our knowledge, only 6 cases of functioning adrenocortical oncocytomas have been reported in childhood.
Merna El Khansa +3 more
doaj +1 more source
Feminizing Adrenocortical Carcinoma Without Gynecomastia
Malignant feminizing adrenocortical tumors are exceedingly rare. Their main presentation is gynecomastia. In these estrogen secreting tumors (with or without other adrenocortical hormones) lack of gynecomastia is exceptional as in our case. A 44-year-old
Farida Chentli1*, +3 more
doaj +1 more source
Adrenocortical tumors (ACT) in children are very rare and are most frequently diagnosed in the context of the Li-Fraumeni syndrome, a multiple cancer syndrome linked to germline mutations of the tumor suppressor gene TP53 with loss of heterozygosity in ...
Enzo eLalli, Bonald C. Figueiredo
doaj +1 more source
Acquisition order of Ras and p53 gene alterations defines distinct adrenocortical tumor phenotypes. [PDF]
Sporadic adrenocortical carcinomas (ACC) are rare endocrine neoplasms with a dismal prognosis. By contrast, benign tumors of the adrenal cortex are common in the general population. Whether benign tumors represent a separate entity or are in fact part of
Maryline Herbet +3 more
doaj +1 more source
New developments in the pathologic diagnosis of adrenal cortical neoplasms. A review
In the past decade, our knowledge of neoplasms arising in the adrenal cortex has been expanded greatly. Histologic criteria for distinguishing benign from malignant adrenal cortical neoplasms have been developed.
Medeiros, L. J., Weiss, L. M.
core +1 more source
Adrenal Cortical Neoplasm with Uncertain Malignant Potential Arising in the Heterotopic Adrenal Cortex in the Liver of a Patient with Beckwith-Wiedemann Syndrome [PDF]
Patients with Beckwith-Wiedemann syndrome (BWS) are predisposed to developing embryonal tumors, with hepatoblastoma being the most common type. Our patient showed hemihypertrophy, macroglossia, and paternal uniparental disomy in chromosome 11 and was diagnosed with BWS.
Eun Na Kim +4 more
openaire +3 more sources
Adrenocortical carcinoma in a patient with Neurofibromatosis type 1: a case report
Background: Neurofibromatosis type 1 (NF-1) is a genetic disorder. A heterogeneous group of benign and malignant neoplasms are associated with NF-1. Adrenocortical carcinoma (ACC) is an extremely rare invasive malignancy.
Mohammad Najafi-Semnani +2 more
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