Adrenocortical neoplasia: evolving concepts in tumorigenesis with an emphasis on adrenal cortical carcinoma variants [PDF]
, 2011 Adrenocortical carcinoma (ACC) is a rare, heterogeneous malignancy with a poor prognosis. According to WHO classification 2004, ACC variants include oncocytic ACCs, myxoid ACCs and ACCs with sarcomatous areas. Herein, we provide a comprehensive review of
Ronald R. de Krijger +1 more
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Feminizing Adrenocortical Carcinoma Without Gynecomastia
Oman Medical Journal, 2017 Malignant feminizing adrenocortical tumors are exceedingly rare. Their main presentation is gynecomastia. In these estrogen secreting tumors (with or without other adrenocortical hormones) lack of gynecomastia is exceptional as in our case. A 44-year-old
Farida Chentli1*, +3 more
doaj +1 more source
Myxoid adrenal cortical adenoma and isolated adrenal myelolipoma
Наука и инновации в медицине, 2020 Objectives– to reveal the clinical, morphological and hormonal characteristics of patients operated on for isolated adrenal myelolipoma and myxoid adenomas with adrenal myelolipoma.
A. A. Lisitsyn +4 more
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Identification of numerical chromosome aberrations in archival tumours by in situ hybridization to routine paraffin sections: Evaluation of 23 phaeochromocytomas [PDF]
, 1993 We have applied non-isotopic in situ hybridization (ISH) to interphase cell nuclei of 23 phaeochromocytomas (18 primary and 5 metastatic tumours) within routine paraffin-embedded tissue sections.
Bosman, F.T.B. (Fré) +7 more
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Frontiers in Endocrinology, 2015 Adrenocortical tumors (ACT) in children are very rare and are most frequently diagnosed in the context of the Li-Fraumeni syndrome, a multiple cancer syndrome linked to germline mutations of the tumor suppressor gene TP53 with loss of heterozygosity in ...
Enzo eLalli, Bonald C. Figueiredo
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Tumors in von Hippel–Lindau Syndrome: From Head to Toe—Comprehensive State-of-the-Art Review [PDF]
, 2018 Von Hippel–Lindau syndrome (VHL) is an autosomal-dominant hereditary tumor disease that arises owing to germline mutations in the VHL gene, located on the short arm of chromosome 3.
Bhalla, Sanjeev +6 more
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Acquisition order of Ras and p53 gene alterations defines distinct adrenocortical tumor phenotypes. [PDF]
PLoS Genetics, 2012 Sporadic adrenocortical carcinomas (ACC) are rare endocrine neoplasms with a dismal prognosis. By contrast, benign tumors of the adrenal cortex are common in the general population. Whether benign tumors represent a separate entity or are in fact part of
Maryline Herbet +3 more
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Tumor classification: molecular analysis meets Aristotle [PDF]
, 2004 Background Traditionally, tumors have been classified by their morphologic appearances. Unfortunately, tumors with similar histologic features often follow different clinical courses or respond differently to chemotherapy.
Jules J Berman +29 more
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Large-scale analysis of disease pathways in the human interactome
, 2017 Discovering disease pathways, which can be defined as sets of proteins associated with a given disease, is an important problem that has the potential to provide clinically actionable insights for disease diagnosis, prognosis, and treatment ...
Agrawal, Monica +2 more
core +1 more source
Intestinal obstruction caused by neoplasms in two cows
Ciência Rural, 2016 : In cattle, abdominal tumors leading to partial or total intestinal obstruction are rare. Here, it is described the clinico-pathological findings of two cows with intestinal obstruction by neoplasms.
Antônio Carlos Lopes Câmara +3 more
doaj +1 more source