Results 161 to 170 of about 79,565 (318)

Nervonic acid, a long chain monounsaturated fatty acid, improves mitochondrial function in adrenomyeloneuropathy fibroblasts

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Nervonic acid plays a vital role in maintaining normal brain and neuronal function. Nervonic acid has gained increasing attention because of its potential neuroprotective and anti‐inflammatory properties. Nonetheless, the beneficial effects of nervonic acid are yet to be fully investigated. Adrenomyeloneuropathy (AMN), a
Chenxu Li   +2 more
wiley   +1 more source

Modeling cell differentiation in neuroblastoma: insights into development, malignancy, and treatment relapse [PDF]

open access: yesarXiv
Neuroblastoma is a paediatric extracranial solid cancer that arises from the developing sympathetic nervous system and is characterised by an abnormal distribution of cell types in tumours compared to healthy infant tissues. In this paper, we propose a new mathematical model of cell differentiation during sympathoadrenal development.
arxiv  

Advancing antihypertensive drug development

open access: yesBritish Journal of Pharmacology, EarlyView.
Hypertension affects more than a billion individuals worldwide and remains a major cause of cardiovascular morbidity and mortality. Despite advances in therapies, optimal blood pressure control remains elusive for many patients because of treatment resistance, adverse effects, and adherence challenges.
Fay Pu   +5 more
wiley   +1 more source

Transrectal ultrasonography of the adrenal glands in donkeys (Equus asinus) [PDF]

open access: yes, 2016
Little information is available for medical imaging in donkeys and no report about adrenal glands ultrasonography can be found in scientific literature. The feasibility of transrectal ultrasonography of the adrenal glands was tested on 30 healthy donkeys
Cerquetella, Matteo   +6 more
core   +1 more source

Is It Possible to Screen for Primary Aldosteronism Effectively in Primary Care?

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective Primary aldosteronism (PA) is the commonest secondary cause of hypertension but case‐detection remains a challenge. Screening is usually performed in secondary care using an aldosterone:renin ratio (ARR) measurement. Here, we describe the outcomes of screening in primary care, in Oxfordshire, UK.
Harsha Anuruddhika Dissanayake   +9 more
wiley   +1 more source

Non-Hodgkin's lymphoma presenting with primary adrenal insufficiency a disease with an underestimated frequency? [PDF]

open access: bronze, 1992
Érick Gamelin   +7 more
openalex   +1 more source

Determination of Androgen Bioactivity by an In Vitro Assay During Pubertal Transition in Healthy Boys

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective To describe the bioactivity of circulating androgens during pubertal transition as determined by an in vitro bioassay assessing androgen receptor (AR) activation, and to compare these findings with circulating concentrations of total testosterone (total T) measured by LC‐MS/MS.
Andrés Felipe Ø. Fritzbøger   +10 more
wiley   +1 more source

Periodontitis and metabolic diseases (diabetes and obesity): Tackling multimorbidity

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract Noncommunicable diseases (NCDs) are multifactorial, long‐term, chronic conditions that represent a burden to health‐care systems worldwide as they can only be controlled rather than cured; hence, they require long‐term care. With the exponential increase in NCDs, the occurrence of individuals presenting with more than one chronic disease is ...
Crystal Marruganti   +2 more
wiley   +1 more source

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