Results 271 to 280 of about 82,412 (330)

Adrenal Insufficiency [PDF]

open access: yesThe Journal of Nervous and Mental Disease, 1920
openaire   +1 more source

Mortality Patterns and Phenotypic Clusters in Trisomy 13: A Population‐Based Study From Japan

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 2, Page 329-338, February 2026.
ABSTRACT Trisomy 13, the third most common autosomal trisomy after trisomy 21 and trisomy 18, is associated with a significantly high infant mortality rate. However, large‐scale studies examining causes of death in trisomy 13 remain scarce. Therefore, we aimed to better understand the mortality patterns.
Narumi Kato   +2 more
wiley   +1 more source

Mitigating subtherapeutic cabozantinib exposure after prior mitotane therapy in adrenocortical carcinoma: Pharmacological boosting with cobicistat

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 606-611, February 2026.
Mitotane is an adrenolytic drug with cytotoxic effects, registered for the treatment of advanced adrenocortical carcinoma (ACC), a rare but aggressive tumour type with a poor prognosis despite treatment. Recently, the oral multi‐kinase inhibitor cabozantinib has shown promising results as a potential second‐line treatment option.
Annemieke M. Peters van Ton   +4 more
wiley   +1 more source

Lipopolysaccharide Upregulates Neuroinflammation, Oxidative Stress Responses, and Peroxiredoxins in Depression Models

open access: yesBrain and Behavior, Volume 16, Issue 2, February 2026.
Peroxiredoxins exhibited upregulated expression during the progression of lipopolysaccharide‐induced depression companied with neuroinflammatory and oxidative stress responses, suggesting peroxiredoxins might serve as novel strategies for the treatment of depression.
Zhifang Zhang   +9 more
wiley   +1 more source

Central Adrenal Insufficiency: Etiology and Diagnostic Approach [PDF]

open access: yesJ Clin Res Pediatr Endocrinol
Yıldız M, Yıldırım R, Baş F.
europepmc   +1 more source

Decoding Causal Associations Between Neuropsychiatric Disorders and Rotator Cuff Tendinopathy: A Two‐Sample Mendelian Randomization Study

open access: yesBrain and Behavior, Volume 16, Issue 2, February 2026.
Key findings from our study revealed that ADHD and PTSD are independent genetic risk factors for RCT in European populations after ruling out potential influence from body shape, lifestyle, socioeconomic status, and physical activity intensity Abstract Background Rotator cuff tendinopathy (RCT) is a major contributor to over 30 million surgeries which ...
Weizhe Zhang   +3 more
wiley   +1 more source

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