Results 61 to 70 of about 221,430 (290)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Primary adrenal insufficiency presenting with neuropsychiatric illness [PDF]
, 2023 Adrenal insufficiency is characterized by decreased production of glucocorticoids from adrenal cortex, either due to a primary adrenal or a secondary pituitary etiology.
Khosla, Pooja +3 more
core +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Frontiers in Endocrinology, 2023 IntroductionStatins could reduce the synthesis of steroid hormones, thereby could cause adrenal insufficiency. We investigated this risk in a large nationwide database.MethodsWe conducted a nested case-control study using a cohort of individuals ...
Sandy Maumus-Robert +7 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak +4 more
wiley +1 more source
BMC Endocrine Disorders, 2013 Background Adrenal insufficiency is a rare and potentially lethal disease if untreated. Several clinical signs and biological markers are associated with glucocorticoid failure but the importance of these factors for diagnosing adrenal insufficiency is ...
Oboni Jean-Baptiste +3 more
doaj +1 more source
Primary adrenal lymphoma as a cause of adrenal insufficiency, a report of two cases
Endocrinology, Diabetes & Metabolism Case Reports, 2020 Primary adrenal lymphoma (PAL) is a rare cause of adrenal insufficiency. More than 90% is of B-cell origin. The condition is bilateral in up to 75% of cases, with adrenal insufficiency in two of three patients.
Kaja Grønning +6 more
doaj +1 more source
Chronic adrenal insufficiency in clinical practice
, 2019 Aim. To present causes, pathogenesis, clinical presentation, diagnostics and treatment of chronic adrenal insufficiency. Materials and methods. Data from 23 scientific sources published in Russia and abroad in years 1985–2017 are presented.
Marina D. Lovanova +2 more
core +1 more source
Posterior Disconnection Syndrome in Early‐Stage Adult‐Onset Cerebral Adrenoleukodystrophy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Adult‐onset cerebral adrenoleukodystrophy is potentially treatable but often difficult to recognize before advanced cerebral involvement. Herein, we describe three men with early‐stage disease who initially presented with subtle visual complaints rather than subcortical dementia. Targeted neuropsychological testing revealed higher‐order visual
Kazuto Katsuse +13 more
wiley +1 more source
Infant With Adrenal Insufficiency and Shock
MedEdPORTAL, 2015 Introduction Adrenal insufficiency is an uncommon presentation to the emergency department (ED) but can be the cause of morbidity and mortality if not recognized and treated appropriately.
Kelly Levasseur, Katherine Cashen
doaj +1 more source