A head start: The relationship of placental factors to craniofacial and brain development
Abstract In recent years, the importance of placental function for fetal neurodevelopment has become increasingly studied. This field, known as neuroplacentology, has greatly expanded possible etiologies of neurodevelopmental disorders by exploring the influence of placental function on brain development.
Annemarie Jenna Carver+2 more
wiley +1 more source
Laparoscopic partial adrenalectomy for bilateral pheochromocytomas in a boy with von Hippel-Lindau disease [PDF]
Objectives: In adults, increasing numbers of adrenalectomies for pheochromocytomas are performed laparoscopically. We report for the first time laparoscopic bilateral subtotal adrenalectomy for pheochromocytomas in an 8-year-old boy with von Hippel ...
Bartsch, Georg+4 more
core +1 more source
ABSTRACT Objectives To determine if the assessment of CD8+ tumor‐infiltrating lymphocytes (TILs) adds prognostic information to the PD‐L1 combined positive score (CPS) in recurrent/metastatic (R/M) head and neck squamous cell carcinoma (HNSCC). Methods A retrospective case series was performed of 77 patients with R/M HNSCC between 2003 and 2019.
Catherine T. Haring+8 more
wiley +1 more source
Unusual cause of nausea and vomiting [PDF]
Adrenal insufficiency can manifest with various symptoms ranging from haemodynamic compromise to non-specific symptoms like myalgia, anorexia, and loss of weight. Aetiology can be primary adrenal disorder or secondary to suppression of HPA axis.
Nandakrishna B+2 more
doaj +1 more source
Post-Partum Pituitary Insufficiency and Livedo Reticularis Presenting a Diagnostic Challenge in a Resource Limited Setting in Tanzania: A Case Report, Clinical Discussion and Brief Review of Existing Literature. [PDF]
Pituitary disorders following pregnancy are an important yet under reported clinical entity in the developing world. Conversely, post partum panhypopituitarism has a more devastating impact on women in such settings due to high fertility rates, poor ...
A Cénac+27 more
core +3 more sources
Evidence‐based management strategies for endocrine complications after pituitary adenoma surgery
Based on the PIPOST (Population, Intervention, Professional, Outcome, Setting, and Type of Evidence) framework, evidence‐based medicine questions were developed, and a top‐down search was conducted according to the 6S model of the evidence pyramid. The literature sources were best practices, guidelines, expert consensuses, systematic reviews, meta ...
Xiaoju Miao+7 more
wiley +1 more source
Adrenal Crisis Triggered by Endogenous Thyrotoxicosis: Case Series
: Objective: Describe a group of patients who presented with thyrotoxicosis and were also found to have adrenal insufficiency. Methods: Patient cases were collected over the past year at University of North Carolina at Chapel Hill.
Mazen Al Mushref, MD+2 more
doaj
Objectives: This study aimed to assess the prevalence of adrenal insufficiency in patients with primary hypothyroidism who continued to be symptomatic despite adequate biochemical correction of hypothyroidism with synthetic levothyroxine.
Paramjit Kaur Saini+2 more
doaj +1 more source
A Bayesian Nonparametric model for textural pattern heterogeneity [PDF]
Cancer radiomics is an emerging discipline promising to elucidate lesion phenotypes and tumor heterogeneity through patterns of enhancement, texture, morphology, and shape. The prevailing technique for image texture analysis relies on the construction and synthesis of Gray-Level Co-occurrence Matrices (GLCM).
arxiv
Onset, timing, and exposure therapy of stress disorders: mechanistic insight from a mathematical model of oscillating neuroendocrine dynamics [PDF]
The hypothalamic-pituitary-adrenal (HPA) axis is a neuroendocrine system that regulates numerous physiological processes. Disruptions in the activity of the HPA axis are correlated with many stress-related diseases such as post-traumatic stress disorder (PTSD) and major depressive disorder.
arxiv +1 more source