Results 91 to 100 of about 3,006 (196)

Hyperinsulinemia and insulin resistance in prepubertal and pubertal obese girls with premature adrenarche

open access: yes, 2010
The aim of this study was to investigate the possible relationship between obesity, insulin resistance and premature adrenarche in a sample of obese prepuberetal and puberetal girls. The study was performed in obese girls.
Kokka, P.   +1 more
core   +1 more source

The relationship of the early life social-emotional environment on childhood BDNF methylation and adrenarche

open access: yes
Adrenarche is hypothesized to provide protection to a rapidly developing brain during this time (6-8 years of age), through increased production of DHEA/S, which has antioxidant properties and supports brain energetics. Brain derived neurotrophic factor (
Cruz, Tristan
core   +1 more source

Pediatric androgenetic alopecia: A distinct entity requiring a dedicated clinical framework

open access: yesJAAD Reviews
Androgenetic alopecia is traditionally conceptualized as an androgen-driven disorder of adulthood that develops in the setting of postpubertal gonadal androgen production.
Abiha Kazmi, BA   +4 more
doaj   +1 more source

Precocious Puberty and Benign Variants in Female Children: Etiology, Diagnostic Challenges, and Clinical Management

open access: yesEndocrines
Precocious puberty, defined as the onset of secondary sexual characteristics before age 8 in girls, presents a diagnostic challenge in distinguishing between normal variants and pathological conditions requiring intervention.
Roberto Paparella   +7 more
doaj   +1 more source

Prenatal paternal anxiety symptoms predict child DHEA levels and internalizing symptoms during adrenarche

open access: yesFrontiers in Behavioral Neuroscience
IntroductionThis study examined (1) whether measures of paternal anxious and depressive symptoms collected prenatally and during a follow-up assessment when the child was in middle childhood, predict child neuroendocrine outcomes, and (2) whether ...
Sherri Lee Jones   +36 more
doaj   +1 more source

Developmental changes in rabbit and dog adrenal function: a possible homologue of adrenarche in the dog

open access: yes, 1981
Histologic, hormonal, and enzymatic studies were performed in the rabbit and dog to identify maturational changes similar to human adrenarche. Development of an adrenal reticular zone was observed in both the rabbit and dog, analogous to the change in ...
R. J. Schiebinger   +4 more
core   +1 more source

Cardiometabolic outcomes in girls with premature adrenarche: a longitudinal analysis of typical vs. exaggerated presentations

open access: yes
Objectives: To evaluate cardiometabolic risk factors in girls with premature adrenarche (PA), with a specific focus on outcomes based on adrenal androgen levels (typical vs. exaggerated adrenarche).
İmal, Murat   +2 more
core   +1 more source

Hazard ratios (95% C I) of adrenarche onset among girls <9.5 years adjusted for height, weight, BMI, and waist circumference.

open access: yes, 2014
Hazard ratios (95% C I) of adrenarche onset among girls
Osul A. Chowdhury (643667)   +8 more
core   +1 more source

The Relationship Between Premature Adrenarche and Markers of Inflammation in Complete Blood Count

open access: yesJournal of Pediatric Research
Aim: Premature adrenarche (PA) has been associated with metabolic and polycystic ovary syndrome (PCOS) and, thus, with an increased risk for type 2 diabetes and cardiovascular diseases in later life.
Ferda Evin   +2 more
doaj   +1 more source

Circulating miR-1-3p precedes adrenarche and modulates adrenocortical steroidogenesis via protein kinase C signaling

open access: yes
Context Adrenarche involves maturation of the adrenal zona reticularis (ZR), but its molecular regulation is poorly understood. MicroRNAs (miRNAs) may contribute to adrenal development.
Emre Murat Altinkilic   +9 more
core   +1 more source

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