Persistent bothersome urinary frequency following stereotactic body radiation therapy for clinically localized prostate cancer: rationale for prophylactic β3-agonist in men with elevated baseline international prostate symptom scores [PDF]
Frontiers in OncologyIntroductionStereotactic body radiation therapy (SBRT) for clinically localized prostate cancer has been associated with prolonged acute obstructive and irritative lower urinary tract symptoms (LUTS).
Jennifer Zack +10 more
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The Role of BK Potassium Channels in Analgesia Produced by Alpha-2 Adrenergic Receptors [PDF]
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2016 BACKGROUND AND OBJECTIVE: Millions of people suffer from pain worldwide, and annually, great economic costs are imposed on societies for pain relief. Analgesics such as alpha-2 adrenergic receptor agonists, which have low risk of complications, can be ...
E Hooshmand +2 more
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Docking Simulations of G-Protein Coupled Receptors Uncover Crossover Binding Patterns of Diverse Ligands to Angiotensin, Alpha-Adrenergic and Opioid Receptors: Implications for Cardiovascular Disease and Addiction [PDF]
BiomoleculesRecent bioassay studies have unexpectedly supported the high (computationally predicted) binding affinities of angiotensin receptor blockers (ARBs) at α-adrenergic receptors (αARs) in isolated smooth muscle.
Harry Ridgway +3 more
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Effect of preoperative administration of systemic alpha-2 agonists on postoperative pain: a systematic review and meta-analysis [PDF]
Anesthesia and Pain Medicine, 2020 Background Alpha-2 agonists have sedative, analgesic, and opioid-sparing effects. Moreover, intraoperative or postoperative systemic administration of alpha-2 adrenergic agonists is known to reduce postoperative pain and opioid consumption.
Ji Youn Ju, Kye-Min Kim, Sangseok Lee
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Bali Journal of Anesthesiology, 2021 Pain is defined as an unpleasant sensory and emotional experience associated with actual or potential tissue damage. If the management of acute postoperative pain is not done properly, it can lead to the complication such as chronic pain.
Dewa Ayu Nyoman Isma Pratiwi +2 more
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Рациональная фармакотерапия в кардиологии, 2022 Aim. To study the structure of antihypertensive drugs prescription in pregnant women in routine practice in Kursk and Chisinau.Material and methods. The study design was observational descriptive cross-sectional.
S. V. Povetkin +6 more
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Receptor-mediated enhancement of beta adrenergic drug activity by ascorbate in vitro and in vivo. [PDF]
PLoS ONE, 2010 RATIONALE: Previous in vitro research demonstrated that ascorbate enhances potency and duration of activity of agonists binding to alpha 1 adrenergic and histamine receptors.
Patrick F Dillon +4 more
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Total intravenous anesthesia with propofol, ketamine, and lidocaine associated with dexmedetomidine or xylazine for ovariohysterectomy surgery in female dogs [PDF]
Ciência Rural, 2023 : This study compared cardiovascular and respiratory effects of dexmedetomidine and xylazine in total intravenous anesthesia with propofol, ketamine, and lidocaine.
Gustavo Antônio Boff +4 more
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The Role of Alpha-2 Agonists for Attention Deficit Hyperactivity Disorder in Children: A Review
Neurology International, 2023 Introduction: Attention Deficit Hyperactivity Disorder (ADHD) is one of the most common neurodevelopmental disorders, characterized by the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), which is marked by symptoms such as ...
Elisa E. Neuchat +8 more
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Clinically relevant concentrations of dexmedetomidine may reduce oxytocin-induced myometrium contractions in pregnant rats [PDF]
Anesthesia and Pain Medicine, 2020 Background Recently, there have been some trials to use dexmedetomidine in the obstetric field but concerns regarding the drug include changes in uterine contractions after labor.
Dong Joon Kim +5 more
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