Results 1 to 10 of about 100,872 (241)

Interaction between Nuclear Receptor and Alpha-Adrenergic Agonist Subtypes in Metabolism and Systemic Hemodynamics of Spontaneously Hypertensive Rats [PDF]

PPAR Research
Partial and full PPAR-γ agonists have shown promising effects and antihypertensive and antidiabetic agents through increased plasma adiponectin concentration.
Sheryar Afzal, Munavvar Abdul Sattar, Ibrahim Albokhadaim, Ali Attiq, Mahmoud Kandeel, Aimi Syamima Abdul Manap, Sameer M. Alhojaily   +6 more
doaj   +3 more sources

Ingestion of Fluids of the Ocular Surface Containing Eye Drops of Imidazole Derivatives—Alpha Adrenergic Receptor Agonists as Paragons [PDF]

Pharmaceuticals
Accidental poisonings by ingesting conjunctival fluid mixed with eye drops commonly involve alpha-2 adrenergic receptor agonists and tetrahydrozoline. These substances are recognized in commonly reported ingestions. Victims of all ages, otherwise in good
Ivan Šoša
doaj   +4 more sources

Effects of adrenergic .ALPHA.-agonists on the secretion of glycoproteins from the secretory cells of the rat submandibular gland.

Japanese Journal of Oral Biology, 1988
The effects of six different α-agonists: methoxamine (MET), phenylephrine (PHE), metaraminol (MTA), naphazoline (NAP), oxymetazoline (OXY), and clonidine (CLO), each administered at a dose of 8mg/kg, on the secretion of glycoprotein (GP) and fluid from the submandibular glands were studied in anesthetized rats. Salivation elicited by the drugs occurred
Chihiro Aoki, Yoshiki Iwabuchi, Taizo Masuhara   +2 more
openaire   +4 more sources

An Alpha-1A Adrenergic Receptor Agonist Prevents Acute Doxorubicin Cardiomyopathy in Male Mice. [PDF]

PLoS ONE, 2017
Alpha-1 adrenergic receptors mediate adaptive effects in the heart and cardiac myocytes, and a myocyte survival pathway involving the alpha-1A receptor subtype and ERK activation exists in vitro. However, data in vivo are limited.
Megan D Montgomery, Trevor Chan, Philip M Swigart, Bat-Erdene Myagmar, Rajesh Dash, Paul C Simpson   +5 more
doaj   +3 more sources

Costs and persistence of alpha-2 adrenergic agonists versus carbonic anhydrase inhibitors, both associated with prostaglandin analogues, for glaucoma as recorded by The United Kingdom General Practitioner Research Database

Clinical Ophthalmology, 2008
Philippe Denis1, Antoine Lafuma2, Gilles Berdeaux31Hôpital Edouard Herriot, Lyon, France; 2Cemka, Bourg-la-Reine, France; 3Alcon France, Rueil-Malmaison, FranceAbstract: The persistence and costs of carbonic anhydrase inhibitors + prostaglandin
Philippe Denis, Antoine Lafuma, Gilles Berdeaux   +2 more
doaj   +3 more sources

Alpha-2 adrenergic agonists for the prevention of cardiac complications among adults undergoing surgery [PDF]

Cochrane Database of Systematic Reviews, 2018
BACKGROUND The surgical stress response plays an important role on the pathogenesis of perioperative cardiac complications. Alpha-2 adrenergic agonists attenuate this response and may help prevent postoperative cardiac complications.
Dallas Duncan, Ashwin Sankar, W. Scott Beattie, Duminda N. Wijeysundera   +3 more
openalex   +2 more sources

Inhibition of the lipolytic action of beta-adrenergic agonists in human adipocytes by alpha-adrenergic agonists.

Journal of Lipid Research, 1981
The aim of this study was to define the role of the alpha-adrenergic receptor in the regulation of lipolysis by human adipocytes. Glycerol production by isolated human adipocytes was stimulated by the pure beta-adrenergic agonist isoproterenol in a dose ...
E E Wright, E R Simpson
doaj   +2 more sources

Alpha 2-adrenergic agonists stimulate DNA synthesis in Chinese hamster lung fibroblasts transfected with a human alpha 2-adrenergic receptor gene. [PDF]

Cell Regulation, 1990
To test the hypothesis that agents activating receptors negatively coupled to adenylyl cyclase (AC) can stimulate cell proliferation, we have expressed a human alpha 2-adrenergic receptor (alpha 2-C10) in CCL39 cells and studied the effects of alpha 2 ...
Klaus Seuwen, I Magnaldo, Brian K. Kobilka, Marc G. Caron, John W. Regan, Robert J. Lefkowitz, Jacques Pouysségur   +6 more
openalex   +2 more sources

Docking Simulations of G-Protein Coupled Receptors Uncover Crossover Binding Patterns of Diverse Ligands to Angiotensin, Alpha-Adrenergic and Opioid Receptors: Implications for Cardiovascular Disease and Addiction [PDF]

Biomolecules
Recent bioassay studies have unexpectedly supported the high (computationally predicted) binding affinities of angiotensin receptor blockers (ARBs) at α-adrenergic receptors (αARs) in isolated smooth muscle.
Harry Ridgway, Graham J. Moore, Laura Kate Gadanec, John M. Matsoukas   +3 more
doaj   +2 more sources

Protective Effects of Dexmedetomidine and Amifostine Against Radiotherapy-Induced Kidney Injury [PDF]

Life
Backgrounds: Approximately 18 million individuals were diagnosed with cancer in 2018. The rate is predicted to exceed 22 million by 2030. Radiotherapy is an essential part of cancer therapy, with well documented local and systemic side effects, including
Sule Batcik, Levent Tumkaya, Eyup Dil, Leyla Kazancioglu, Elif Gaygusuz, Zihni Acar Yazici, Zulkar Ozden, Kagan Kilinc, Tolga Mercantepe   +8 more
doaj   +2 more sources