Results 221 to 230 of about 104,693 (298)

The Beneficial and Harmful Effects of Perioperative Clonidine: Protocol for a Systematic Review With Meta-Analysis. [PDF]

Acta Anaesthesiol Scand
Birkebæk S, Kamp CB, Papadomanolakis-Pakis N, Jakobsen JC, Nikolajsen L, Uhrbrand PG.   +5 more
europepmc   +1 more source

Medetomidine, an .ALPHA.2-Adrenergic Agonist, Activates Cardiac Vagal Nerve Through Modulation of Baroreflex Control

, 2011
Shuji Shimizu, Tsuyoshi Akiyama, Toru Kawada, Yusuke Sata, Masaki Mizuno, Atsunori Kamiya, Toshiaki Shishido, Masashi Inagaki, Mikiyasu Shirai, Shunji Sano, Masaru Sugimachi   +10 more
openalex   +2 more sources

Role of pertussis toxin-sensitive G-proteins in the analgesic and anesthetic actions of alpha 2-adrenergic agonists in the rat.

Anesthesiology, 1995
Y. Hayashi, B. C. Rabin, T. Guo, M. Maze
semanticscholar   +1 more source

Posttranslational modifications of phosphodiesterase type 4 enzymes represent novel points for therapeutic targeting

The FEBS Journal, Volume 292, Issue 23, Page 6182-6194, December 2025.
Enzymes from the phosphodiesterase type 4 family (PDE4) coordinate physiological events driven by the cyclic AMP s(cAMP) signaling pathway by tightly controlling cAMP dynamics in many cell types. Key to this strict regulation is the myriad of posttranslational modifications that alter PDE4 activity, cellular location, and binding partner selection ...
Madihah Hussain, Gonzalo S. Tejeda, George S. Baillie   +2 more
wiley   +1 more source

Editorial: Case reports in psychopharmacology, volume III. [PDF]

Front Psychiatry
Stuhec M, Di Ciano P.
europepmc   +1 more source

Impact of Wild Edible Fruits of Arbutus unedo and Crataegus monogyna on Gut Motility, Contraction, Secretion, and Glucose Regulation

Neurogastroenterology &Motility, Volume 37, Issue 12, December 2025.
Impact of Wild Edible Fruits of Arbutus unedo and Crataegus monogyna on Gut Motility, Contraction, Secretion, and Glucose Regulation. ABSTRACT Background Arbutus and hawthorn fruits are commonly utilized in traditional medicine to address various gastrointestinal (GI) ailments.
Soumaya Wahabi, Kais Rtibi, Chaima Abidi, Mourad Jridi, Bernard Gressier, Hichem Sebai, Bruno Eto   +6 more
wiley   +1 more source

Enhanced pain relief with guanfacine as an adjuvant for trigeminal nerve blocks: insights from a PheWAS-guided randomized controlled study. [PDF]

Pain Med
Meier SE, Orr MB, Shotwell MS, Jerome RN, Shirey-Rice JK, Pulley JM, Edwards DA, Toye AD, Mishra P, Kesayan T.   +9 more
europepmc   +1 more source

Weight Loss‐Associated Remodeling of Adipose Tissue Immunometabolism

Obesity Reviews, Volume 26, Issue 12, December 2025.
ABSTRACT Obesity is a multifactorial condition characterized by excessive adiposity and systemic chronic low‐grade inflammation. Recent literature reflects a growing appreciation for the complex interplay between metabolism and the immune system in the pathogenesis of obesity‐related health conditions.
Paulo José Basso, Alejandro Schcolnik‐Cabrera, Mengyi Zhu, Erin Strachan, Xavier Clemente‐Casares, Sue Tsai   +5 more
wiley   +1 more source

The Genetic Blueprint of Obesity: From Pathogenesis to Novel Therapies

Obesity Reviews, Volume 26, Issue 12, December 2025.
ABSTRACT Obesity is a chronic metabolic disease characterized by disturbances in energy homeostasis, leading to excessive fat accumulation. The pathogenesis of the disease is shaped by a complex interplay of genetic, epigenetic, biological, psychological, and environmental factors.
Gašper Tonin, Stjepan Eržen, Zala Mlinarič, Dubravka Jurišić Eržen, Simon Horvat, Tanja Kunej, Jasna Klen   +6 more
wiley   +1 more source

Vibegron for overactive bladder in men with benign prostatic hyperplasia/obstruction: insights from the COURAGE trial. [PDF]

Transl Androl Urol
Saadat H, Bhojani N, Elterman D, Chughtai B.   +3 more
europepmc   +1 more source