Tamsulosin � turn a round [PDF]
Tamsulosin is a sulfamoylphen-ethylamine derivative, a potent and a selective antagonist of Alpha-1A adrenoceptor. It s approved in the treatment of LUTS in BPH disease, being a specific Alpha -1A blocker it does not interfere much with the ...
Praveen R, Int J Cur Bio Med Sci.
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Background: We evaluated ultrasonography variables associated with the improvement of nocturia after administration of alpha adrenoceptor antagonist (alpha blocker) monotherapy.
Byung Hoon Kim +5 more
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Blockade of alpha 2-adrenergic receptors in prelimbic cortex: impact on cocaine self-administration in adult spontaneously hypertensive rats following adolescent atomoxetine treatment [PDF]
RATIONALE: Research with the spontaneously hypertensive rat (SHR) model of attention deficit/hyperactivity disorder demonstrated that chronic methylphenidate treatment during adolescence increased cocaine self-administration established during adulthood ...
Baskin, Britahny M. +3 more
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Safety and efficacy of silodosin for the treatment of benign prostatic hyperplasia
Masaki Yoshida1, Junzo Kudoh2, Yukio Homma3, Kazuki Kawabe41Department of Medical Informatics, 2Department of Urology, Japan Labor Health and Welfare Organization, Kumamoto Rosai Hospital, Kumamoto, Japan; 3Department of Urology, Graduate School of ...
Yoshida M, Kudoh J, Homma Y, Kawabe K
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Functional bowel disease : a challenging frontier in gastroenterology [PDF]
The last 30 years have seen incredible advances in the science and practice of gastroenterology and hepatology. In the 1970s, the fiberoptic endoscopic revolution facilitated the visualization of the mucosa of a large segment of the gastrointestinal ...
Camilleri, Michael
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Expression and function of G-protein-coupled receptorsin the male reproductive tract [PDF]
This review focuses on the expression and function of muscarinic acetylcholine receptors (mAChRs), α1-adrenoceptors and relaxin receptors in the male reproductive tract.
ABOUD R +267 more
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The role of BK potassium channels in analgesia produced by alpha-2 adrenergic receptors [PDF]
BACKGROUND AND OBJECTIVE: Millions of people suffer from pain worldwide, and annually, great economic costs are imposed on societies for pain relief. Analgesics such as alpha-2 adrenergic receptor agonists, which have low risk of complications, can be ...
Attarzadeh-Yazd, G. +2 more
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The Role of the Sympathetic Nervous System in the Hypothermic Effect of d-Fenfluramine [PDF]
Experiments in this dissertation were conducted to characterize the effects of d-fenfluramine on body temperature and the mechanisms by which d-fenfluramine alter body temperature.
Subramanian, Srividya
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Dual alpha2C/5HT1A receptor agonist allyphenyline induces gastroprotection and inhibits fundic and colonic contractility [PDF]
Allyphenyline, a novel α2-adrenoceptor (AR) ligand, has been shown to selectively activate α2C-adrenoceptors (AR) and 5HT1A receptors, but also to behave as a neutral antagonist of α2A-ARs.
A Fletcher +81 more
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Summary: Clinical studies have shown that α1-adrenergic receptor antagonists (α-blockers) are associated with increased heart failure risk. The mechanism underlying that hazard and whether it arises from direct inhibition of cardiomyocyte α1-ARs or from ...
Jiandong Zhang, MD, PhD +14 more
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