Results 131 to 140 of about 94,283,903 (258)

Adrenergic Contraction of Human Prostate Tissues Is Maintained Under the Rab GTPase Inhibitors Nexhinib20 and CID1067700

Pharmacology Research &Perspectives, Volume 14, Issue 6, December 2026.
ABSTRACT α1‐Adrenoceptors are an important drug target in benign prostatic hyperplasia (BPH) and have been intensively studied at the expression level, but their posttranslational regulation in the prostate is widely unknown. Here we examined modulation of prostate smooth muscle contractions by inhibitors for RabGTPases, which are involved in ...
Luca Troffer, Peibin Cen, Michael Brandstetter, Yajie Xu, Patrick Keller, Leo Stadelmeier, Philipp Weinhold, Alexander Tamalunas, Christian G. Stief, Martin Hennenberg   +9 more
wiley   +1 more source

Screening the Tox21 Compound Library for Chemicals That Stimulate the Adrenergic β1 Receptor. [PDF]

Chem Res Toxicol
Adesina PA, Zhang L, Sukhawanit C, Wood S, Zhao J, Li Z, Sakamuru S, Ferguson SS, Hsieh JH, Reif DM, Huang R, Xia M.   +11 more
europepmc   +1 more source

Community Pharmacists' Perspectives and Experiences of Deprescribing in Québec, Canada: Findings From a Survey

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 6, December 2026.
ABSTRACT Background Community pharmacists in Quebec can bill for deprescribing. However, uptake remains low. We aimed to explore how community pharmacists perceive and engage in deprescribing. Methods Community pharmacists were invited to complete an online survey through a pharmacists' social media group and a newsletter.
Alexandre Campeau Calfat, Béatrice Martin, Caroline Sirois   +2 more
wiley   +1 more source

Changes in Adrenergic and Cholinergic Receptors on Human Cerebral Vessels. [PDF]

Pharmaceuticals (Basel)
Gatherer M, Brown C, Chinezu L, Manu D, Williams A, Pendower A, Ainslie J, Walker L, Attems J, Kelly L, Counts S, Carare R.   +11 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, Volume 20, Issue 11, Page 2569-2583, November 2026.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Native Mass Spectrometry Reveals Ligand-Specific Conformational Heterogeneity of the β1-Adrenergic Receptor Using Nanobody Probes. [PDF]

Anal Chem
Wang YQ, Lian GT, Chen YA, Chen R, Wu PY, Peng HH, Yen HY.   +6 more
europepmc   +1 more source

Real‐Time Neurochemical Sensing in Zebrafish: Electrochemical and Fluorescent Approaches

Analysis &Sensing, Volume 6, Issue 6, November 2026.
The use of zebrafish has emerged as a powerful approach for real‐time neurochemical measurements. This review highlights recent advances in electrochemical and fluorescent sensing strategies that enable dynamic measurements in live preparations of this complex vertebrate. These complementary approaches provide new insights into neurochemical signaling,
Piyanka Hettiarachchi, Jacob T. Theismann, Michael A. Johnson   +2 more
wiley   +1 more source

Association of <i>ADRB2</i> Gene Polymorphisms with Sporting Ability and Human Body Functions: A Literature Review. [PDF]

Genes (Basel)
Li X, Levushkin SP, Kruszewski M, Aksenov MO.   +3 more
europepmc   +1 more source

Pharmacological Modulation of Catecholaminergic Brain Injury by Dapagliflozin and Its Nanovesicular Formulation in an Isoproterenol Model

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 11, November 2026.
Bile salt–stabilized nanovesicular dapagliflozin attenuated oxidative stress, neuroinflammation, and neuronal injury while preserving stress‐response proteins and improving behavioral outcomes in an experimental model of isoproterenol‐induced catecholaminergic brain injury.
Faisal Ashraf Bhat, Syed Ehtaishamul Haque, Mohammed Aqil, Mohd Akhtar, Abul Kalam Najmi   +4 more
wiley   +1 more source

ATP Release and Purinergic Signaling Potentiate β-Adrenergic Effects on Brown Adipocytes. [PDF]

Acta Physiol (Oxf)
Tozzi M, Berggreen EB, Zhang R, Gudiksen A, Li W, Matz MB, Pilegaard H, Hansen JB, Novak I.   +8 more
europepmc   +1 more source