Results 161 to 170 of about 94,283,903 (258)

Comparison of the Utility of Amplitude-Spectral and Coherence Features of Psychotropic Drugs' Action on ECoG Signal for Pharmaco-EEG Based Drug Screening in Rats. [PDF]

Methods Protoc
Sysoev YI, Kurmazov NS, Shitc DD, Okovityi SV.   +3 more
europepmc   +1 more source

In Silico to In Cerebro—Development of the Orexin Receptor Antagonist “Photorexant” for Photomodulation In Vitro and in Mouse Brains

Angewandte Chemie International Edition, Volume 65, Issue 42, 12 October 2026.
Following a structure‐based design approach, photoswitchable derivatives of the FDA‐approved drug suvorexant were designed, docked, synthesized, and characterized pharmacologically at the orexin 1 and 2 receptors (OX1R and OX2R). Optimized “photorexant” showed up to an 11‐fold difference in IC50 between photoisomers, enabled dynamic and reversible ...
Marcus Angermann, Marie H. Deventer, Vicente Ledesma‐Martin, Nuno Martinho, Alix Flake, Silvia Mori, Angel Nuñez, Jaime Pignatelli, Rita C. Guedes, Christophe P. Stove, Michael Decker   +10 more
wiley   +1 more source

Utility of inhaled β2-agonists in reducing serum potassium levels in adult patients with hyperkalemia: A scoping review. [PDF]

PLoS One
Arzayus-Patiño L, Hinojosa-Angulo AY, Rodríguez-Angulo KA, Sánchez-Caicedo MA, Benavides-Córdoba V.   +4 more
europepmc   +1 more source

G Protein-Mediated Allosteric Modulation of Ligand Binding in Class A GPCRs: Receptor-Ligand-Transducer Ensembles in Disease and Drug Discovery. [PDF]

Pharmaceuticals (Basel)
Kurihara Y, Kurihara H.
europepmc   +1 more source

Atosiban-Associated Non-cardiogenic Pulmonary Edema in a Dichorionic Diamniotic Twin Pregnancy: A Case Report. [PDF]

Cureus
Maigre S, Meurant V.
europepmc   +1 more source

Effects of heart failure pharmacotherapy on natriuresis and diuresis: A narrative review. [PDF]

Heart Fail Rev
Jankowiak B, Ponikowski P, Biegus J.
europepmc   +1 more source

Threatened Miscarriage: Evidence-Based Status and Advances in Western Medical Treatments. [PDF]

Int J Womens Health
Wang Y, Gao Z, Yao Y, Wu Y, Jiang S, Duan Y, Zhao J, Wu X, Gao J.   +8 more
europepmc   +1 more source

Severe Burn Injury Alters Expression of Adrenergic Receptor Transcripts in a Rodent Model. [PDF]

Eur Burn J
Knappskog K, Kleinhapl J, Gladkauskas T, Fromreide S, Daltveit DS, Lowry JE, Knappskog PM, Onarheim H, Guttormsen AB, Costea DE, El Ayadi A, Song J, Wolf SE, Almeland SK.   +13 more
europepmc   +1 more source

Oxidized phosphatidylcholines inhibit airway smooth muscle β2-adrenergic receptors via protein kinase C. [PDF]

Am J Respir Cell Mol Biol
Vaghasiya J, Sikarwar A, Dalvand A, Basu S, Bagan A, Varghese N, Duaqui AA, Pandey D, Mishra S, Ravandi A, Pascoe CD, Halayko AJ, Canadian Respiratory Research Network.   +12 more
europepmc   +1 more source

Nicotinic Acetylcholine Receptor Signaling Activates Beige Adipocytes and Mediates Systemic Metabolism. [PDF]

Diabetes
Liu S, Zhu K, Zhang W, Pan T, O'Brien M, Abe I, Dale L, Piejak J, Houssein N, Zhang B, Fein M, Kajimura S, Yung R, Xu XZS, Wu J.   +14 more
europepmc   +1 more source