Results 91 to 100 of about 945,289 (264)

Safety of short-acting beta-2-adrenomimetics: clinical observations and literature review

Клинический разбор в общей медицине
Introduction. In modern clinical practice, one of the most important aspects of treatment is the safety of pharmacotherapy, which emphasizes the need for careful monitoring of the safety of drug use and patient education.
Guzel M. Bikkinina, Gulnaz U. Makarova, Yana A. Tiushevskikh, Ekaterina O. Sobianina, Iliuza I. Narynbaeva, Radik F. Gatiyatullin, Yulia N. Khamatkhanova, Olesya V. Shamsheeva   +7 more
doaj   +1 more source

Fat cell adrenergic receptors and the control of white and brown fat cell function

Journal of Lipid Research, 1993
Five adrenoceptor subtypes are involved in the adrenergic regulation of white and brown fat cell function. The effects on cAMP production and cAMP-related cellular responses are mediated through the control of adenylyl cyclase activity by the stimulatory
M Lafontan, M Berlan
doaj   +1 more source

Beta-adrenergic modulation of mucin secretion in cat trachea

, 1983
The mechanism of beta-adrenergic regulation of mucin secretion was investigated in cat trachea in vitro. beta-Adrenergic agonists increased the release of [35S]SO4-radiolabeled mucin and mucosa-submucosal adenosine 3',5'-cyclic monophosphate (cAMP ...
C. M. Liedtke, T. F. Boat, S. A. Rudolph
core   +1 more source

Cardiomyocyte Membrane‐Camouflaged Spinach Nano‐Thylakoids Enhance Myocardial Energy Metabolism and Ameliorate Heart Failure

Small, EarlyView.
Schematic illustration of the construction of MM‐NTU, its cardiac‐targeting behavior, and its light‐activated therapeutic mechanism. Thylakoids isolated from spinach chloroplasts were processed into nano‐thylakoid units (NTU) and further camouflaged with cardiomyocyte membranes to generate MM‐NTU.
Haohui Fan, Bei Song, Chengyun Liu, Peiyu Zhong, Quan Zhou, Xiaofang Zhao, Guangyu Gao, Xinyue Zhang, Xueke Guang, Tianci Yao, Ting Liu, Hao Zhang, Xinqi Diao, Weilin Lu   +13 more
wiley   +1 more source

Interleukin-13 Signaling and Its Role in Asthma

World Allergy Organization Journal, 2011
Asthma affects nearly 300 million people worldwide. The majority respond to inhaled corticosteroid treatment with or without beta-adrenergic agonists.
Efren L. Rael, MD, Richard F. Lockey, MD
doaj   +1 more source

Analysis of full and partial agonists binding to beta(2)-adrenergic receptor suggests a role of transmembrane helix V in agonist-specific conformational changes

, 2009
The 2.4 angstrom crystal structure of the beta(2)-adrenergic receptor (beta(2)AR) in complex with the high-affinity inverse agonist (-)-carazolol provides a detailed structural framework for the analysis of ligand recognition by adrenergic receptors ...
Abagyan, Ruben, Cherezov, Vadim, Katritch, Vsevolod, Roth, Christopher B., Reynolds, Kimberly A., Hanson, Michael A., Yeager, Mark   +6 more
core   +1 more source

Blubber Thickening Driven by UCP1 Inactivation: Insights from a Cetacean‐Like Transgenic Mouse Model

Integrative Zoology, EarlyView.
UCP1 inactivation of cetaceans in mice drives BAT whitening and iWAT hyperplasia, promoting fat accumulation for aquatic adaptation. Abstract Cetaceans possess thick blubber, a specialized adipose tissue essential for thermal insulation, a streamlined body form, energy storage, and buoyancy. However, the mechanisms that underpin this adaptation are not
Qian Zhang, Yuehua Wang, Hang Zhang, Guiping Xu, Shixia Xu, Guang Yang   +5 more
wiley   +1 more source

The human heart beta-adrenergic receptors. II. Coupling of beta 2-adrenergic receptors with the adenylate cyclase system.

, 1983
The beta-adrenergic stimulation of adenylate cyclase in membranes from human auricles, ventricles, and fetal heart was compared with the binding properties of beta-adrenergic receptors in human auricles.
De Smet, Jean-Marie, Pochet, Roland, Delhaye, Myriam, Christophe, Jean, Waelbroeck, Magali, Chatelain, Pierre, Taton, Gérard, Leclerc, Jean Louis, Robberecht, Patrick, Camus, Jean Claude   +9 more
core  

6‐Nitrodopamine as a Novel Mediator of Prostatic Smooth Muscle Function in Mouse and Human

Andrology, EarlyView.
ABSTRACT Background Epithelium‐derived catecholamines contribute to local regulation of genitourinary smooth muscle function, but the role of the endogenous 6‐nitrodopamine (6‐ND) in the prostate remains unknown. Objectives To determine whether 6‐ND is produced by mouse and human prostate and its role in smooth muscle regulation.
Alline Araujo Curiel, Fabio Henrique da Silva, Jéssica Mariana Dias, Luise Gabriela Santos Pereira, Douglas Rafael Martins Dias, Amanda Bueno Olivotti, André Almeida Schenka, Valéria Barbosa de Souza, Masato Tsutsui, Fabiola Zakia Monica, Edson Antunes, Gilberto De Nucci, Mariana G. de Oliveira   +12 more
wiley   +1 more source

Effects of protein concentration and beta-adrenergic agonists on ruminal bacterial communities in finishing beef heifers.

PLoS ONE
To improve animal performance and modify growth by increasing lean tissue accretion, beef cattle production has relied on use of growth promoting technologies such as beta-adrenergic agonists.
Alison P Pfau, Madison T Henniger, Kendall L Samuelson, Kristin E Hales, Clint A Löest, Mike E Hubbert, Amanda K Lindholm-Perry, Amanda M Egert-McLean, Katie M Mason, Elizabeth A Shepherd, Brynn H Voy, Phillip R Myer   +11 more
doaj   +1 more source