The sensitivities of lipolysis and fatty acid synthesis to dibutyryl-cAMP (dbcAMP), epinephrine, ractopamine and clenbuterol were quantified in vitro using porcine adipocytes.
S. Mills, C. Liu
semanticscholar +1 more source
Acute effects of beta-adrenergic agonists on porcine adipocyte metabolism in vitro.
Journal of Animal Science, 1989Backfat was obtained at slaughter from market weight hogs to study the acute effects of clenbuterol (CB), ractopamine (RAC) or epinephrine (EPI), in the presence and absence of theophylline (THEO) or adenosine deaminase (ADA), on rates of lipolysis and ...
C. Liu, J. Boyer, S. Mills
semanticscholar +1 more source
Beta-adrenergic agonists attenuate fibroblast-mediated contraction of released collagen gels.
American Journal of Physiology, 1996The effects of beta-adrenergic agonists on fibroblast-mediated collagen gel contraction were investigated. beta-Agonists isoproterenol and epinephrine significantly attenuated fibroblast-mediated gel contraction in a concentration-dependent manner ...
Tadashi Mio+5 more
semanticscholar +1 more source
Solubilisation and binding characteristics of a recombinant β2-adrenergic receptor expressed in the membrane of Escherichia coli for the multianalyte detection of β-agonists and antagonists residues in food-producing animals [PDF]
The number of substances with beta-agonistic activity, illegally introduced in meat production or in sports doping as anabolic or beta-blocking agents is increasing. Analytical methods suited for their multianalyte detection are thus necessary. In this perspective, receptor assays were developed.
Colette Duez+5 more
openaire +2 more sources
The pharmacokinetics, metabolism, and tissue residues of beta-adrenergic agonists in livestock.
Journal of Animal Science, 1998Since the early 1980s the usefulness of dietary beta-agonists to improve the efficiency of feed utilization and(or) to enhance carcass leanness in livestock species has been well documented.
David J. Smith
semanticscholar +1 more source
Evidence for a Second Desensitized State of β‐Adrenergic Receptor with Low Affinity for β‐Antagonists and Normal Reactivity towards β‐Agonists in Adipocyte Membranes Previously Exposed to β‐Antagonists [PDF]
When adipocyte membranes are successively exposed to (−)‐propranolol or (±)‐alprenolo1 at 25 or 4°C, repeatedly washed and then assayed for (−)‐[3H]dihydroalprenolol binding, the apparent number of β‐adrenergic binding sites is markedly decreased. Induction of this peculiar type of receptor desensitization does not require prolonged exposure of the ...
Daniètle Lacasa+2 more
openaire +2 more sources
Illegal use of beta-adrenergic agonists: European Community.
Journal of Animal Science, 1998The use of veterinary medicinal products within the European Community is governed by a series of directives and regulations that describe the requirements for safety, quality, and efficacy of these products.
H. Kuiper+4 more
semanticscholar +1 more source
Illegal use of beta-adrenergic agonists in the United States.
Journal of Animal Science, 1998Clenbuterol (CBL) is a member of the class of drugs called beta-agonists, which have powerful desirable and undesirable effects. Clenbuterol has the ability to increase muscle mass and residues in tissue of treated animals but can cause symptoms of acute
G. Mitchell, Gloria Dunnavan
semanticscholar +1 more source
Recent evidence has documented that increased activity of an inducible nitric oxide synthase (iNOS; type 2 NO synthase) in primary isolates of adult rat ventricular myocytes after exposure to soluble mediators in medium conditioned by lipopolysaccharide ...
D. Ungureanu-Longrois+9 more
semanticscholar +1 more source
Protein and energy requirements of animals treated with beta-adrenergic agonists: a discussion.
Journal of Animal Science, 1991Much recent work has established the efficacy of certain beta-adrenergic agonists in promoting muscle growth. These compounds also lower the deposition of body lipid.
P J Reeds, H. J. Mersmann
semanticscholar +1 more source