Results 281 to 290 of about 125,477 (319)
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The Journal of Pharmacology and Experimental Therapeutics, 1982
In vitro incubation of cells with catecholamines leads to both down regulation of beta adrenergic receptor number and desensitization of agonist-stimulated adenylate cyclase activity. These same parameters, down regulation of beta adrenergic receptor number and desensitization of adenylate cyclase activity were assessed in rat lung membranes after in ...
P J, Scarpace, I B, Abrass
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In vitro incubation of cells with catecholamines leads to both down regulation of beta adrenergic receptor number and desensitization of agonist-stimulated adenylate cyclase activity. These same parameters, down regulation of beta adrenergic receptor number and desensitization of adenylate cyclase activity were assessed in rat lung membranes after in ...
P J, Scarpace, I B, Abrass
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Effects of ?-agonists on b- and c-waves implicit for adrenergic mechanisms in cat retina
Documenta Ophthalmologica, 1987Nylidrin (buphenine) is a beta-adrenergic agonist known to dilate peripheral vessels and used therapeutically in retinal degeneration and glaucoma. We studied retinal function under beta-agonists in arterially perfused cat eyes and observed a dose-dependent, reversible increase in b-wave amplitude and a decrease in c-wave amplitude in concentrations ...
G, Niemeyer, D, Cottier, U, Gerber
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[The effect of adrenergic beta agonists on morbidity and mortality of asthma].
Presse medicale (Paris, France : 1983), 1993The frequency and severity of asthma are increasing, and since 1960 two "epidemics" of deaths have occurred. During the first one, in the 1960's, a beta-adrenergic agonist with low specificity administered in high doses was blamed and usually exonerated.
J, Bousquet, P, Godard, F B, Michel
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Response to inhaled beta-agonist in a patient receiving beta-adrenergic blockers.
Archives of internal medicine, 1984A 52-year-old man receiving long-term hemodialysis and a beta-adrenergic blocker for hypertension had symptoms of acute bronchospasm when exposed to a new hemodialyzer. Resistant to two doses of subcutaneous epinephrine (1 mL of 1:1000 dilution) and one intravenous dose of aminophylline (250 mg), the bronchospasm was rapidly relieved by metaproterenol ...
A P, Lundin +3 more
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Expert Opinion on Pharmacotherapy, 2007
Aspects of the 'beta-agonist controversy' have recently re-emerged with the publication of data implicating the long-acting beta-agonist salmeterol in increased mortality from asthma. The reasons underlying the adverse effects of beta2-agonists as a class are unclear.
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Aspects of the 'beta-agonist controversy' have recently re-emerged with the publication of data implicating the long-acting beta-agonist salmeterol in increased mortality from asthma. The reasons underlying the adverse effects of beta2-agonists as a class are unclear.
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Analytical Chemistry, 2000
A technique for coating of microplate wells with a molecularly imprinted polymer (MIP), specific for epinephrine, is presented. 3-Aminophenylboronic acid was polymerized in the presence of epinephrine using oxidation of the monomer by ammonium persulfate.
S A, Piletsky +7 more
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A technique for coating of microplate wells with a molecularly imprinted polymer (MIP), specific for epinephrine, is presented. 3-Aminophenylboronic acid was polymerized in the presence of epinephrine using oxidation of the monomer by ammonium persulfate.
S A, Piletsky +7 more
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Pfl�gers Archiv European Journal of Physiology, 1992
The major focus of this paper is the characterization and quantification of rat cardiomyocyte, cell-surface beta-adrenergic receptors labelled with the hydrophilic radioligand [3H]CGP-12177. The ventricular cardiomyocytes used in these experiments have previously been extensively studied in our laboratory and confirmed to be functionally compatible ...
M, Horackova, M, Wilkinson
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The major focus of this paper is the characterization and quantification of rat cardiomyocyte, cell-surface beta-adrenergic receptors labelled with the hydrophilic radioligand [3H]CGP-12177. The ventricular cardiomyocytes used in these experiments have previously been extensively studied in our laboratory and confirmed to be functionally compatible ...
M, Horackova, M, Wilkinson
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European Journal of Clinical Investigation, 1994
Abstract. To evaluate the effects of multiple β‐adrenergic stimulations on pulmonary surfactant phospholipids, perfused lungs from β‐adrenergic primed and non‐primed rats were challenged with the β‐agonist terbutaline in vitro. Cell‐free lung lavage, lavagable alveolar cells and lung tissue were analysed for phospholipid content and incorporation of ...
W, Bernhard, B, Müller, P, Von Wichert
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Abstract. To evaluate the effects of multiple β‐adrenergic stimulations on pulmonary surfactant phospholipids, perfused lungs from β‐adrenergic primed and non‐primed rats were challenged with the β‐agonist terbutaline in vitro. Cell‐free lung lavage, lavagable alveolar cells and lung tissue were analysed for phospholipid content and incorporation of ...
W, Bernhard, B, Müller, P, Von Wichert
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International journal of peptide and protein research, 1993
Synthesized beta 1- and beta 2-pentapeptide sequences corresponding to published adrenoceptor transmembrane activation site subtypes were investigated in vitro for selectivity in association for drug ligands of known selectivity. Both nuclear magnetic resonance spectroscopy and molecular mechanics demonstrated that structural differences among the ...
W F, Schmidt +5 more
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Synthesized beta 1- and beta 2-pentapeptide sequences corresponding to published adrenoceptor transmembrane activation site subtypes were investigated in vitro for selectivity in association for drug ligands of known selectivity. Both nuclear magnetic resonance spectroscopy and molecular mechanics demonstrated that structural differences among the ...
W F, Schmidt +5 more
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European Journal of Biochemistry, 1979
When adipocyte membranes are successively exposed to (−)‐propranolol or (±)‐alprenolo1 at 25 or 4°C, repeatedly washed and then assayed for (−)‐[3H]dihydroalprenolol binding, the apparent number of β‐adrenergic binding sites is markedly decreased. Induction of this peculiar type of receptor desensitization does not require prolonged exposure of the ...
Y, Giudicelli, D, Lacasa, B, Agli
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When adipocyte membranes are successively exposed to (−)‐propranolol or (±)‐alprenolo1 at 25 or 4°C, repeatedly washed and then assayed for (−)‐[3H]dihydroalprenolol binding, the apparent number of β‐adrenergic binding sites is markedly decreased. Induction of this peculiar type of receptor desensitization does not require prolonged exposure of the ...
Y, Giudicelli, D, Lacasa, B, Agli
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