Results 281 to 290 of about 92,710 (320)
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Inhaled beta-adrenergic receptor agonists in asthma: more harm than good?

American Journal of Respiratory and Critical Care Medicine, 1995
Asthma morbidity and mortality are on the rise in the United States and worldwide (1). These increases, in the face of advances in our understanding of the pathophysiology of asthma and increasing use of presumed safer, more effective medications, have ...
Tracy E. Barrett, B. Strom
semanticscholar   +1 more source

Tocolysis with beta-adrenergic receptor agonists.

Seminars in Perinatology, 2001
Beta-adrenergic receptor agonists have been used for tocolysis in the setting of preterm labor for more than three decades. One of these agents, ritodrine hydrochloride, is the only Federal Drug Administration (FDA) approved drug for the treatment of ...
A. Caughey, J. Parer
semanticscholar   +1 more source

Chemical Grafting of Molecularly Imprinted Homopolymers to the Surface of Microplates. Application of Artificial Adrenergic Receptor in Enzyme-Linked Assay for β-Agonists Determination

Analytical Chemistry, 2000
A technique for coating of microplate wells with a molecularly imprinted polymer (MIP), specific for epinephrine, is presented. 3-Aminophenylboronic acid was polymerized in the presence of epinephrine using oxidation of the monomer by ammonium persulfate.
Gary Barrett   +7 more
openaire   +3 more sources

Binding pockets of the beta(1)- and beta(2)-adrenergic receptors for subtype-selective agonists.

Molecular Pharmacology, 1999
We examined the subtype-selective binding site of the beta-adrenergic receptors (betaARs). The beta(1)/beta(2)-chimeric receptors showed the importance of the second and seventh transmembrane domains (TM2 and TM7) of the beta(2)AR for the binding of the ...
M. Isogaya   +6 more
semanticscholar   +1 more source

Chronic administration of beta-adrenergic agonists can mimic the stimulative effect of cold exposure on protein synthesis in rat brown adipose tissue.

Journal of Biochemistry (Tokyo), 1995
When mammals are exposed to a cold environment for a long time, the capacity of nonshivering thermogenesis by brown adipose tissue (BAT) increases in association with the stimulation of synthesis of some specific proteins and tissue hyperplasia, which ...
K. Tsukazaki   +5 more
semanticscholar   +1 more source

Characterization of cell-surface ?-adrenergic ([3H]CGP-12177) binding in adult rat ventricular myocytes: lack of regulation by ?-agonists at physiological concentrations

Pfl�gers Archiv European Journal of Physiology, 1992
The major focus of this paper is the characterization and quantification of rat cardiomyocyte, cell-surface beta-adrenergic receptors labelled with the hydrophilic radioligand [3H]CGP-12177. The ventricular cardiomyocytes used in these experiments have previously been extensively studied in our laboratory and confirmed to be functionally compatible ...
M. Horackova, M. Wilkinson
openaire   +3 more sources

β‐adrenergic priming of rats in vivo modulates the effect of β‐agonist in vitro on surfactant phospholipid metabolism of isolated lungs

European Journal of Clinical Investigation, 1994
Abstract. To evaluate the effects of multiple β‐adrenergic stimulations on pulmonary surfactant phospholipids, perfused lungs from β‐adrenergic primed and non‐primed rats were challenged with the β‐agonist terbutaline in vitro. Cell‐free lung lavage, lavagable alveolar cells and lung tissue were analysed for phospholipid content and incorporation of ...
W. Bernhard   +2 more
openaire   +3 more sources

XCI Effects of Alpha and Beta Adrenergic Agonists on Nasal Blood Flow

Annals of Otology, Rhinology and Laryngology, 1968
The conceptual framework of the alpha-beta receptor system was developed as an attempt to resolve the apparently opposite types of physiological responses to adrenergic stimuli (e.g., constriction and dilation of arterioles, contraction and relaxation of
L. Hall, R. T. Jackson
semanticscholar   +1 more source

β-Adrenergic receptor polymorphisms: relationship to the β-agonist controversy and clinical implications

Expert Opinion on Pharmacotherapy, 2007
Aspects of the 'beta-agonist controversy' have recently re-emerged with the publication of data implicating the long-acting beta-agonist salmeterol in increased mortality from asthma. The reasons underlying the adverse effects of beta2-agonists as a class are unclear.
openaire   +2 more sources

Effect of beta-adrenergic agonists on lipolysis and lipogenesis by porcine adipose tissue in vitro.

Journal of Animal Science, 1990
The effects of the beta-adrenergic agonists isoproterenol, cimaterol, ractopamine and clenbuterol on lipolysis (release of glycerol and free fatty acids) and lipogenesis (incorporation of 14C into fatty acids from [14C]glucose) was examined in porcine ...
T. A. Peterla, C. Scanes
semanticscholar   +1 more source

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