Results 151 to 160 of about 115,479 (330)

Pharmacological Characterization of a Novel Beta 3 Adrenergic Agonist, Vibegron: Evaluation of Antimuscarinic Receptor Selectivity for Combination Therapy for Overactive Bladder

Journal of Pharmacology and Experimental Therapeutics, 2017
J. D. Salvo, Hiroshi Nagabukuro, L. Wickham, Catherine Abbadie, Julie A. DeMartino, A. Fitzmaurice, Loise N. Gichuru, Alison A. Kulick, M. Donnelly, Nina Jochnowitz, Amanda L Hurley, A. Pereira, Anthony Sanfiz, G. Veronin, Katherine L. Villa, John W. Woods, Beata Zamlynny, Emanuel Zycband, G. Salituro, Tara L. Frenkl, Ann E. Weber, S. Edmondson, M. Struthers   +22 more
semanticscholar   +1 more source

Cannabigerol reverses mechanical allodynia through α2A‐adrenergic modulation of thalamocortical signaling in chemotherapy‐induced neuropathy

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade, Nathan Morris, Diana E. Sepulveda, Alonso Cortez‐Resendiz, Christopher Brandl, Jennifer E. Lausch, Mariya Starostina, Nicholas M. Graziane   +7 more
wiley   +1 more source

A role for epithelium‐derived 6‐nitrodopamine on human ureter contractility

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose To investigate the basal release of 6‐nitrodopamine (6‐ND) from human isolated ureter and the role of this novel catecholamine in the ureter contractility. Experimental Approach Ureters from 67 brain‐dead organ donors (40 males and 27 females) were used during kidney transplantation procedures.
Wilmar Azal Neto, Denis Lima Oliveira, José Britto‐Júnior, Alex Henrique Miller, Flaviano Lorenzon, Felipe Fernandes Jacintho, Valéria Barbosa de Souza, Fernanda Viviane Mariano, André Almeida Schenka, Fabiola Zakia Mónica, Adriano Fregonesi, Edson Antunes, Gilberto De Nucci   +12 more
wiley   +1 more source

Effects of beta-adrenergic antagonists in patients with chronic kidney disease: a systematic review and meta-analysis.

Journal of the American College of Cardiology, 2011
S. Badve, M. Roberts, C. Hawley, A. Cass, A. Garg, H. Krum, A. Tonkin, V. Perkovic   +7 more
semanticscholar   +1 more source

Change in mRNA Expression after Atenolol, a Beta‐adrenergic Receptor Antagonist and Association with Pharmacological Response [PDF]

, 2009
Utkarsh Kohli, Britney L. Grayson, Thomas M. Aune, Laxmi V. Ghimire, Daniel Kurnik, Christoph Stein   +5 more
openalex   +1 more source

Opioids in breast cancer: Between analgesia and modulation of tumour progression

British Journal of Pharmacology, EarlyView.
Preclinical investigations consistently demonstrate that activation of μ‐opioid receptors and δ‐opioid receptors promote proliferation, migration, angiogenesis, epithelial‐mesenchymal transition, acquisition of cancer stem cell phenotypes, and chemoresistance.
Marianna Ciwun, Anna Tankiewicz‐Kwedlo, Dariusz Pawlak   +2 more
wiley   +1 more source

Meta-analysis of the efficacy and safety of alpha2-adrenergic agonists, beta-adrenergic antagonists, and topical carbonic anhydrase inhibitors with prostaglandin analogs.

A M A Archives of Ophthalmology, 2010
A. Tanna, A. Rademaker, W. C. Stewart, R. Feldman   +3 more
semanticscholar   +1 more source

The new beta-adrenergic antagonists [PDF]

, 1984
David C. Chung, Maria J. Laschuk
openalex   +1 more source

Cardiovascular Health in Women—Across the Lifespan

Clinical Endocrinology, EarlyView.
ABSTRACT Cardiovascular disease (CVD) remains the leading cause of mortality and morbidity among women worldwide. However, CVD continues to be perceived as a predominantly male issue. CVD in women therefore remains understudied, underrecognized and undertreated.
Jaya Chandrasekhar, Jessica Yao, Simone Gong, Madhuka Wijayarathne, Monique Watts, Swati Mukherjee   +5 more
wiley   +1 more source

The Role of the Sympathetic Nervous System in the Hypothermic Effect of d-Fenfluramine [PDF]

, 2002
Experiments in this dissertation were conducted to characterize the effects of d-fenfluramine on body temperature and the mechanisms by which d-fenfluramine alter body temperature.
Subramanian, Srividya
core   +1 more source