Results 151 to 160 of about 111,593 (328)

Pharmacological Characterization of a Novel Beta 3 Adrenergic Agonist, Vibegron: Evaluation of Antimuscarinic Receptor Selectivity for Combination Therapy for Overactive Bladder

Journal of Pharmacology and Experimental Therapeutics, 2017
J. D. Salvo, Hiroshi Nagabukuro, L. Wickham, Catherine Abbadie, Julie A. DeMartino, A. Fitzmaurice, Loise N. Gichuru, Alison A. Kulick, M. Donnelly, Nina Jochnowitz, Amanda L Hurley, A. Pereira, Anthony Sanfiz, G. Veronin, Katherine L. Villa, John W. Woods, Beata Zamlynny, Emanuel Zycband, G. Salituro, Tara L. Frenkl, Ann E. Weber, S. Edmondson, M. Struthers   +22 more
semanticscholar   +1 more source

Antihypertensive therapy for pregnancy hypertension and implications for fetal and neonatal heart rate monitoring: A systematic review of randomized trials and observational studies

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Trials are mostly reassuring regarding antihypertensive effects on fetal (FHR) or neonatal heart rate (neoHR), but observational studies raise concerns about beta‐blockers, particularly the alpha/beta‐blocker labetalol. Clinicians should ascribe adverse fetal or neonatal heart rate effects to evolving underlying placental dysfunction or newborn illness,
Akalya Ganeshamoorthy, Omiete Fubara Duke, Hiten D. Mistry, Jeffrey N. Bone, Marianne Vidler, Edgardo Abalos, Katie Badawy, Asma Khalil, Peter von Dadelszen, Laura A. Magee   +9 more
wiley   +1 more source

Association of beta blockers and mortality in adults with septic shock: systematic review and meta-analysis of randomized clinical trial

Frontiers in Medicine
IntroductionSeptic shock still entails significant morbidity and mortality, with the heart being affected due to catecholamine overexpression and direct injury from sepsis.
Gustavo Adolfo Vásquez-Tirado, Claudia Vanessa Quispe-Castañeda, Edinson Dante Meregildo-Rodríguez, María Cuadra-Campos, Niler Manuel Segura-Plasencia, Yessenia Katherin Arbayza-Avalos, Hugo Nelson Alva-Guarniz, Wilson Marcial Guzmán-Aguilar, Petterson Zavaleta-Alaya   +8 more
doaj   +1 more source

Postnatal β2 adrenergic treatment improves insulin sensitivity in lambs with IUGR but not persistent defects in pancreatic islets or skeletal muscle [PDF]

, 2019
Placental insufficiency causes intrauterine growth restriction (IUGR) and disturbances in glucose homeostasis with associated β adrenergic receptor (ADRβ) desensitization.
Allen, Ronald E., Anderson, Miranda J., Antolic, Andrew T., Camacho, Leticia E., Davis, Melissa A., Goyal, Ravi, Hay, William W., Jr, Kelly, Amy C., Limesand, Sean W., Papas, Klearchos K., Steyn, Leah V., Yates, Dustin T.   +11 more
core   +1 more source

Comparison of Adrenergic Beta-receptor Antagonists in Angina Pectoris

British medical journal, 1973
U. Thadani, B. Sharma, M. Meeran, Majid Pa, W. Whitaker, S. Taylor   +5 more
semanticscholar   +1 more source

Effect of anticholinergic eye drops on intraorbital, periorbital and brain pulsation power

Acta Ophthalmologica, EarlyView.
Abstract Purpose The study aims to investigate the effect of pharmacologically reducing parasympathetic activity on ocular and cerebral pulsations, inspired by recent discoveries of a glymphatic‐like system in the eye driven by physiological pulsations.
Seyed Mohsen Ebrahimi, Niko Huotari, Ville Saarela, Marja Honkamo, Lauri Raitamaa, Vesa Korhonen, Johanna Tuunanen, Janne Kananen, Vesa Kiviniemi   +8 more
wiley   +1 more source

In vitro functional properties of the rat bladder regenerated by the bladder acellular matrix graft. [PDF]

, 1998
PurposeTo assess the response of rat urinary bladder regenerated by the homologous bladder acellular matrix graft (BAMG) to in vitro electrical and pharmacologic stimuli.Materials and methodsIn Sprague-Dawley rats, partial cystectomy (>50%) was ...
Dahiya, R, Dahms, SE, Lue, TF, Nunes, LS, Piechota, HJ, Tanagho, EA   +5 more
core   +1 more source

Studies on benzenesulfonamide derivatives with .ALPHA.- and .BETA.-adrenergic antagonistic and antihypertensive activities.

, 1982
Takashi Fujikura, K. NIIGATA, Shinichi Hashimoto, Kazuo Imai, Toichi Takenaka   +4 more
openalex   +2 more sources

Effects of beta-adrenergic antagonists in patients with chronic kidney disease: a systematic review and meta-analysis.

Journal of the American College of Cardiology, 2011
S. Badve, M. Roberts, C. Hawley, A. Cass, A. Garg, H. Krum, A. Tonkin, V. Perkovic   +7 more
semanticscholar   +1 more source

Preclinical models for evaluating psychedelics in the treatment of major depressive disorder

British Journal of Pharmacology, EarlyView.
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander, Dasha Anderson, Luke Baxter, Matthew Claydon, James Rucker, Emma S. J. Robinson   +5 more
wiley   +1 more source