Results 161 to 170 of about 111,593 (328)

Meta-analysis of the efficacy and safety of alpha2-adrenergic agonists, beta-adrenergic antagonists, and topical carbonic anhydrase inhibitors with prostaglandin analogs.

A M A Archives of Ophthalmology, 2010
A. Tanna, A. Rademaker, W. C. Stewart, R. Feldman   +3 more
semanticscholar   +1 more source

Glucocorticoids and HPA axis regulation in the stress–obesity connection: A comprehensive overview of biological, physiological and behavioural dimensions

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton, Myrte Schoenmakers, Brenda W. J. H. Penninx, Mariëtte R. Boon, Elisabeth F. C. van Rossum   +4 more
wiley   +1 more source

Effects of beta 1 selective adrenergic receptor antagonists, atenolol and betaxolol on canine ventricular arrhythmias

, 1986
Keitaro Hashimoto, Kentaro Akiyama, Harumi MITSUHASHI   +2 more
openalex   +1 more source

Role of Histone Deacetylase and Inhibitors in Cardiovascular Diseases

Cell Proliferation, EarlyView.
HDACs play an important role in the occurrence and development of cardiovascular diseases, such as myocardial hypertrophy, hypertension, and atherosclerosis. HDAC inhibitors have broad prospects for the treatment of CVD, and different HDAC subtypes can act through different mechanisms.
Li‐Ying Zhang, Yue‐Yue Wang, Ri Wen, Tie‐Ning Zhang, Ni Yang   +4 more
wiley   +1 more source

(-)-S-[3H]CGP-12177 and its use to determine the rate constants of unlabeled beta-adrenergic antagonists. [PDF]

, 1985
H. Affolter, Cornelia Hertel, K Jaeggi, M. Portenier, M. Staehelin   +4 more
openalex   +1 more source

Beta 2 Adrenergic Receptor Selective Antagonist Enhances Mechanically Stimulated Bone Anabolism in Aged Mice [PDF]

, 2022
Leah E. Worton, Sundar Srinivasan, DeWayne Threet, Brandon J. Ausk, P. Huber, Ronald Y. Kwon, Steven D. Bain, Ted S. Gross, Edith M. Gardiner   +8 more
openalex   +1 more source

Autoimmunity in MASLD: Focus on autoantibodies, anti‐apolipoprotein A1 IgG and G protein‐coupled receptors

European Journal of Clinical Investigation, EarlyView.
This review outlines the potential role of anti‐GPCR autoantibodies in MASLD/MASH, given their involvement in a wide range of diseases and their possible contribution to MASLD/MASH pathophysiology. We also focused on anti‐ApoA1 autoantibodies, sharing functional features with anti‐GPCR autoantibodies and have been shown to promote liver steatosis in ...
Sabrina Pagano, Emmanuel Somm, François R. Jornayvaz, Nicolas Vuilleumier   +3 more
wiley   +1 more source

671 Comparison of beta-adrenergic antagonists on guinea pig tracheal smooth muscle: Effects of lipid solubility, beta-1-selectivity, intrinsic sympathomimetic activity, and alpha-adrenergic antagonism

, 1991
Michael O’Connell, A HENRY, T VAUGHAN
openalex   +1 more source

Rat cardiac muscle single cell automaticity responses to alpha- and beta-adrenergic agonists and antagonists. [PDF]

, 1982
Kent Hermsmeyer, R. T. Mason, S. Griffen, Peter L. Becker   +3 more
openalex   +1 more source

Posttranslational modifications of phosphodiesterase type 4 enzymes represent novel points for therapeutic targeting

The FEBS Journal, EarlyView.
Enzymes from the phosphodiesterase type 4 family (PDE4) coordinate physiological events driven by the cyclic AMP s(cAMP) signaling pathway by tightly controlling cAMP dynamics in many cell types. Key to this strict regulation is the myriad of posttranslational modifications that alter PDE4 activity, cellular location, and binding partner selection ...
Madihah Hussain, Gonzalo S. Tejeda, George S. Baillie   +2 more
wiley   +1 more source