Results 161 to 170 of about 115,087 (327)

Cardiovascular Health in Women—Across the Lifespan

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Cardiovascular disease (CVD) remains the leading cause of mortality and morbidity among women worldwide. However, CVD continues to be perceived as a predominantly male issue. CVD in women therefore remains understudied, underrecognized and undertreated.
Jaya Chandrasekhar   +5 more
wiley   +1 more source

Glucocorticoids and HPA axis regulation in the stress–obesity connection: A comprehensive overview of biological, physiological and behavioural dimensions

open access: yesClinical Obesity, Volume 15, Issue 2, April 2025.
Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton   +4 more
wiley   +1 more source

Heart matters: How glucose‐ and lipid‐modulating drugs remodel epicardial adipose tissue accumulation, inflammatory patterns and browning

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Epicardial adipose tissue (EAT) is a metabolically active visceral fat depot located between the myocardium and the visceral pericardium, exerting direct paracrine and vasocrine effects on the heart and coronary vessels. Under physiological conditions, EAT supports myocardial energy metabolism and thermoregulation through fatty acid supply and
Elisabeth Heuboeck   +2 more
wiley   +1 more source

Predicted 3D structure for the human beta 2 adrenergic receptor and its binding site for agonists and antagonists.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2004
P. Freddolino   +7 more
semanticscholar   +1 more source

Mental stress as a trigger of cardiovascular events: A narrative review

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
Stress stimulates the prefrontal cortex that in turns activates the limbic system with subsequent activation of the autonomic nervous system. The autonomic nervous system then stimulates the heart, vessels, endocrine and immune systems with a bidirectional communication. These mechanisms increase heart rate and blood pressure, promote vasoconstriction,
Paolo Raggi
wiley   +1 more source

Dietary anthocyanidin pelargonidin activates G protein‐coupled receptor 35

open access: yesThe FEBS Journal, EarlyView.
Pelargonidin, a red‐fruit‐derived anthocyanidin, was newly identified as a dietary agonist of GPR35, a metabolite‐sensing GPCR implicated in anti‐inflammation. Through screening of dietary compounds, pelargonidin emerged as a potent GPR35 agonist, attenuating inflammation in human intestinal cells.
Fumie Nakashima   +11 more
wiley   +1 more source

5-HT2A receptor enhancement of contractile activity of the porcine urothelium and lamina propria [PDF]

open access: yes, 2016
Alexander   +29 more
core   +1 more source

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