Results 251 to 260 of about 111,593 (328)

Established and Emerging Roles of Epigenetic Regulation in Diabetic Cardiomyopathy

open access: yesDiabetes/Metabolism Research and Reviews, Volume 41, Issue 6, September 2025.
ABSTRACT An increasing number of individuals are at high risk of type 2 diabetes (T2DM) and its cardiovascular (CV) complications, which challenges healthcare systems with an increased risk of developing CV diseases. Patients with T2DM exhibit a unique cardiac phenotype termed diabetic cardiomyopathy (DCM).
Adam Russell‐Hallinan   +11 more
wiley   +1 more source

Atypical development and swift resolution of an ulcerated hemangioma: a case report. [PDF]

open access: yesJ Med Case Rep
Chakhunashvili K   +2 more
europepmc   +1 more source

The future of pharmacogenetics in the treatment of heart failure [PDF]

open access: yes, 2015
Alex S Doney   +11 more
core   +2 more sources

Recent Developments in the Optical Control of Adrenergic Signaling

open access: yesMedicinal Research Reviews, Volume 45, Issue 5, Page 1307-1322, September 2025.
ABSTRACT Adrenoceptors (ARs) play a vital role in various physiological processes and are key therapeutic targets. The advent of optical control techniques, including optogenetics and photopharmacology, offers the potential to modulate AR signaling with precise temporal and spatial resolution. In this review, we summarize the latest advancements in the
Shuang Shi   +4 more
wiley   +1 more source

β3‐Adrenoceptor Agonist Effects on the Urinary Bladder Beyond Detrusor Relaxation

open access: yesNeurourology and Urodynamics, Volume 44, Issue 7, Page 1498-1502, September 2025.
ABSTRACT Aims β3‐Adrenoceptor agonists such as mirabegron or vibegron reach pharmacokinetic steady‐state within a few days. However, maximum improvements in symptoms of the overactive bladder syndrome are reached at time points later than 4 weeks, that is, detrusor smooth muscle relaxation cannot fully explain clinical effects.
Martin C. Michel   +2 more
wiley   +1 more source

The Clinical Significance of the Subtypes of Detrusor Overactivity: A Systematic Review

open access: yesNeurourology and Urodynamics, Volume 44, Issue 7, Page 1484-1490, September 2025.
ABSTRACT Introduction Detrusor overactivity (DO) is the “occurrence of detrusor contraction(s) during filling cystometry” [7] and can be “phasic” or “terminal” [26]. The aim of this systematic review was to establish whether there is any clinical significance between the different subtypes of DO in terms of demographics, underlying pathophysiology ...
Manisha Teji   +2 more
wiley   +1 more source

Brainstem noradrenergic modulation of the kisspeptin neuron GnRH pulse generator in mice. [PDF]

open access: yesNat Commun
Vas S   +5 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy