Results 251 to 260 of about 47,199 (272)
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Evidence for a Second Desensitized State of β‐Adrenergic Receptor with Low Affinity for β‐Antagonists and Normal Reactivity towards β‐Agonists in Adipocyte Membranes Previously Exposed to β‐Antagonists

European Journal of Biochemistry, 1979
When adipocyte membranes are successively exposed to (−)‐propranolol or (±)‐alprenolo1 at 25 or 4°C, repeatedly washed and then assayed for (−)‐[3H]dihydroalprenolol binding, the apparent number of β‐adrenergic binding sites is markedly decreased. Induction of this peculiar type of receptor desensitization does not require prolonged exposure of the ...
Y, Giudicelli, D, Lacasa, B, Agli
openaire   +2 more sources

Antagonism of α- and β-adrenergic-mediated accumulations of cyclic AMP in rat cerebral cortical slices by the β-antagonist (−)alprenolol

Life Sciences, 1976
Abstract (−)Alprenolol, a compound reported to bind with a high degree of specificity and stereoselectivity to β-adrenergic receptors from rat cerebral cortex completely inhibited the accumulations of cyclic AMP elicited by maximally effective concentrations of norepinephrine and epinephrine at antagonist concentrations as low as 10 −5 M.
P, Skolnick, J W, Daly
openaire   +2 more sources

Targeted Elimination of Senescent Beta Cells Prevents Type 1 Diabetes

Cell Metabolism, 2019
Peter J Thompson   +2 more
exaly  

Natalizumab plus Interferon Beta-1a for Relapsing Multiple Sclerosis

New England Journal of Medicine, 2006
Bianca Weinstock-Guttman
exaly  

Myocardial Gene Expression in Dilated Cardiomyopathy Treated with Beta-Blocking Agents

New England Journal of Medicine, 2002
Brian D Lowes, Michael R Bristow
exaly  

p16Ink4a-induced senescence of pancreatic beta cells enhances insulin secretion

Nature Medicine, 2016
Aharon Helman   +2 more
exaly  

Beta-Blockers to Prevent Gastroesophageal Varices in Patients with Cirrhosis

New England Journal of Medicine, 2005
Jaime Bosch
exaly  

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