Results 11 to 20 of about 2,589,815 (356)

Influence of Receptor Polymorphisms on the Response to α-Adrenergic Receptor Blockers in Pheochromocytoma Patients

Biomedicines, 2022
Background: Presurgical treatment with an α-adrenergic receptor blocker is recommended to antagonize the catecholamine-induced α-adrenergic receptor mediated vasoconstriction in patients with pheochromocytoma or sympathetic paraganglioma (PPGL). There is,
Annika M. A. Berends, Mathieu S. Bolhuis, Ilja M. Nolte, Edward Buitenwerf, Thera P. Links, Henri J. L. M. Timmers, Richard A. Feelders, Elisabeth M. W. Eekhoff, Eleonora P. M. Corssmit, Peter H. Bisschop, Harm R. Haak, Ron H. N. van Schaik, Samira el Bouazzaoui, Bob Wilffert, Michiel N. Kerstens   +14 more
doaj   +1 more source

Genetically Encoded Biosensors Reveal PKA Hyperphosphorylation on the Myofilaments in Rabbit Heart Failure [PDF]

, 2016
RATIONALE: In heart failure, myofilament proteins display abnormal phosphorylation, which contributes to contractile dysfunction. The mechanisms underlying the dysregulation of protein phosphorylation on myofilaments is not clear.
Barbagallo, Federica, Bers, Donald, Bossuyt, Julie, Ferrier, William, Fu, Qin, Ginsburg, Kenneth S., Isidori, Andrea, Li, Minghui, Naro, Fabio, Patel, Hemal H., Reddy, Gopireddy R., Shi, Qian, Wang, Qingtong, West, Toni, Xiang, Yang K., Xu, Bing   +15 more
core   +1 more source

Pregnancy modifies the α2-β-adrenergic receptor functional balance in rabbit fat cells

Journal of Lipid Research, 1999
The sympathetic nervous system controls lipolysis in fat by activation of four adrenergic receptors: β1, β2, β3, and α2. During pregnancy, maternal metabolism presents anabolic and catabolic phases, characterized by modifications of fat responsiveness to
Alain Bousquet-Mélou, Carmen Muñoz, Jean Galitzky, Michel Berlan, Max Lafontan   +4 more
doaj   +1 more source

Gravin orchestrates protein kinase A and 2-adrenergic receptor signaling critical for synaptic plasticity and memory [PDF]

, 2012
A kinase-anchoring proteins (AKAPs) organize compartmentalized pools of protein kinase A (PKA) to enable localized signaling events within neurons. However, it is unclear which of the many expressed AKAPs in neurons target PKA to signaling complexes ...
Abel, T., Baillie, G.S., Canton, D.A., Day, J.P., Gelman, I.H., Grimes, Q., Guercio, L.A., Havekes, R., Huang, T., Luczak, V., Nie, T., Park, A.J., Scott, J.D.   +12 more
core   +2 more sources

Sex-Related Effects of Prenatal Stress on Region-Specific Expression of Monoamine Oxidase A and β Adrenergic Receptors in Rat Hearts

Arquivos Brasileiros de Cardiologia, 2018
Background: Prenatal stress may increase risk of developing cardiovascular disorders in adulthood. The cardiotoxic effects of catecholamines are mediated via prolonged adrenergic receptor stimulation and increased oxidative stress upon their degradation ...
Tanja Jevjdovic, Tamara Dakic, Sonja Kopanja, Iva Lakic, Predrag Vujovic, Nebojsa Jasnic, Jelena Djordjevic   +6 more
doaj   +1 more source

High-fat diet induces protein kinase A and G-protein receptor kinase phosphorylation of β2 -adrenergic receptor and impairs cardiac adrenergic reserve in animal hearts. [PDF]

, 2017
Key pointsPatients with diabetes show a blunted cardiac inotropic response to β-adrenergic stimulation despite normal cardiac contractile reserve. Acute insulin stimulation impairs β-adrenergically induced contractile function in isolated cardiomyocytes ...
Chiamvimonvat, Nipavan, Fu, Qin, Hu, Yuting, Kim, Sungjin, Li, Ning, Liu, Yongming, Wang, Qingtong, Xiang, Yang K, Xu, Bing   +8 more
core   +2 more sources

Insight into partial agonism by observing multiple equilibria for ligand-bound and Gs-mimetic nanobody-bound β1-adrenergic receptor

Nature Communications, 2017
A complex conformational energy landscape determines G-protein-coupled receptor (GPCR) signalling via intracellular binding partners (IBPs), e.g., Gs and β-arrestin.
Andras Solt, M. Bostock, B. Shrestha, Prashant Kumar, Tony Warne, C. Tate, D. Nietlispach   +6 more
semanticscholar   +1 more source

Stress-Dependent Impairment Of Passive-Avoidance Memory By Propranolol Or Naloxone [PDF]

, 2011
Previous work has shown that the effect of opioid-receptor blockade on memory modulation is critically dependent upon the intensity of stress. The current study determined the effect of adrenergic-receptor blockade on memory modulation under varied ...
Atapattu, Ranga Keshani, , \u2708, Kirby, Lynn G., , \u2789, Schneider, Allen M., Simson, Peter E., , \u2778   +3 more
core   +2 more sources

α1-Adrenergic Receptors in Neurotransmission, Synaptic Plasticity, and Cognition

Frontiers in Pharmacology, 2020
α1-adrenergic receptors are G-Protein Coupled Receptors that are involved in neurotransmission and regulate the sympathetic nervous system through binding and activating the neurotransmitter, norepinephrine, and the neurohormone, epinephrine.
Dianne M. Perez
doaj   +1 more source

Correlation of Histamine Receptors and Adrenergic Receptor in Broilers Appetite [PDF]

Archives of Razi Institute, 2022
The current study was conducted to investigate the interaction between the central adrenergic and histaminergic systems and the broiler chick’s feed intake.
M Daneshvar, M Zendehdel, B Vazir, A Asghari   +3 more
doaj   +1 more source