Results 221 to 230 of about 121,835 (341)

Reciprocal Hunger-Regulating Circuits Involving Alpha-and Beta-Adrenergic Receptors Located, Respectively, in the Ventromedial and Lateral Hypothalamus

, 1970
Sarah F. Leibowitz
openalex   +1 more source

Long‐term cost‐effectiveness of invasive urodynamic studies for overactive bladder in women

BJU International, EarlyView.
Objectives To estimate the cost‐effectiveness of using invasive urodynamic studies (UDS) in the management of women with refractory overactive bladder (OAB) symptoms using the results of the FUTURE trial. Patients and Methods The FUTURE study is the largest randomised controlled trial evaluating the clinical effectiveness of UDS with comprehensive ...
Helen Bell‐Gorrod, Praveen Thokala, Suzanne Breeman, David Cooper, Graeme MacLennan, Mohamed Abdel‐Fattah, Simon Dixon   +6 more
wiley   +1 more source

α- and β-Adrenergic Receptors as Mediators of Accumulation of Cyclic Adenosine 3',5'-Monophosphate in Specific Areas of Guinea Pig Brain

, 1971
Mark Chasin, Israel Rivkin, Frank Mamrak, S. Samaniego, Sidney M. Hess   +4 more
openalex   +1 more source

Microscopy and spectroscopy approaches to study GPCR structure and function

British Journal of Pharmacology, EarlyView.
Abstract The GPCR signalling cascade is a key pathway responsible for the signal transduction of a multitude of physical and chemical stimuli, including light, odorants, neurotransmitters and hormones. Understanding the structural and functional properties of the GPCR cascade requires direct observation of signalling processes in high spatial and ...
Tomáš Fessl, Maria Majellaro, Alexey Bondar   +2 more
wiley   +1 more source

Prognostic value of β1 adrenergic receptor autoantibodies for microvascular obstruction in patients with STEMI with Post-PCI: A prospective cohort study. [PDF]

J Transl Autoimmun
Cao N, Dang W, Xin Y, Li J, Guo S, Li Q, Chen H, Li S.   +7 more
europepmc   +1 more source

G protein‐coupled receptor‐mediated autophagy in health and disease

British Journal of Pharmacology, EarlyView.
G protein‐coupled receptors (GPCRs) constitute the largest and most diverse superfamily of mammalian transmembrane proteins. These receptors are involved in a wide range of physiological functions and are targets for more than a third of available drugs in the market. Autophagy is a cellular process involved in degrading damaged proteins and organelles
Devrim Öz‐Arslan, Zeynep Aslıhan Durer, Beki Kan   +2 more
wiley   +1 more source

β3-Adrenergic receptor antagonism improves cardiac and vascular functions but did not modulate survival in a murine resuscitated septic shock model. [PDF]

Intensive Care Med Exp
Hagimont E, Lourenco-Rodrigues MD, Chousterman BG, Yen-Potin F, Durand M, Kimmoun A.   +5 more
europepmc   +1 more source

Desensitization of beta-adrenergic receptors by beta-adrenergic agonists in a cell-free system: resensitization by guanosine 5'-(beta, gamma-imino)triphosphate and other purine nucleotides.

, 1976
Chhabirani Mukherjee, Robert J. Lefkowitz   +1 more
openalex   +1 more source

Altered desensitization and internalization patterns of rodent versus human glucose‐dependent insulinotropic polypeptide (GIP) receptors. An important drug discovery challenge

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose The gut hormone glucose‐dependent insulinotropic polypeptide (GIP) signals via the GIP receptor (GIPR), resulting in postprandial potentiation of glucose‐stimulated insulin secretion. The translation of results from rodent studies to human studies has been challenged by the unexpected effects of GIPR‐targeting compounds.
Lærke Smidt Gasbjerg, Rasmus Syberg Rasmussen, Adrian Dragan, Peter Lindquist, Josefine Ulrikke Melchiorsen, Tomasz Maciej Stepniewski, Sine Schiellerup, Esther Karen Tordrup, Sarina Gadgaard, Hüsün Sheyma Kizilkaya, Sabine Willems, Yi Zhong, Yi Wang, Shane C. Wright, Volker M. Lauschke, Bolette Hartmann, Jens Juul Holst, Jana Selent, Mette Marie Rosenkilde   +18 more
wiley   +1 more source

Nephro- and Cardiotoxic Effects of Etoricoxib: Insights into Arachidonic Acid Metabolism and Beta-Adrenergic Receptor Expression in Experimental Mice. [PDF]

Pharmaceuticals (Basel)
Jamous YF, Alghamdi BS, Jarrar Y, Hindi EA, Alam MZ, Abd El-Aziz GS, Ibrahim RF, Bakhlgi R, Algarni SM, AboTaleb HA.   +9 more
europepmc   +1 more source