Results 261 to 270 of about 2,542,862 (407)

Mechanism of adenylate cyclase activation through the beta-adrenergic receptor: catecholamine-induced displacement of bound GDP by GTP.

, 1978
Dan Cassel, Zvi Selinger
openalex   +1 more source

Ectopic beta-adrenergic receptor binding sites. possible molecular basis of aberrant catecholamine responsiveness of an adrenocortical tumor adenylate cyclase. [PDF]

, 1977
L T Williams, T B Gore, Robert J. Lefkowitz   +2 more
openalex   +1 more source

Induction of cardiac alternans in human iPS-derived cardiomyocytes through β-adrenergic receptor stimulation. [PDF]

Physiol Rep
Hinata Y, Sasaki D, Matsuura K, Shimizu T.   +3 more
europepmc   +1 more source

Subsensitivity of adenylate cyclase and decreased beta-adrenergic receptor binding after chronic exposure to (minus)-isoproterenol in vitro.

, 1975
John V. Mickey, Robert L. Tate, Robert J. Lefkowitz   +2 more
openalex   +1 more source

Safety pharmacology of acute mescaline administration in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aims Psychedelics, including mescaline, may serve as novel treatments for depression and anxiety. However, data is scarce on the safety of mescaline. Methods The present pooled analysis included two double‐blind, randomized, placebo‐controlled studies with a total of 48 participants and 96 mescaline administrations. Single oral‐dose administrations (n =
Aaron Klaiber, Mélusine Humbert‐Droz, Laura Ley, Yasmin Schmid, Matthias E. Liechti   +4 more
wiley   +1 more source

Nonselective β-Adrenergic Receptor Inhibitors Impair Hematopoietic Regeneration in Mice and Humans after Hematopoietic Cell Transplants. [PDF]

Cancer Discov
Nishino J, Hu W, Kishtagari A, Shen B, Gao X, Blackman CM, Kassim A, Marneni N, Cherukuri AV, Vittrup R, Kalkan FN, Shah R, Ahn C, Gao A, Ahmedrabie A, Collins RH, Zeidan AM, Bidikian A, Gowda L, Shaffer BC, Madanat YF, Zhao Z, Chung SS, Morrison SJ.   +23 more
europepmc   +1 more source

Preclinical models for evaluating psychedelics in the treatment of major depressive disorder

British Journal of Pharmacology, EarlyView.
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander, Dasha Anderson, Luke Baxter, Matthew Claydon, James Rucker, Emma S. J. Robinson   +5 more
wiley   +1 more source

β-adrenergic receptor-induced E-S potentiation in the dorsal and ventral hippocampus. [PDF]

Front Synaptic Neurosci
Trompoukis G, Miliou A, Papatheodoropoulos C.   +2 more
europepmc   +1 more source

Identification of alpha-adrenergic receptors in uterine smooth muscle membranes by [3H]dihydroergocryptine binding.

, 1976
L T Williams, Debra Mullikin, Robert J. Lefkowitz   +2 more
openalex   +1 more source

Polypharmacy in mice disrupts left ventricular function and structure and promotes proteome reorganisation in an age‐ and sex‐specific fashion

British Journal of Pharmacology, EarlyView.
Background and Purpose Most older people use polypharmacy (≥5 medications), particularly those with cardiovascular disease. The effects of polypharmacy on the cardiovascular system are not well described. We examined the effect of a chronic polypharmacy regimen on left ventricular (LV) function, structure and proteome in young and old mice of both ...
Trang Tran, Kevin Winardi, Scott P. Levick, Alexander Widiapradja, Gizem Gemikonakli, Susan E. Howlett, Matthew J. McKay, Mark P. Molloy, John Mach, Sarah N. Hilmer   +9 more
wiley   +1 more source