Results 31 to 40 of about 2,462,685 (262)
, 2017 This chapter will review the essential properties of adrenergic receptors in the physiology of cardiac function and in the pathology of cardiovascular disease. Following a systematic overview and a classification of adrenergic receptors, we will discuss the pathophysiological role of the sympathetic nervous system in several conditions including ...
M. Ciccarelli +4 more
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Journal of Neuroinflammation, 2019 Background Ischemic stroke provokes a neuroinflammatory response and simultaneously promotes release of epinephrine and norepinephrine by the sympathetic nervous system.
Kendra J. Lechtenberg +4 more
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β-Adrenergic agonist and antagonist regulation of autophagy in HepG2 cells, primary mouse hepatocytes, and mouse liver. [PDF]
PLoS ONE, 2014 Autophagy recently has been shown to be involved in normal hepatic function and in pathological conditions such as non-alcoholic fatty liver disease. Adrenergic signalling also is an important regulator of hepatic metabolism and function.
Benjamin L Farah +6 more
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Adrenergic Autoantibody‐Induced Postural Tachycardia Syndrome in Rabbits
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019 Background Previous studies have demonstrated that functional autoantibodies to adrenergic receptors may be involved in the pathogenesis of postural tachycardia syndrome.
Hongliang Li +10 more
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Adrenergic Receptors and Nephrone
Folia Endocrinologica Japonica, 1994 It is well known that the renal nerve plays an important role in the regulation of renal functions such as sodium and water reabsorption in the tubules as well as in the pathogenesis of essential hypertension. The renal sympathetic nerves innervate to the basement membranes of almost all nephron segments. Specific adrenergic receptors and intracellular
Satoshi Umemura, Masao Ishii
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Circadian-related heteromerization of adrenergic and dopamine D₄ receptors modulates melatonin synthesis and release in the pineal gland. [PDF]
PLoS Biology, 2012 The role of the pineal gland is to translate the rhythmic cycles of night and day encoded by the retina into hormonal signals that are transmitted to the rest of the neuronal system in the form of serotonin and melatonin synthesis and release.
Sergio González +12 more
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Frontiers in Pharmacology, 2022 Background: Cardiovascular diseases have become a major public health problem that seriously threatens human health. The cumulative effects of various cardiovascular events will eventually develop into chronic heart insufficiency and even heart failure ...
Panwei Hu +11 more
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Biased Signaling Pathways in β2-Adrenergic Receptor Characterized by 19F-NMR
Science, 2012 Choosing a Path The β2-adrenergic receptor (β2AR) is a G protein–coupled receptor that recognizes diverse ligands to trigger signaling in the cell.
Jeffrey J. Liu +4 more
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Ligands of Adrenergic Receptors: A Structural Point of View
Biomolecules, 2021 Adrenergic receptors are G protein-coupled receptors for epinephrine and norepinephrine. They are targets of many drugs for various conditions, including treatment of hypertension, hypotension, and asthma.
Yiran Wu, Liting Zeng, Suwen Zhao
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Caveolae-Independent Activation of Protein Kinase A in Rat Neonatal Myocytes
Journal of Pharmacological Sciences, 2005 Cardiomyocytes express both β1- and β2-adrenergic receptors, and these receptors play a differential role in chronotropic and inotropic effects of the heart. Caveolae are known as an important regulator of G-protein-coupled receptor signaling.
Masashi Fukutomi +4 more
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