Clinics, 2011 BACKGROUND: The molecular mechanisms involved in the genesis of the adrenocortical lesions seen in MEN1 syndrome (ACL-MEN1) remain poorly understood; loss of heterozygosity at 11q13 and somatic mutations of MEN1 are not usually found in these lesions ...
Marcia Helena Soares Costa +8 more
doaj +1 more source
The diagnosis and treatment of adrenocortical carcinoma in pregnancy: a case report
BMC Pregnancy and Childbirth, 2020 Background Pregnancy complicated with adrenocortical carcinoma (ACC) is a sporadic syndrome that is characterized by hypertension, uncontrolled hypokalemia, severe heart failure, premature delivery and other adverse effects.
Yuanli Zhang +5 more
doaj +1 more source
Immunohistochemical analysis of ghrelin expression in various types of adrenal tumors
Folia Histochemica et Cytobiologica, 2021 INTRODUCTION: Ghrelin, originally isolated from the endocrine cells of the gastric mucosa, is also expressed in many peripheral tissues, including normal adrenals and adrenocortical tumors.
Hanna Komarowska +6 more
doaj +1 more source
Molecular Genetic and Genomic Alterations in Cushing’s Syndrome and Primary Aldosteronism
Frontiers in Endocrinology, 2021 The genetic alterations that cause the development of glucocorticoid and/or mineralocorticoid producing benign adrenocortical tumors and hyperplasias have largely been elucidated over the past two decades through advances in genomics.
Crystal D. C. Kamilaris +2 more
doaj +1 more source
Differential diagnosis of adrenal masses by chemical shift and dynamic gadolinium enhanced MR imaging. [PDF]
, 2003 Chemical shift MRI is widely used for identifying adenomas, but it is not a perfect method. We determined whether combined dynamic MRI methods can lead to improved diagnostic accuracy.
Akaki, Shiro +5 more
core +1 more source
Post-Mortem Immunohistochemical Evidence of β2-Adrenergic Receptor Expression in the Adrenal Gland [PDF]
, 2019 The evidence from post-mortem biochemical studies conducted on cortisol and catecholamines suggest that analysis of the adrenal gland could provide useful information about its role in human pathophysiology and the stress response.
Alibrandi A. +10 more
core +1 more source
Giant nonfunctioning adrenal tumors: two case reports and review of the literature
Journal of Medical Case Reports, 2018 Background There are an estimated 1–2 cases per million per year of adrenocortical carcinoma in the USA. It represents a rare and aggressive malignancy; it is the second most aggressive endocrine malignant disease after anaplastic thyroid carcinoma.
George Chatzoulis +8 more
doaj +1 more source
Extra-adrenal, non-functional adrenocortical carcinoma presenting with acute abdomen: a case report
Journal of Medical Case Reports, 2020 Background Adrenocortical carcinoma is a rare malignancy, with 43% being non-functional. These may arise from adrenal rest anywhere in the embryonic pathway of the adrenal glands.
Alireza Mirsharifi +4 more
doaj +1 more source
Virilizing adrenocortical carcinoma in a child: A rare enigma
Indian Journal of Endocrinology and Metabolism, 2012 Adrenocortical carcinomas are rare tumors with an incidence of one to two cases per million population and are still more rarer in the pediatric age group.
Varuna Sipayya +4 more
doaj +1 more source
β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma
Advanced Science, EarlyView.β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto +20 more
wiley +1 more source